Patents by Inventor Ian Harrow

Ian Harrow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of PDE11A activity
    Publication number: 20060121550
    Abstract: The invention provides genetically modified non-human mammals and genetically modified animal cells containing a functionally disrupted PDE11A gene. Also provided by the invention are methods of screening for agents that modulate PDE11A to modulate spermatogenesis, methods of treating mammals to modulate spermatogenesis, and methods of modulating cAMP and cGMP signal transduction in cells that express PDE11A. The invention also provides agents and methods relating to the effect of PDE11A modulation (i.e. PDE11A inhibition or stimulation) on ex vivo spermatozoa capacitation and PDE11A stimulation on in vivo spermatozoa capacitation. The invention also relates to the effect of PDE11A modulation on male pro-fertility and female sexual dysfunction (FSD), specifically female sexual arousal disorder (FSAD), female orgasmic disorder (FOD), hypoactive sexual desire disorder (HSDD) or sexual pain disorders.
    Type: Application
    Filed: April 29, 2002
    Publication date: June 8, 2006
    Inventors: Martyn Burslem, Ian Harrow, Jeremy Lanfear, Stephen Phillips, Christopher Wayman
  • Antibodies specifically binding cyclic nucleotide PDEs
    Publication number: 20030092156
    Abstract: The invention provides human cyclic nucleotide phosphodiesterases (HSPDE10A), polynucleotides that encode HSPDE10A, and antibodies that specifically bind HSPDE10A. The invention also provides expression vectors, host cells, agonists, and antagonists and methods for diagnosing or treating disorders associated with expression of HSPDE10A.
    Type: Application
    Filed: March 7, 2002
    Publication date: May 15, 2003
    Inventors: Stephen C. Phillips, Ian Harrow, Jerry Lanfear, Lindsay Fawcett, Olga Bandman
  • Human cyclic nucleotide PDES
    Patent number: 6416991
    Abstract: The invention provides human cyclic nucleotide phosphodiesterases (HSPDE10A) and polynucleotides which identify and encode HSPDE10A. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists and methods for diagnosing or treating disorders associated with expression of HSPDE10A.
    Type: Grant
    Filed: June 14, 2000
    Date of Patent: July 9, 2002
    Assignee: Incyte Genomics, Inc.
    Inventors: Stephen C. Phillips, Jerry Lanfear, Lindsay Fawcett, Olga Bandman, Ian Harrow