Patents by Inventor Ian H. Smith
Ian H. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240094233Abstract: The present invention relates to methods, devices and systems for associating consumable data with an assay consumable used in a biological assay. Provided are assay systems and associated consumables, wherein the assay system adjusts one or more steps of an assay protocol based on consumable data specific for that consumable. Various types of consumable data are described, as well as methods of using such data in the conduct of an assay by an assay system. The present invention also relates to consumables (e.g., kits and reagent containers), software, data deployable bundles, computer-readable media, loading carts, instruments, systems, and methods, for performing automated biological assays.Type: ApplicationFiled: July 18, 2023Publication date: March 21, 2024Inventors: Jacob N. WOHLSTADTER, Manish KOCHAR, Peter J. BOSCO, Ian D. CHAMBERLIN, Bandele JEFFREY-COKER, Eric M. JONES, Gary I. KRIVOY, Don E. KRUEGER, Aaron H. LEIMKUEHLER, Pei-Ming WU, Kim-Xuan NGUYEN, Pankaj OBEROI, Louis W. PANG, Jennifer PARKER, Victor PELLICIER, Nicholas SAMMONS, George SIGAL, Michael L. VOCK, Stanley T. SMITH, Carl C. STEVENS, Rodger D. OSBORNE, Kenneth E. PAGE, Michael T. WADE, Jon WILLOUGHBY, Lei WANG, Xinri CONG, Kin NG
-
Patent number: 5466710Abstract: The present invention provides a class of substituted bicyclooctanes of formula ##STR1## wherein R is a C.sub.2-10 non-aromatic hydrocarbyl optionally substituted by cyano, halo, C.sub.1-4 alkoxy, C.sub.1-4 haloalkoxy or S(O).sub.m R.sup.3 ; R.sup.1 and r.sup.2 are independently hydrogen, halo, a C.sub.1-3 aliphatic group optionally substituted, S(O).sub.m,R.sup.4, or R.sup.1 and R.sup.2 and the carbon atoms to which they are attached form a C.sub.5-7 carbocyclic ring optionally substituted by halo, or a C.sub.1-3 aliphatic or alkoxy group;A-X is a group:(i) A'C.tbd.CX in which A' is a C.sub.3-6 alkyl, alkenyl or alkynyl or a C.sub.3-10 cycloalkyl or cycloalkenyl group all optionally containing one to three hetero atoms.(ii) BX in which B is a group (CH.sub.2).sub.2 O or (CH.sub.2).sub.2 S(O).sub.n or a C.sub.2-6 aliphatic chain optionally containing one or two oxygen or sulphur atoms and/or double bonds and optionally further substituted;X is hydrogen, halo, SiR.sup.5 R.sup.6 R.sup.7 or SnR.sup.5 R.sup.6 R.Type: GrantFiled: October 6, 1993Date of Patent: November 14, 1995Assignee: Roussel UclafInventors: John B. Weston, John P. Larkin, Ian H. Smith
-
Patent number: 5371075Abstract: Bicyclo-[2,2,1]-heptanes, bicyclo-[2,2,2,]-octanes and bicyclo-[2,2,3]-nonanes having 2 or 3 ring hetero atoms selected from O, S and N, substituted at the 1-position by a 4-alkynylphenyl group and at the 4-position and optionally at the 3 and/or 5-position are valuable pesticides, particularly insecticides and acaracides. The compounds may be prepared by reacting an alkyne with the corresponding 4-iodophenyl substituted compound or by debromination of the corresponding 4-dibromomethylphenyl substituted compound.Type: GrantFiled: July 29, 1992Date of Patent: December 6, 1994Assignees: Roussel-Uclaf, University of CaliforniaInventors: John E. Casida, Christopher J. Palmer, John P. Larkin, Ian H. Smith
-
Patent number: 5204333Abstract: The present invention provides compounds of the formula (I): ##STR1## wherein R is a phenyl group, substituted fluorine atoms formulations containing them and their use in controlling pest infestation.Type: GrantFiled: February 24, 1992Date of Patent: April 20, 1993Inventors: John P. Larkin, John B. Weston, Ian H. Smith, Christopher J. Palmer, John E. Casida
-
Patent number: 5157029Abstract: Bicyclo-[2,2,1]-heptanes, bicyclo-[2,2,2]-octanes and bicyclo-[2,2,3]-nonanes having 2 or 3 ring hetero atoms selected from O, S and N, substituted at the 1-position by a 4-alkynylphenyl group and at the 4-position and optionally at the 3 and/or 5-position are valuable pesticides, particularly insecticides and acaracides. The compounds may be prepared by reacting an alkyne with the corresponding 4-iodophenyl substituted compound or by debromination of the corresponding 4-dibromomethylphenyl substituted compound.Type: GrantFiled: August 2, 1991Date of Patent: October 20, 1992Assignee: The Regents of the University of CaliforniaInventors: John E. Casida, Christopher J. Palmer, John P. Larkin, Ian H. Smith
-
Patent number: 5116862Abstract: The present invention provides a class of novel substituted bicyclooctanes which have pesticidal activity, particularly against arthropod pests. Pesticidal formulations containing the compounds of the formula (I), their use in the control of pests and methods for their preparation are also disclosed.Type: GrantFiled: July 21, 1988Date of Patent: May 26, 1992Assignee: The Wellcome Foundation LimitedInventors: John B. Weston, John P. Larkin, Ian H. Smith
-
Patent number: 5098929Abstract: A compound of the formula (I): ##STR1## wherein R is C.sub.2-10 alkyl, alkenyl or alkynyl, each optionally subsituted by or methyl substituted by cyano, C.sub.3-4 cycloalkyl, halo, C.sub.1-4 alkoxy or a group S(O)mR.sup.4 where R.sup.4 is C.sub.1-4 alkyl and m is O, 1 or 2, or R is C.sub.3-10 cycloalkyl, C.sub.4-10 cycloalkenyl or phenyl, each optionally substituted by C.sub.1-4 alkoxy, C.sub.1-3 alkyl, C.sub.2-4 alkynyl, halo, cyano or a group S(O)mR.sup.4 as defined hereinbefore; R.sup.1 is halo, C.sub.1-3 alkyl, C.sub.2-3 alkenyl or alkynyl each optionally substituted by halo, cyano, C.sub.1-4 alkoxy, alkyl carbalkoxy containing up to 6 carbon atoms, a group S(O)mR.sup.4 as defined hereinbefore or alkynyl substituted by tri-C.sub.1-4 alkylsilyl, or R.sup.1 is cyano, spiro-cyclopropyl, gem dimethyl, oxo or methylene optionally substituted by cyano or C.sub.1-3 alkyl optionally substituted by fluorine, or R.sup.1 and R and the carbon atoms to which they are attached form a C.sub.Type: GrantFiled: February 9, 1990Date of Patent: March 24, 1992Assignee: The Wellcome Foundation LimitedInventors: John P. Larkin, Ian H. Smith
-
Patent number: 5057504Abstract: Pesticidal bicyclo-octanes are of the formula ##STR1## where R is a substituted or unsubstituted aliphatic or aromatic group, R' and R.sup.3 are H or a substituted or unsubstituted aliphatic or aromatic group, R.sup.2 is a substituted or unsubstituted heterocyclic group containing at least one ring nitrogen and is preferably a 3- or 4- pyridyl group, Z is CH.sub.2 CH.sub.2, CH.sub.2 O--CH.sub.2 S or COCH.sub.2 or CH(OR.sup.5)CH.sub.2 where R.sup.5 is H, alkyl, acyl or carbamoyl at Y and Y' are O or S(O).sub.m where m is 0, 1 or 2.Various methods for their preparation are described.Type: GrantFiled: August 16, 1989Date of Patent: October 15, 1991Assignee: The Wellcome Foundation LimitedInventors: Malcolm H. Black, John A. Wyatt, John B. Weston, John P. Larkin, Ian H. Smith, David A. Pulman
-
Patent number: 5057508Abstract: Bicyclo-[2,2,1]-heptanes, bicyclo-[2,2,2]-octanes and bicyclo[2,2,3]-nonanes having 2 or 3 ring hetero atoms selected from O, S and N, substituted at the 1-position by a 4-alkynylphenyl group and at the 4-position and optionally at the 3 and/or 5-position are valuable pesticides, particularly insecticides and acaracides. The compounds may be prepared by reacting an alkyne with the corresponding 4-iodophenyl substituted compound or by debromination of the corresponding 4-dibromomethylphenyl substituted compound.Type: GrantFiled: February 20, 1990Date of Patent: October 15, 1991Assignee: The Regents of the University of CaliforniaInventors: John E. Casida, Christopher J. Palmer, John P. Larkin, Ian H. Smith
-
Patent number: 5026548Abstract: A surfactant for use as a viscosity reducing agent in chocolate, or an emulsifier, surfactant or foam stabilizer in the food and other industries is produced by extracting oats using an alcohol such as ethanol or propanol, extracting the alcohol extract with methanol and evaporating the methanol. The alcohol extraction may be preceded by extraction with a non-polar solvent such as hexane. A water-soluble surfactant can be produced by extracting the methanol extract with acetone and recovering the acetone-insoluble material.Type: GrantFiled: December 28, 1988Date of Patent: June 25, 1991Assignee: Cadbury Schweppes plcInventors: Roger Evans, Michael H. Jee, Nigel H. Sander, Ian H. Smith, Raymond K. Gibson
-
Patent number: 4965257Abstract: Bicyclo-[2,2,1]-heptanes, bicyclo-[2,2,2]-octanes and bicyclo-[2,2,3]-nonanes, having 2 or 3 ring hetero atoms selected from O, S and N, substituted at the 1-position by a 4-alkynylphenyl group and at the 4-position and optionally at the 3 and/or 5-position are valuable pesticides, particularly insecticides and acaracides. The compounds may be prepared by reacting an alkyne with the corresponding 4-iodophenyl substituted compounds or by debromination of the corresponding 4-dibromomethylphenyl substituted compound.Type: GrantFiled: July 24, 1989Date of Patent: October 23, 1990Assignee: The Regents of the University of CaliforniaInventors: John E. Casida, Christopher J. Palmer, John P. Larkin, Ian H. Smith
-
Patent number: 4942173Abstract: The present invention relates to a compound of the formula (I): ##STR1## wherein R is C.sub.2-10 alkyl, alkenyl or alkynyl, each optionally substituted by or methyl substituted by cyano, C.sub.3-4 cycloalkyl, halo, C.sub.1-4 alkoxy or a group S(O)m R.sup.4 where R.sup.4 is C.sub.1-4 alkyl and m is 0, 1 or 2, or Ris C.sub.3-10 cycloalkyl, C.sub.4-10 cycloalkenyl or phenyl, each optionally substituted by C.sub.1-4 alkoxy, C.sub.1-3 alkyl, C.sub.2-4 alkynyl, halo, cyano or a group S(O)m R.sup.4 as defined hereinbefore; R.sup.1 is halo, C.sub.1-3 alkyl, C.sub.2-3 alkenyl or alkynyl each optionally substituted by halo, cyano, C.sub.1-4 alkoxy, alkyl carbalkoxy containing up to 6 carbon atoms, a group S(O)m R.sup.4 as defined hereinbefore or alkynyl substituted by tri-C.sub.1-4 alkylsilyl, or R.sup.1 is cyano, spiro-cyclopropyl, gem dimethyl, gem dicyano, gem diethynyl, oxo or methylene optionally substituted by cyano of C.sub.1-3 alkyl optionally substituted by fluorine, or R.sup.Type: GrantFiled: February 24, 1989Date of Patent: July 17, 1990Assignee: The Regents of the University of CaliforniaInventors: John E. Casida, Christopher J. Palmer, John P. Larkin, Ian H. Smith