Patents by Inventor Ian Holmes

Ian Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250066416
    Abstract: The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.
    Type: Application
    Filed: October 30, 2024
    Publication date: February 27, 2025
    Inventors: David Jackson, Ian Holmes, Weiguang Zeng, Christophe Demaison
  • Publication number: 20250042931
    Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: October 10, 2024
    Publication date: February 6, 2025
    Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Robert M. BURK, Marc GLEESON, Mark Richard STEWART, Jonathan DUNN, Alexander James NICHOLLS
  • Patent number: 12195557
    Abstract: The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: January 14, 2025
    Assignee: AXELIA ONCOLOGY PTY LTD
    Inventors: David Jackson, Ian Holmes, Weiguang Zeng, Christophe Demaison
  • Patent number: 12157777
    Abstract: The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: December 3, 2024
    Assignee: AXELIA ONCOLOGY PTY LTD
    Inventors: David Jackson, Ian Holmes, Weiguang Zeng, Christophe Demaison
  • Patent number: 12017979
    Abstract: The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.
    Type: Grant
    Filed: March 23, 2023
    Date of Patent: June 25, 2024
    Assignee: ENA Respiratory Pty Ltd
    Inventors: Ian Holmes, Weiguang Zeng, David Jackson, Christophe Demaison, Grant McLachlan
  • Publication number: 20240158375
    Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: October 20, 2021
    Publication date: May 16, 2024
    Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Robert M. BURK, Marc GLEESON, Mark Richard STEWART, Soultana KATSINA
  • Publication number: 20230399317
    Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: October 20, 2021
    Publication date: December 14, 2023
    Inventors: Charles BOSWORTH, Mark Richard STEWART, Hila BARASH, Nicholas Andrew CHAPMAN, Robert M. BURK, Ian HOLMES, Marc GLEESON, Yair ALSTER, Omer RAFAELI, Jonathan DUNN
  • Publication number: 20230357207
    Abstract: Described herein are compositions and methods for the treatment of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious disease of the anterior surface of the eye. Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: March 8, 2023
    Publication date: November 9, 2023
    Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Marc GLEESON, Mark Richard STEWART, Robert M. BURK, Jonathan DUNN, Nicholas CHAPMAN
  • Publication number: 20230348517
    Abstract: Described herein are compositions and methods for the treatment of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory/infections disease of the anterior surface of the eye. Said compositions and methods comprise keratolytic conjugate which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eye, ocular surface or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: March 6, 2023
    Publication date: November 2, 2023
    Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Marc GLEESON, Mark Richard STEWART, Jonathan DUNN
  • Publication number: 20230288901
    Abstract: In a production line where various operations have to be performed on a unit that is conveyed through or assembled in the line, a control system for a set of actuators is provided that operates in discrete steps to carry out movement in a machine and is required to synchronize at points in speed and position. A controller is provided for each actuator, and a coordinator configured to determine or receive the position of the actuators and to receive or generate data concerning a waypoint, being positions and corresponding speeds for the actuators. The controllers are configured to change the speed of the actuators, and the coordinator starts the movement of at least one actuator on the basis of a point reached by another actuator, so as to achieve the desired synchronization.
    Type: Application
    Filed: May 20, 2021
    Publication date: September 14, 2023
    Inventor: Ian HOLMES
  • Publication number: 20230257345
    Abstract: The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.
    Type: Application
    Filed: March 23, 2023
    Publication date: August 17, 2023
    Inventors: Ian Holmes, Weiguang Zeng, David Jackson, Christophe Demaison, Grant McLachlan
  • Patent number: 11643429
    Abstract: Described herein are compositions and methods for the treatment of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory/infections disease of the anterior surface of the eye. Said compositions and methods comprise keratolytic conjugate which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eye, ocular surface or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: May 9, 2023
    Assignee: AZURA OPHTHALMICS LTD.
    Inventors: Ian Holmes, Yair Alster, Hila Barash, Charles Bosworth, Omer Rafaeli, Marc Gleeson, Mark Richard Stewart, Jonathan Dunn
  • Patent number: 11634411
    Abstract: Described herein are compositions and methods for the treatment of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious disease of the anterior surface of the eye. Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: April 25, 2023
    Assignee: AZURA OPHTHALMICS LTD.
    Inventors: Ian Holmes, Yair Alster, Hila Barash, Charles Bosworth, Omer Rafaeli, Marc Gleeson, Mark Richard Stewart, Robert M. Burk, Jonathan Dunn, Nicholas Chapman
  • Publication number: 20220388950
    Abstract: The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.
    Type: Application
    Filed: June 26, 2020
    Publication date: December 8, 2022
    Inventors: Ian Holmes, Weiguang Zeng, David Jackson, Christophe Demaison, Grant Mclachlan
  • Publication number: 20220332748
    Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: April 5, 2021
    Publication date: October 20, 2022
    Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Robert M. BURK, Marc GLEESON, Mark Richard STEWART, Jonathan DUNN, Alexander James NICHOLLS
  • Publication number: 20220332749
    Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: June 15, 2022
    Publication date: October 20, 2022
    Inventors: Ian HOLMES, Yair ALSTER, Hila EPSTEIN-BARASH, Charles BOSWORTH, Omer RAFAELI, Robert M. BURK, Marc GLEESON, Mark Richard STEWART, Jonathan DUNN, Alexander James NICHOLLS
  • Patent number: 11459351
    Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Grant
    Filed: April 5, 2021
    Date of Patent: October 4, 2022
    Assignee: AZURA OPHTHALMICS LTD.
    Inventors: Ian Holmes, Yair Alster, Hila Barash, Charles Bosworth, Omer Rafaeli, Robert M. Burk, Marc Gleeson, Mark Richard Stewart, Jonathan Dunn, Alexander James Nicholls
  • Publication number: 20210230205
    Abstract: Described herein are compositions and methods for the treatment of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory/infections disease of the anterior surface of the eye. Said compositions and methods comprise keratolytic conjugate which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eye, ocular surface or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: April 5, 2021
    Publication date: July 29, 2021
    Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Marc GLEESON, Mark Richard STEWART, Jonathan DUNN
  • Publication number: 20210230217
    Abstract: The present invention relates to TLR2 agonist compounds and their compositions, and the use of such compounds and compositions in the prevention and/or treatment of respiratory infections, or diseases or conditions associated with viral or bacterial infections.
    Type: Application
    Filed: December 21, 2018
    Publication date: July 29, 2021
    Inventors: David Jackson, Ian Holmes, Weiguang Zeng, Christophe Demaison
  • Publication number: 20210107899
    Abstract: Described herein are compositions and methods for the treatment of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious disease of the anterior surface of the eye. Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.
    Type: Application
    Filed: December 4, 2020
    Publication date: April 15, 2021
    Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Marc GLEESON, Mark Richard STEWART, Robert M. BURK, Jonathan DUNN, Nicholas CHAPMAN