Patents by Inventor Ian J. Macrae

Ian J. Macrae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified dicer polypeptide and methods of use thereof
    Patent number: 8440430
    Abstract: A modified Dicer polypeptide is provided, which modified Dicer polypeptide exhibits enhanced catalytic activity. Also provided is a method for producing small regulatory RNAs from a dsRNA, involving contacting a dsRNA with a subject modified Dicer. Small regulatory RNAs produced by a subject method find use in a variety of applications, including research and therapeutic applications.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: May 14, 2013
    Assignee: The Regents of the University of California
    Inventors: Jennifer Doudna, Enbo Ma, Ian J. MacRae
  • Modified Dicer Polypeptide and Methods of Use Thereof
    Publication number: 20110117610
    Abstract: A modified Dicer polypeptide is provided, which modified Dicer polypeptide exhibits enhanced catalytic activity. Also provided is a method for producing small regulatory RNAs from a dsRNA, involving contacting a dsRNA with a subject modified Dicer. Small regulatory RNAs produced by a subject method find use in a variety of applications, including research and therapeutic applications.
    Type: Application
    Filed: March 18, 2009
    Publication date: May 19, 2011
    Inventors: Jennifer Doudna, Enbo Ma, Ian J. Macrae