Abstract: The present disclosure relates to a novel oxygen-generating biodegradable surgical mesh, and to methods of making and using the novel oxygen-generating biodegradable surgical mesh. More specifically, a novel surgical mesh has been developed, wherein the surgical mesh has a flexible basic structure and comprises a plurality of pores, wherein the surgical mesh has a first face and a second opposite face, wherein the surgical mesh is made of a substantially homogeneous material comprising a biodegradable polymeric material and an oxygen-generating material.