Patents by Inventor Ian D. Fleming

Ian D. Fleming has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pure salts of clavulanic acid, e.g. lithium clavulanate
    Patent number: 4490294
    Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]-heptane -2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.
    Type: Grant
    Filed: March 20, 1978
    Date of Patent: December 25, 1984
    Assignee: Beecham Group p.l.c.
    Inventors: Ian D. Fleming, David Noble, Hazel M. Noble, Wilfred F. Wall
  • Pure sodium salt of clavulanic acid
    Patent number: 4490295
    Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]heptane- 2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.
    Type: Grant
    Filed: May 7, 1980
    Date of Patent: December 25, 1984
    Assignee: Beecham Group p.1.c.
    Inventors: Ian D. Fleming, David Noble, Hazel M. Noble (formerly Gillett), Wilfred F. Wall
  • Pure potassium salt of clavulanic acid
    Patent number: 4367175
    Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]-heptane -2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.
    Type: Grant
    Filed: May 7, 1980
    Date of Patent: January 4, 1983
    Assignee: Glaxo Laboratories Limited
    Inventors: Ian D. Fleming, David Noble, Hazel M. Noble formerly Gillett, Wilfred F. Wall
  • O-Transcarbamoylase
    Patent number: 4164447
    Abstract: A novel O-transcarbamoylase enzyme and its use in preparing a variety of 3-carbamoyloxymethyl cephalosporins from 3-hydroxymethyl cephalosporins and carbamoyl compounds are described.
    Type: Grant
    Filed: November 22, 1977
    Date of Patent: August 14, 1979
    Assignee: Glaxo Laboratories Limited
    Inventors: Ian D. Fleming, Michael K. Turner, Stephen J. Brewer
  • Process for the purification of clavulanic acid
    Patent number: 4144242
    Abstract: The invention provides the compound (2R,5R,Z)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo-[3,2,0]-heptane -2-carboxylic acid and its salts in purified form and pharmaceutical compositions containing them and a process for the purification of such compounds by conversion in aqueous media to the lithium salt of the above acid and precipitation thereof.
    Type: Grant
    Filed: December 16, 1976
    Date of Patent: March 13, 1979
    Assignee: Glaxo Laboratories Limited
    Inventors: Ian D. Fleming, David Noble, Hazel M. Noble (formerly Gillett), Wilfred F. Wall
  • Method for producing cephalosporins
    Patent number: 4075061
    Abstract: A novel O-transcarbamoylase enzyme and its use in preparing a variety of 3-carbamoyloxymethyl cephalosporins from 3-hydroxymethyl cephalosporins and carbamoyl compounds are described.
    Type: Grant
    Filed: February 15, 1977
    Date of Patent: February 21, 1978
    Assignee: Glaxo Laboratories Limited
    Inventors: Ian D. Fleming, Michael K. Turner, Stephen J. Brewer