Abstract: A macular indentor for implantation on an eye of a patient includes a curved backbone extending from a first end to a second end and a raised pad coupled to the first end of the backbone. The raised pad extends inward from an inner face of the backbone such that, when the macular indentor is implanted on the eye, the raised pad applies pressure to the sclera of the eye which contacts the macula of the eye. The geometry of the backbone is configured to match the geometry of the eye.

Abstract: A macular indentor for implantation on an eye of a patient includes a curved backbone extending from a first end to a second end and a raised pad coupled to the first end of the backbone. The raised pad extends inward from an inner face of the backbone such that, when the macular indentor is implanted on the eye, the raised pad applies pressure to the sclera of the eye which contacts the macula of the eye. The geometry of the backbone is configured to match the geometry of the eye.

Abstract: This disclosure relates to a surgical instrument assembly useful during retinal surgery. In particular, a surgical instrument described herein may be constructed from a small gauge. A guarded blade having a reversibly exposed sharp blade tip is described. A sleeve may be used to guard the blade tip while leaving a sharp cutting tip exposed. Use of a sleeve to guard the blade while allowing the sharp tip to remain exposed may allow for safer dissection of tissues. When used for surgeries involving the eye, a blade having a polymer sleeve and a reversibly exposed tip may inhibit and/or avoid the occurrence of inadvertent retinal tissue injury. The tip can be covered with a movable cylindrical shield to protect the tip during inserting into the eye then retracted to expose the tip during the cutting procedure.

Abstract: A method and system for generating a set of values for respective ones of a set of parameters used in determining rotor blade profiles for a corotating coaxial rotor system. The method comprises establishing a ratio of respective desired thrusts of an upper rotor and a lower rotor of the corotating coaxial rotor system based on a desired performance of the corotating coaxial rotor system; and determining the set of values of the set of parameters from the desired thrusts ratio based on an equal rotation speed condition between the upper rotor and the lower rotor of the corotating coaxial rotor system, wherein the set of parameters includes torques of the upper rotor and the lower rotor.

Abstract: An aerial vehicle may include a first wing structure. The aerial vehicle may further include a first propeller and a second propeller disposed along the first wing structure. The aerial vehicle may further include a second wing structure disposed to intersect the first wing structure to form a cross configuration. The aerial vehicle may further include a third propeller and a fourth propeller disposed along the second wing structure. In a hovering orientation of the aerial vehicle, respective propeller rotational axes of the first and second propellers may be angled off-vertical in respective planes which may be perpendicular to a transverse axis of the first wing structure, and respective propeller rotational axes of the third and fourth propellers may be angled off-vertical in respective planes which may be perpendicular to a transverse axis of the second wing structure.

Abstract: Provided herein are pharmaceutical compositions comprising exenatide and an aqueous buffer, wherein the pharmaceutical compositions are packaged for administration via inhalation. Methods for treating diabetes mellitus are also described.

Abstract: An aerial vehicle including a first wing structure and a second wing structure which intersects the first wing structure perpendicularly at a position offset from a midpoint of a transverse axis of the first wing structure in a direction towards a first wingtip of the first wing structure. The aerial vehicle may further include a first set of at least two propellers with respective propeller rotational axes disposed side-by-side along a portion of the first wing structure extending between the midpoint of the transverse axis of the first wing structure and a second wingtip of the first wing structure. The aerial vehicle may further include a second set of at least two propellers with respective propeller rotational axes disposed side-by-side along a first portion of the second wing structure extending from a first surface of the first wing structure.

Abstract: The present invention relates to a surgical instrument assembly useful during retinal surgery. In particular, a surgical instrument described herein may be constructed from a small gauge. A guarded blade having an exposed sharp blade tip is described. A sleeve may be used to guard the blade tip while leaving a sharp cutting tip exposed. Use of a sleeve to guard the blade while allowing the sharp tip to remain exposed in the manner of the invention may allow for safer dissection of tissues. When used for surgeries involving the eye, a blade having a polymer sleeve and an exposed tip may inhibit and/or avoid the occurrence of inadvertent retinal tissue injury. For example, using a small gauge blade guarded by a polymer sleeve during retinal surgical procedures may reduce or inhibit injuries to the retinal tissue when used during retinal surgical procedures such as membrane peeling and/or dissection.

Abstract: A method for using an in-message application. The method includes: receiving a broadcast message; identifying, in the broadcast message, a reference to an external data provider; obtaining an identifier of the in-message application from the external data provider; using the identifier to identify a set of components of the in-message application, where placement of the set of components is defined by a visual structure of the in-message application, and where each of the set of components is a user interface (UI) element; associating data obtained from the external data provider with a component of the set of components; and serving the broadcast message and the data to a consumer client, where the consumer client renders the in-message application based on the visual structure.

Abstract: Various embodiments disclose an in-message application facilitating the use of third-party application programming interfaces (APIs). In particular, these in-message applications (referred to as “cards”) may be designed by a developer to access third-party API functionality. A user may then create a message referencing, e.g., a web address associated with the developer's card. The system may receive the user's message and recognize the reference. The system may then distribute an instantiation of the card to various recipients, the instantiation including elements generated using, or providing the user access to, the third party functionality.

Abstract: A macular indentor for implantation on an eye of a patient includes a curved backbone extending from a first end to a second end and a raised pad coupled to the first end of the backbone. The raised pad extends inward from an inner face of the backbone such that, when the macular indentor is implanted on the eye, the raised pad applies pressure to the sclera of the eye which contacts the macula of the eye. The geometry of the backbone is configured to match the geometry of the eye.

Abstract: A method and system for generating a set of values for respective ones of a set of parameters used in determining rotor blade profiles for a coaxial rotor system. The method includes establishing (302) a ratio of respective desired thrusts of an upper rotor (102, 602) and a lower rotor (104, 604) of the coaxial rotor system based on a desired performance of the coaxial rotor system, and determining (304) the set of values of the set of parameters from the desired thrusts ratio based on a torque balance condition between the upper rotor and the lower rotor of the coaxial rotor system.

Abstract: An aerial vehicle including a first wing structure and a second wing structure which intersects the first wing structure perpendicularly at a position offset from a midpoint of a transverse axis of the first wing structure in a direction towards a first wingtip of the first wing structure. The aerial vehicle may further include a first set of at least two propellers with respective propeller rotational axes disposed side-by-side along a portion of the first wing structure extending between the midpoint of the transverse axis of the first wing structure and a second wingtip of the first wing structure. The aerial vehicle may further include a second set of at least two propellers with respective propeller rotational axes disposed side-by-side along a first portion of the second wing structure extending from a first surface of the first wing structure.

Abstract: An aerial vehicle may include a first wing structure. The aerial vehicle may further include a first propeller and a second propeller disposed along the first wing structure. The aerial vehicle may further include a second wing structure disposed to intersect the first wing structure to form a cross configuration. The aerial vehicle may further include a third propeller and a fourth propeller disposed along the second wing structure. In a hovering orientation of the aerial vehicle, respective propeller rotational axes of the first and second propellers may be angled off-vertical in respective planes which may be perpendicular to a transverse axis of the first wing structure, and respective propeller rotational axes of the third and fourth propellers may be angled off-vertical in respective planes which may be perpendicular to a transverse axis of the second wing structure.

Abstract: A method for using an in-message application. The method includes: receiving a broadcast message; identifying, in the broadcast message, a reference to an external data provider; obtaining an identifier of the in-message application from the external data provider; using the identifier to identify a set of components of the in-message application, where placement of the set of components is defined by a visual structure of the in-message application, and where each of the set of components is a user interface (UI) element; associating data obtained from the external data provider with a component of the set of components; and serving the broadcast message and the data to a consumer client, where the consumer client renders the in-message application based on the visual structure.

Abstract: Various embodiments disclose an in-message application facilitating the use of third-party application programming interfaces (APIs). In particular, these in-message applications (referred to as “cards”) may be designed by a developer to access third-party API functionality. A user may then create a message referencing, e.g., a web address associated with the developer's card. The system may receive the user's message and recognize the reference. The system may then distribute an instantiation of the card to various recipients, the instantiation including elements generated using, or providing the user access to, the third party functionality.

Abstract: A method and system for generating a set of values for respective ones of a set of parameters used in determining rotor blade profiles for a coaxial rotor system. The method includes establishing (302) a ratio of respective desired thrusts of an upper rotor (102, 602) and a lower rotor (104, 604) of the coaxial rotor system based on a desired performance of the coaxial rotor system, and determining (304) the set of values of the set of parameters from the desired thrusts ratio based on a torque balance condition between the upper rotor and the lower rotor of the coaxial rotor system.

Abstract: An unmanned aerial vehicle (UAV) capable of vertical and horizontal flight modes, a method of assembling a UAV, and a kit of parts for assembling a UAV. The UAV comprises an elongated wing structure having an elongated axis along the longest dimension of the elongated wing structure, the elongated wing structure having a middle location at a substantially halfway point; a connecting structure extending substantially perpendicularly from the elongated wing structure, the connecting structure being offset from the middle location of the elongated wing structure at a first position along the elongated axis; and at least three sets of propellers, wherein at least two sets of propellers are mounted on the connecting structure, and wherein at least one set of propellers is mounted at a second position offset from the middle location in an opposite direction away from the connecting structure.

Abstract: Various embodiments disclose an in-message application facilitating the use of third-party application programming interfaces (APIs). In particular, these in-message applications (referred to as “cards”) may be designed by a developer to access third-party API functionality. A user may then create a message referencing, e.g., a web address associated with the developer's card. The system may receive the user's message and recognize the reference. The system may then distribute an instantiation of the card to various recipients, the instantiation including elements generated using, or providing the user access to, the third party functionality.

Abstract: A method for using an in-message application. The method includes: receiving a broadcast message; identifying, in the broadcast message, a reference to an external data provider; obtaining an identifier of the in-message application from the external data provider; using the identifier to identify a set of components of the in-message application, where placement of the set of components is defined by a visual structure of the in-message application, and where each of the set of components is a user interface (UI) element; associating data obtained from the external data provider with a component of the set of components; and serving the broadcast message and the data to a consumer client, where the consumer client renders the in-message application based on the visual structure.