Abstract: Embodiments include therapeutic small molecules for use in treating addiction and neurological disorder by stimulating neuroplasticity. The therapeutic small molecule can increase neuroplasticity and improve neural function by affecting upstream regulators of FOS, JUN, BDNF, CDC42 and CCL2. The therapeutic small molecule can also aid in reduction of Amyloid plaques via binding with amyloid beta (a4).

Abstract: Applicants have identified biomarkers that can be expressed at elevated levels in subjects who are prone to developing diabetes. The biomarkers can include misfolded proinsulin, correctly folded proinsulin, follistatin, hemoglobin A1c, C-Reactive Protein, Interleukin 18 and Interleukin 1 Receptor Antagonist, glutamic decarboxylase autoantibodies, islet cell autoantibodies, insulin autoantibodies, zinc transporter protein autoantibodies, insulinoma associated-2 autoantibodies, C-reactive protein, protectin D1, a lipoxin and a maresin. Embodiments include methods of predicting or assessing a subject's risk of developing diabetes before onset of the disease. The methods can also determine the progression and/or prognosis of diabetes. A subject who is at risk of developing the disease can be any of Type 1, Type 1.5 or Type 2 diabetes.

Abstract: An apparatus is configured to monitor a plurality of layers of a battery layer stack during manufacturing. The apparatus includes at least one X-ray source configured to generate X-rays with X-ray energies that exhibit contrast of transmission through the plurality of layers of the battery layer stack. The at least one X-ray source is configured to face a first side of the battery layer stack. The apparatus further includes at least one sensor configured to detect the X-rays transmitted through the plurality of layers. The at least one sensor is configured to face a second side of the battery layer stack.

Abstract: The disclosure generally describes computer-implemented methods, software, and systems for generating a health recommendation. A computer-implemented method includes receiving genetic data and user data of a user. The genetic data is processed to generate vector representations of a fixed size by using an unsupervised learning algorithm. Health risk features are extracted from the vector representations by using a multi-layer convolutional neural network. Dietary conditions associated with the health risk features are determined and used to generate the health recommendation. The health recommendation is displayed for the user.

Abstract: The disclosure generally describes computer-implemented methods, software, and systems for generating a health recommendation. A computer-implemented method includes receiving genetic data and user data of a user. The genetic data is processed to generate vector representations of a fixed size by using an unsupervised learning algorithm. Health risk features are extracted from the vector representations by using a multi-layer convolutional neural network. Dietary conditions associated with the health risk features are determined and used to generate the health recommendation. The health recommendation is displayed for the user.

Abstract: Visibility of a scan laser light pattern or an aiming laser light pattern on a symbol to be read by a hand-held, electro-optical reader is enhanced by directing laser light having a laser wavelength in the laser light pattern to the symbol, configuring an optical element to be transmissive to the laser light of the same laser wavelength, supporting the optical element by the reader, moving the optical element from a stored position to a deployed position, and viewing the laser light pattern on the symbol through the optical element in the deployed position.

Abstract: A sealed electrical enclosure used in hazardous locations for enclosing electrical components having a bottom housing and a top housing with a serrated joint formed therebetween, the bottom housing adapted to receive one or more electrical components, a first metal bus extending from a point internal to the bottom housing through a first end wall to a point external thereto, and a second metal bus extending from a point internal to the bottom housing through a second end wall to a point external to thereto, where the first and second metal buses are adapted to contact first and second electrical terminals of an electrical component when placed within the bottom housing, wherein the top housing is removably secured to the bottom housing to allow for removal and replacement of an electrical component within the housing.

Abstract: The present disclosure includes an adapter and associated method of use for mobile unit (MU) charging and communication that enables multiple connector types to be utilized with a single charger or charging station. The adapter enables standardization of a connector scheme on newer MUs while maintaining compatibility with current or older MU devices. Specifically, the adapter resides between the MU and a charging device or station. The adapter may include various connector features mimicking connectors of various different MUs, thus allowing it to interface with a device of a different connector design. Advantageously, the adapter enables enterprises to deploy various cradles throughout facilities and achieves universal connections for a plurality of different MUs. In an exemplary embodiment, the adapter provides connectivity between various MUs and their associated cradles and a hook and pivoting latching system.

Abstract: A radio frequency identification (RFID) reader for, and method of, reading an RFID tag to obtain data in both handheld and hands-free modes of operation, include all RFID module supported by the reader and including an antenna for propagating an electromagnetic field over a range, and a controller for varying the range of the antenna to be different in each mode. The antenna has a full range, preferably by default, in the handheld mode, and the controller is operative, preferably automatically, for decreasing the full range to a restricted range in the hands-free mode.

Abstract: A sealed electrical enclosure used in hazardous locations for enclosing electrical components having a bottom housing and a top housing with a serrated joint formed therebetween, the bottom housing adapted to receive one or more electrical components, a first metal bus extending from a point internal to the bottom housing through a first end wall to a point external thereto, and a second metal bus extending from a point internal to the bottom housing through a second end wall to a point external to thereto, where the first and second metal buses are adapted to contact first and second electrical terminals of an electrical component when placed within the bottom housing, wherein the top housing is removably secured to the bottom housing to allow for removal and replacement of an electrical component within the housing.

Abstract: Visibility of a scan laser light pattern or an aiming laser light pattern on a symbol to be read by a hand-held, electro-optical reader is enhanced by directing laser light having a laser wavelength in the laser light pattern to the symbol, configuring an optical element to be transmissive to the laser light of the same laser wavelength, supporting the optical element by the reader, moving the optical element from a stored position to a deployed position, and viewing the laser light pattern on the symbol through the optical element in the deployed position.

Abstract: The present disclosure includes an adapter and associated method of use for mobile unit (MU) charging and communication that enables multiple connector types to be utilized with a single charger or charging station. The adapter enables standardization of a connector scheme on newer MUs while maintaining compatibility with current or older MU devices. Specifically, the adapter resides between the MU and a charging device or station. The adapter may include various connector features mimicking connectors of various different MUs, thus allowing it to interface with a device of a different connector design. Advantageously, the adapter enables enterprises to deploy various cradles throughout facilities and achieves universal connections for a plurality of different MUs. In an exemplary embodiment, the adapter provides connectivity between various MUs and their associated cradles and a hook and pivoting latching system.

Abstract: A sealed electrical enclosure used in hazardous locations for enclosing circuit breakers having a bottom housing and a top housing with a labyrinth seal or joint formed therebetween, the bottom housing adapted to receive one or more circuit breakers, a first metal bus extending from a point internal to the bottom housing through a first end wall to a point external thereto, and a second metal bus extending from a point internal to the bottom housing through a second end wall to a point external to thereto, where the first and second metal buses are adapted to contact first and second electrical terminals of a circuit breaker when placed within the bottom housing, and a first vent positioned on the top housing for dissipating pressure buildup, wherein the top housing is removably secured to the bottom housing to allow for removal and replacement of a circuit breakers within the housing.

Abstract: A sealed electrical enclosure used in hazardous locations for enclosing circuit breakers having a bottom housing and a top housing with a labyrinth seal or joint formed therebetween, the bottom housing adapted to receive one or more circuit breakers, a first metal bus extending from a point internal to the bottom housing through a first end wall to a point external thereto, and a second metal bus extending from a point internal to the bottom housing through a second end wall to a point external to thereto, where the first and second metal buses are adapted to contact first and second electrical terminals of a circuit breaker when placed within the bottom housing, and a first vent positioned on the top housing for dissipating pressure buildup, wherein the top housing is removably secured to the bottom housing to allow for removal and replacement of a circuit breakers within the housing.

Abstract: A sealed electrical enclosure used in hazardous locations for enclosing circuit breakers having a bottom housing and a top housing with a labyrinth seal or joint formed therebetween, the bottom housing adapted to receive one or more circuit breakers, a first metal bus extending from a point internal to the bottom housing through a first end wall to a point external thereto, and a second metal bus extending from a point internal to the bottom housing through a second end wall to a point external to thereto, where the first and second metal buses are adapted to contact first and second electrical terminals of a circuit breaker when placed within the bottom housing, and a first vent positioned on the top housing for dissipating pressure buildup, wherein the top housing is removably secured to the bottom housing to allow for removal and replacement of a circuit breakers within the housing.

Abstract: A radio frequency identification (RFID) reader for, and method of, reading an RFID tag to obtain data in both handheld and hands-free modes of operation, include all RFID module supported by the reader and including an antenna for propagating an electromagnetic field over a range, and a controller for varying the range of the antenna to be different in each mode. The antenna has a full range, preferably by default, in the handheld mode, and the controller is operative, preferably automatically, for decreasing the full range to a restricted range in the hands-free mode.

Abstract: A sealed electrical enclosure used in hazardous locations for enclosing circuit breakers having a bottom housing and a top housing with a labyrinth seal or joint formed therebetween, the bottom housing adapted to receive one or more circuit breakers, a first metal bus extending from a point internal to the bottom housing through a first end wall to a point external thereto, and a second metal bus extending from a point internal to the bottom housing through a second end wall to a point external to thereto, where the first and second metal buses are adapted to contact first and second electrical terminals of a circuit breaker when placed within the bottom housing, and a first vent positioned on the top housing for dissipating pressure buildup, wherein the top housing is removably secured to the bottom housing to allow for removal and replacement of a circuit breakers within the housing.

Abstract: Compounds of general formula (I) wherein D, E, R1, R2, R3, R4, R5, R6 and R7 are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Abstract: A docking station for a portable electronic device comprises a housing forming a first cradle receiving slot, the housing including a first housing connector within the first cradle receiving slot in combination with a first cradle shell inerrable into the first cradle receiving slot, the first cradle shell being sized and shaped to receive a first portable electronic device therein, the first cradle shell including a first shell inner connector positioned on a device receiving side of the cradle shell so that, when a first portable electronic device is received in the first cradle shell, the first shell inner connector is aligned with a connector of the first portable electronic device and a first shell outer shell connector on a housing facing surface of the first cradle shell, the first shell outer connector being positioned so that, when the first cradle shell is inserted into the first cradle receiving slot, the first shell outer connector aligns with the first housing connector.