Abstract: A macular indentor for implantation on an eye of a patient includes a curved backbone extending from a first end to a second end and a raised pad coupled to the first end of the backbone. The raised pad extends inward from an inner face of the backbone such that, when the macular indentor is implanted on the eye, the raised pad applies pressure to the sclera of the eye which contacts the macula of the eye. The geometry of the backbone is configured to match the geometry of the eye.

Abstract: A macular indentor for implantation on an eye of a patient includes a curved backbone extending from a first end to a second end and a raised pad coupled to the first end of the backbone. The raised pad extends inward from an inner face of the backbone such that, when the macular indentor is implanted on the eye, the raised pad applies pressure to the sclera of the eye which contacts the macula of the eye. The geometry of the backbone is configured to match the geometry of the eye.

Abstract: This disclosure relates to a surgical instrument assembly useful during retinal surgery. In particular, a surgical instrument described herein may be constructed from a small gauge. A guarded blade having a reversibly exposed sharp blade tip is described. A sleeve may be used to guard the blade tip while leaving a sharp cutting tip exposed. Use of a sleeve to guard the blade while allowing the sharp tip to remain exposed may allow for safer dissection of tissues. When used for surgeries involving the eye, a blade having a polymer sleeve and a reversibly exposed tip may inhibit and/or avoid the occurrence of inadvertent retinal tissue injury. The tip can be covered with a movable cylindrical shield to protect the tip during inserting into the eye then retracted to expose the tip during the cutting procedure.

Abstract: Provided herein are pharmaceutical compositions comprising exenatide and an aqueous buffer, wherein the pharmaceutical compositions are packaged for administration via inhalation. Methods for treating diabetes mellitus are also described.

Abstract: The present invention relates to a surgical instrument assembly useful during retinal surgery. In particular, a surgical instrument described herein may be constructed from a small gauge. A guarded blade having an exposed sharp blade tip is described. A sleeve may be used to guard the blade tip while leaving a sharp cutting tip exposed. Use of a sleeve to guard the blade while allowing the sharp tip to remain exposed in the manner of the invention may allow for safer dissection of tissues. When used for surgeries involving the eye, a blade having a polymer sleeve and an exposed tip may inhibit and/or avoid the occurrence of inadvertent retinal tissue injury. For example, using a small gauge blade guarded by a polymer sleeve during retinal surgical procedures may reduce or inhibit injuries to the retinal tissue when used during retinal surgical procedures such as membrane peeling and/or dissection.

Abstract: A method for using an in-message application. The method includes: receiving a broadcast message; identifying, in the broadcast message, a reference to an external data provider; obtaining an identifier of the in-message application from the external data provider; using the identifier to identify a set of components of the in-message application, where placement of the set of components is defined by a visual structure of the in-message application, and where each of the set of components is a user interface (UI) element; associating data obtained from the external data provider with a component of the set of components; and serving the broadcast message and the data to a consumer client, where the consumer client renders the in-message application based on the visual structure.

Abstract: Various embodiments disclose an in-message application facilitating the use of third-party application programming interfaces (APIs). In particular, these in-message applications (referred to as “cards”) may be designed by a developer to access third-party API functionality. A user may then create a message referencing, e.g., a web address associated with the developer's card. The system may receive the user's message and recognize the reference. The system may then distribute an instantiation of the card to various recipients, the instantiation including elements generated using, or providing the user access to, the third party functionality.

Abstract: A macular indentor for implantation on an eye of a patient includes a curved backbone extending from a first end to a second end and a raised pad coupled to the first end of the backbone. The raised pad extends inward from an inner face of the backbone such that, when the macular indentor is implanted on the eye, the raised pad applies pressure to the sclera of the eye which contacts the macula of the eye. The geometry of the backbone is configured to match the geometry of the eye.

Abstract: A method for using an in-message application. The method includes: receiving a broadcast message; identifying, in the broadcast message, a reference to an external data provider; obtaining an identifier of the in-message application from the external data provider; using the identifier to identify a set of components of the in-message application, where placement of the set of components is defined by a visual structure of the in-message application, and where each of the set of components is a user interface (UI) element; associating data obtained from the external data provider with a component of the set of components; and serving the broadcast message and the data to a consumer client, where the consumer client renders the in-message application based on the visual structure.

Abstract: Various embodiments disclose an in-message application facilitating the use of third-party application programming interfaces (APIs). In particular, these in-message applications (referred to as “cards”) may be designed by a developer to access third-party API functionality. A user may then create a message referencing, e.g., a web address associated with the developer's card. The system may receive the user's message and recognize the reference. The system may then distribute an instantiation of the card to various recipients, the instantiation including elements generated using, or providing the user access to, the third party functionality.

Abstract: Various embodiments disclose an in-message application facilitating the use of third-party application programming interfaces (APIs). In particular, these in-message applications (referred to as “cards”) may be designed by a developer to access third-party API functionality. A user may then create a message referencing, e.g., a web address associated with the developer's card. The system may receive the user's message and recognize the reference. The system may then distribute an instantiation of the card to various recipients, the instantiation including elements generated using, or providing the user access to, the third party functionality.

Abstract: A method for using an in-message application. The method includes: receiving a broadcast message; identifying, in the broadcast message, a reference to an external data provider; obtaining an identifier of the in-message application from the external data provider; using the identifier to identify a set of components of the in-message application, where placement of the set of components is defined by a visual structure of the in-message application, and where each of the set of components is a user interface (UI) element; associating data obtained from the external data provider with a component of the set of components; and serving the broadcast message and the data to a consumer client, where the consumer client renders the in-message application based on the visual structure.

Abstract: An anti-siphon device limits the flow of a fluid from a first region of a patient's body to a second region. The device includes a housing having a spherical inner surface with a predetermined inner diameter. The housing has an inlet port for receiving fluid from the first region and an outlet port for directing fluid to the second region. The inlet port and the outlet port are disposed approximately diametrically opposite from each other. A spherical ball is disposed within the housing. The spherical ball has a ferromagnetic weight disposed off center therein. The spherical ball has an outer diameter that is less than the inner diameter of the housing so that the spherical ball is free to rotate within the housing and the fluid is free to flow between the inner surface of the housing and an outer surface of said spherical ball. The spherical ball has a circumferential recess extending through its center.

Abstract: An anti-siphon device limits the flow of a fluid from a first region of a patient's body to a second region. The device includes a housing having a spherical inner surface with a predetermined inner diameter. The housing has an inlet port for receiving fluid from the first region and an outlet port for directing fluid to the second region. The inlet port and the outlet port are disposed approximately diametrically opposite from each other. A spherical ball is disposed within the housing. The spherical ball has a ferromagnetic weight disposed off center therein. The spherical ball has an outer diameter that is less than the inner diameter of the housing so that the spherical ball is free to rotate within the housing and the fluid is free to flow between the inner surface of the housing and an outer surface of said spherical ball. The spherical ball has a circumferential recess extending through its center.