Patents by Inventor Ian Goodsell

Ian Goodsell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid sequences encoding protein disulfide isomerase
    Patent number: 7238513
    Abstract: Protein disulfide isomerase is a major component of Conus venom ducts. The invention relates to a protein disulfide isomerase (PDI) from Conus snails, a nucleic acid sequence encoding the Conus protein disulfide isomerase, and to methods for folding disulfide-rich peptides using a protein disulfide isomerase. Oxidative folding of conotoxin precursors, catalyzed by a PDI, was more efficient and decreased the number and concentration of transiently accumulated folding species. The PDI-assisted oxidative folding of conotoxins was also influenced by the propeptide relative to the mature peptide.
    Type: Grant
    Filed: August 31, 2005
    Date of Patent: July 3, 2007
    Assignees: University of Utah Research Foundation, Cognetix, Inc.
    Inventors: Grzegorz Bulaj, Baldomero M. Olivera, Olga Buczek, James E. Garrett, Ian Goodsell
  • Conus protein disulfide isomerase
    Publication number: 20060199245
    Abstract: Protein disulfide isomerase is a major component of Conus venom ducts. The invention relates to a protein disulfide isomerase (PDI) from Conus snails, a nucleic acid sequence encoding the Conus protein disulfide isomerase, and to methods for folding disulfide-rich peptides using a protein disulfide isomerase. Oxidative folding of conotoxin precursors, catalyzed by a PDI, was more efficient and decreased the number and concentration of transiently accumulated folding species. The PDI-assisted oxidative folding of conotoxins was also influenced by the propeptide relative to the mature peptide.
    Type: Application
    Filed: August 31, 2005
    Publication date: September 7, 2006
    Inventors: Grzegorz Bulaj, Baldomero Olivera, Olga Buczek, James Garrett, Ian Goodsell
  • Conus protein disulfide isomerase
    Publication number: 20040203132
    Abstract: Protein disulfide isomerase is a major component of Conus venom ducts. The invention relates to a protein disulfide isomerase (PDI) from Conus snails, a nucleic acid sequence encoding the Conus protein disulfide isomerase, and to methods for folding disulfide-rich peptides using a protein disulfide isomerase. Oxidative folding of conotoxin precursors, catalyzed by a PDI, was more efficient and decreased the number and concentration of transiently accumulated folding species. The PDI-assisted oxidative folding of conotoxins was also influenced by the propeptide relative to the mature peptide.
    Type: Application
    Filed: February 27, 2004
    Publication date: October 14, 2004
    Applicant: Cognetix, Inc.
    Inventors: Grzegorz Bulaj, Baldomero M. Olivera, Olga Buczek, James E. Garrett, Ian Goodsell