Abstract: A system for electrical stimulation may comprise a plurality of electrodes and a processor. The processor may be configured to: define a region of interest (ROI) for electrode activation via a first subset of the plurality of electrodes; and define a second subset of electrodes, wherein each electrode within the second subset of electrodes are positioned away from the ROI such that the average distance between each electrode and the ROI is maximized. The second group of electrodes may be defined via low-discrepancy sequences or an equidistributed sequence. The plurality of electrodes may be part of a wearable garment or an implantable device. The system may be for muscle stimulation or neural simulation.

Abstract: A stimulation system may include a sensor configured to detect a physiological signal of a user, the physiological signal having a biomarker therein associated with a disorder of the user; a stimulator configured to deliver electrical stimulation to the user; and a hub device configured to receive the physiological signal from the sensor and to output a control signal to the stimulator. The control signal may cause the stimulator to deliver electrical stimulation to the user according to a stimulation protocol, the stimulation protocol treating the disorder. The hub device may be configured to output the control signal based on the biomarker of the received physiological signal. The hub device may be configured to generate another control signal for treating another disorder based on a biomarker not included in the physiological signal received from the sensor.