Patents by Inventor Ian Gould
Ian Gould has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11332419Abstract: Synthesizing an alkane includes heating a mixture including an alkene and water at or above the water vapor saturation pressure in the presence of a catalyst and one or both of hydrogen and a reductant, thereby hydrogenating the alkene to yield an alkane and water, and separating the alkane from the water to yield the alkane. The reductant includes a first metal and the catalyst includes a second metal.Type: GrantFiled: September 30, 2020Date of Patent: May 17, 2022Assignee: Arizona Board of Regents on behalf of Arizona State UniversityInventors: Kirtland Robinson, Ian Gould, Christiana Bockisch, Everett Shock, Hilairy Hartnett, Lynda B. Williams
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Publication number: 20210230088Abstract: Oxidizing a first aromatic compound in the presence of a metal salt to yield a second aromatic compound includes combining the first aromatic compound, the metal salt, and water to yield an aqueous mixture, and heating the aqueous mixture at a temperature exceeding 200° C. to yield a reaction product that includes the second aromatic compound.Type: ApplicationFiled: January 25, 2021Publication date: July 29, 2021Inventors: Grant Loescher, Everett Shock, Ian Gould, Hilairy Hartnett, Lynda B. Williams
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Publication number: 20210107847Abstract: Synthesizing an alkane includes heating a mixture including an alkene and water at or above the water vapor saturation pressure in the presence of a catalyst and one or both of hydrogen and a reductant, thereby hydrogenating the alkene to yield an alkane and water, and separating the alkane from the water to yield the alkane. The reductant includes a first metal and the catalyst includes a second metal.Type: ApplicationFiled: September 30, 2020Publication date: April 15, 2021Inventors: Kirtland Robinson, Ian Gould, Christiana Bockisch, Everett Shock, Hilairy Hartnett, Lynda B. Williams
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Patent number: 9458500Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: GrantFiled: June 8, 2013Date of Patent: October 4, 2016Assignee: Life Technologies CorporationInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Patent number: 9096898Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: GrantFiled: December 16, 2010Date of Patent: August 4, 2015Assignee: LIFE TECHNOLOGIES CORPORATIONInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20130295560Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: June 8, 2013Publication date: November 7, 2013Inventors: Peter Williams, Thomas J. Taylor, Daniel J.B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20130288235Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: May 14, 2013Publication date: October 31, 2013Inventors: Peter Williams, Thomas J. Taylor, Daniel J.B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20120258449Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: February 29, 2012Publication date: October 11, 2012Applicant: ARIZONA BOARD OF REGENTSInventors: Peter Williams, Thomas J. Taylor, Daniel J.B. Williams, Ian Gould, Mark A. Hayes
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Patent number: 8263364Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: GrantFiled: January 18, 2011Date of Patent: September 11, 2012Assignee: Arizona Board of RegentsInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Patent number: 8263365Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: GrantFiled: January 18, 2011Date of Patent: September 11, 2012Assignee: Arizona Board of RegentsInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Patent number: 8216514Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: GrantFiled: June 8, 2011Date of Patent: July 10, 2012Assignee: Arizona Board of RegentsInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20120015353Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: June 8, 2011Publication date: January 19, 2012Applicant: HELICOS BIOSCIENCES CORPORATIONInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20110294115Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: May 3, 2011Publication date: December 1, 2011Applicant: ARIZONA BOARD OF REGENTSInventors: Peter Williams, Thomas J. Taylor, Daniel J.B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20110183321Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: December 16, 2010Publication date: July 28, 2011Applicant: ARIZONA BOARD OF REGENTSInventors: Peter Williams, Thomas J. Taylor, Daniel J.B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20110183322Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: January 18, 2011Publication date: July 28, 2011Applicant: ARIZONA BOARD OF REGENTSInventors: Peter Williams, Thomas J. Taylor, Daniel J.B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20110183323Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: January 18, 2011Publication date: July 28, 2011Applicant: ARIZONA BOARD OF REGENTSInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Patent number: 7875440Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: GrantFiled: October 30, 2007Date of Patent: January 25, 2011Assignee: Arizona Board of RegentsInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20100209922Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: November 13, 2009Publication date: August 19, 2010Applicant: ARIZONA BOARD OF REGENTSInventors: PETER WILLIAMS, THOMAS J. TAYLOR, DANIEL J.B. WILLIAMS, IAN GOULD, MARK A. HAYES
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Patent number: 7645596Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA poly-merase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: GrantFiled: May 5, 2004Date of Patent: January 12, 2010Assignee: Arizona Board of RegentsInventors: Peter Williams, Thomas J. Taylor, Daniel J. B. Williams, Ian Gould, Mark A. Hayes
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Publication number: 20080213770Abstract: The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases, supplied individually and serially in a microfluidic system, to a reaction cell containing a template system comprising a DNA fragment of unknown sequence and an oligonucleotide primer. Incorporation of a nucleotide base into the template system can be detected by any of a variety of methods including but not limited to fluorescence and chemiluminescence detection. Alternatively, microcalorimetic detection of the heat generated by the incorporation of a nucleotide into the extending template system using thermopile, thermistor and refractive index measurements can be used to detect extension reactions.Type: ApplicationFiled: October 30, 2007Publication date: September 4, 2008Applicant: HELICOS BIOSCIENCES CORPORATIONInventors: Peter Williams, Thomas J. Taylor, Daniel J.B. Williams, Ian Gould, Mark A. Hayes