Patents by Inventor Ian GLASSFORD

Ian GLASSFORD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cytotoxic agents and conjugates thereof
    Patent number: 10654873
    Abstract: Provided herein are novel maytansinoid compounds of general formula I. Also provided herein are conjugates comprising the compounds linked to a binding protein via a linker, and conjugating reagents comprising the compounds attached via a linker to at least one functional group capable of reacting with a binding protein. Also provided herein are pharmaceutical compositions comprising the compounds and conjugates, therapeutic methods and uses involving the compounds and conjugates, for example in cancer therapy, and novel synthetic processes.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: May 19, 2020
    Assignee: POLYTHERICS LIMITED
    Inventors: Nareshkumar Jain, Sanjeevani Ghone, Sean Smith, Ian Glassford, Sylvia J. Degrado, Fu-an Kang, Senzhi Zhao
  • Novel Cytotoxic Agents And Conjugates Thereof
    Publication number: 20190202839
    Abstract: Provided herein are novel maytansinoid compounds of general formula I. Also provided herein are conjugates comprising the compounds linked to a binding protein via a linker, and conjugating reagents comprising the compounds attached via a linker to at least one functional group capable of reacting with a binding protein. Also provided herein are pharmaceutical compositions comprising the compounds and conjugates, therapeutic methods and uses involving the compounds and conjugates, for example in cancer therapy, and novel synthetic processes.
    Type: Application
    Filed: September 15, 2017
    Publication date: July 4, 2019
    Inventors: Nareshkumar JAIN, Sanjeevani GHONE, Sean SMITH, Ian GLASSFORD, Sylvia J. DEGRADO, Fu-an KANG, Senzhi ZHAO