Abstract: The present invention provides a process for generation of genetically modified T cells, T cell subsets and/or T cell progenitors comprising the steps: a) providing a cell sample comprising T cells, T cell subsets and/or T cell progenitors b) preparation of the cell sample by centrifugation c) magnetic separation of the T cells, T cell subsets and/or T cell progenitors d) activation of the enriched T cells, T cell subsets and/or T cell progenitors using modulatory agents e) genetic modification of the T cells, T cell subsets and/or T cell progenitors f) expansion of the genetically modified T cells, T cell subsets and/or T cell progenitors in a cultivation chamber g) washing of the cultured T cells, T cell subsets and/or T cell progenitors characterized in that all steps are performed in a closed and sterile cell culture system.

Abstract: A method of detecting a change in angular position of a camera. A plurality of frames captured by the camera is received, each frame being associated with brightness and acceleration metadata. The brightness metadata is associated with a frame being representative of brightness of a scene captured by the frame. A contiguous set of candidate panning motion frames is selected from the plurality of frames, based on similarity of acceleration characteristics, to determine a change of brightness metadata in the selected contiguous set of frames. An angular movement score is determined for the selected contiguous set of frames using the change of brightness metadata. A change in the angular position of the camera is detected based on the angular movement score to adjust a manner in which the plurality of frames is displayed by a display device coupled with the camera.

Abstract: Techniques are disclosed for detection-based wakeup of detection devices. A method may include generating a mapping that includes entries. Each entry may associate a respective detection result of a first detection device with a respective detection result of a second detection device. The method may further include transitioning the second detection device to a first power mode upon completing the generating. The method may further include determining, by the first detection device, that a first object of a first object type is detected based on the mapping. The method may further include transitioning the second detection device out of the first power mode when the first object of the first object type is determined to be detected. The method may further include performing, by the second detection device, at least one action based on the first object. Related systems and devices are also disclosed.

Abstract: A system and method for the detection of bacteria on a sample, utilizes spectroscopic analysis of the sample and the fluorescent properties of bacteria or other substance(s) or matter associated with the bacteria to identify the presence of bacteria on the sample. A detector analyses light emitted from the sample in response to illumination. The detector 5 is arranged to analyze the emission spectra across two wavebands, a first waveband containing the wavelengths associated with the fluorescent properties of the bacterial species or other substance or matter to be detected, and a second waveband excluding these wavelengths but also having an overlapping region with the first waveband.

Abstract: A method of compositing layers by grouping the layers into a foreground group and a background group; identifying independent instructions of compositing model for execution independently from the background group and dependent instructions requiring a compositing output of a background layer in order to composite foreground layers; executing the independent instructions on the foreground layers in parallel with compositing the background layers, a first independent instruction storing a corresponding result in a first buffer and a second independent instruction storing a corresponding result in a second buffer; executing a dependent instruction by updating the second buffer using the background compositing output; and determining a compositing output for the foreground group dependent upon contents of the first buffer and the updated second buffer.

Abstract: The present invention provides a process for generation of genetically modified T cells, T cell subsets and/or T cell progenitors comprising the steps: a) providing a cell sample comprising T cells, T cell subsets and/or T cell progenitors b) preparation of the cell sample by centrifugation c) magnetic separation of the T cells, T cell subsets and/or T cell progenitors d) activation of the enriched T cells, T cell subsets and/or T cell progenitors using modulatory agents e) genetic modification of the T cells, T cell subsets and/or T cell progenitors f) expansion of the genetically modified T cells, T cell subsets and/or T cell progenitors in a cultivation chamber g) washing of the cultured T cells, T cell subsets and/or T cell progenitors characterized in that all steps are performed in a closed and sterile cell culture system.

Abstract: The invention relates to a process for generation of genetically modified stem cells comprising the steps a) providing a cell sample in suspension comprising stem cells in a centrifugation chamber comprising a base plate and cover plate connected by a cylinder b) adjusting the volumetric concentration of stem cells in the cell sample to at least 1×105 stem cells per mL cell sample by centrifugation c) introducing viral and/or non-viral vectors to the centrifugation chamber for genetically modifying the stem cells d) adjusting the spatial concentration of stem cells in the centrifugation chamber by rotating the centrifugation chamber at a speed where the cell sample is located at the outermost 35% of the radius of the base plate of the centrifugation chamber, thereby inducing gene modification of the stem cells.

Abstract: A method of compositing layers by grouping the layers into a foreground group and a background group; identifying independent instructions of compositing model for execution independently from the background group and dependent instructions requiring a compositing output of a background layer in order to composite foreground layers; executing the independent instructions on the foreground layers in parallel with compositing the background layers, a first independent instruction storing a corresponding result in a first buffer and a second independent instruction storing a corresponding result in a second buffer; executing a dependent instruction by updating the second buffer using the background compositing output; and determining a compositing output for the foreground group dependent upon contents of the first buffer and the updated second buffer.

Abstract: A computer implemented method to modify an intermediate representation of graphics data written in a page description language is described. The method renders the graphics data to produce a print preview representation stored as intermediate graphics data in an intermediate graphics format. A modifying operation for modifying graphics content of the print preview representation is detected, and the method determines whether the print preview representation contains information about the graphics data required to perform the modifying operation based on a class of the modifying operation and a content of the print preview representation affected by the detected modifying operation. Where the print preview representation contains information required to perform the modifying operation, the print preview representation is modified, and otherwise the method utilizes the graphics data written in the page description language to apply the modifying operation.

Abstract: A process for increasing the hydrogen content of a synthesis gas including hydrogen and carbon oxides and having a carbon monoxide content ?45 mole % on a dry-gas basis, including the steps of: (i) combining the synthesis gas with steam to form a steam-enriched feed gas mixture (ii) passing the feed gas mixture at an inlet temperature in the range 220-370° C. over an iron-based water-gas shift catalyst to form a hydrogen-enriched shifted gas mixture having a carbon monoxide content 10 mole % on a dry gas basis, and (iii) recovering the hydrogen-enriched shifted gas mixture, where a portion of the hydrogen-enriched shifted gas mixture is recycled to the feed gas mixture.

Abstract: Disclosed is a method of processing a print job, the print job being received in a page description language format. The method identifies a number of print heads on a printer targeted for printing said print job. The method processes the print job in the page description language format to produce a plurality of intermediate jobs, in which a number of the intermediate jobs is determined by the number of print heads. The intermediate jobs have an intermediate format between the page description language format and a rasterized image format. The method renders each of a plurality of intermediate jobs to a rasterized image in a renderer associated with each of the print heads independently of one another and external input.

Abstract: A system and method for the detection of bacteria on a sample, utilises spectroscopic analysis of the sample and the fluorescent properties of bacteria or other substance(s) or matter associated with the bacteria to identify the presence of bacteria on the sample. A detector analyses light emitted from the sample in response to illumination. The detector 5 is arranged to analyse the emission spectra across two wavebands, a first waveband containing the wavelengths associated with the fluorescent properties of the bacterial species or other substance or matter to be detected, and a second waveband excluding these wavelengths but also having an overlapping region with the first waveband.

Abstract: A computer implemented method to modify an intermediate representation of graphics data written in a page description language is described. The method renders the graphics data to produce a print preview representation stored as intermediate graphics data in an intermediate graphics format. A modifying operation for modifying graphics content of the print preview representation is detected, and the method determines whether the print preview representation contains information about the graphics data required to perform the modifying operation based on a class of the modifying operation and a content of the print preview representation affected by the detected modifying operation. Where the print preview representation contains information required to perform the modifying operation, the print preview representation is modified, and otherwise the method utilises the graphics data written in the page description language to apply the modifying operation.

Abstract: The invention relates to a process for generation of genetically modified stem cells comprising the steps a) providing a cell sample in suspension comprising stem cells in a centrifugation chamber comprising a base plate and cover plate connected by a cylinder b) adjusting the volumetric concentration of stem cells in the cell sample to at least 1×105 stem cells per mL cell sample by centrifugation c) introducing viral and/or non-viral vectors to the centrifugation chamber for genetically modifying the stem cells d) adjusting the spatial concentration of stem cells in the centrifugation chamber by rotating the centrifugation chamber at a speed where the cell sample is located at the outermost 35% of the radius of the base plate of the centrifugation chamber, thereby inducing gene modification of the stem cells.

Abstract: A process for increasing the hydrogen content of a synthesis gas including hydrogen and carbon oxides and having a carbon monoxide content?45 mole % on a dry-gas basis, including the steps of: (i) combining the synthesis gas with steam to form a steam-enriched feed gas mixture (ii) passing the feed gas mixture at an inlet temperature in the range 220-370° C. over an iron-based water-gas shift catalyst to form a hydrogen-enriched shifted gas mixture having a carbon monoxide content?10 mole % on a dry gas basis, and (iii) recovering the hydrogen-enriched shifted gas mixture, where a portion of the hydrogen-enriched shifted gas mixture is recycled to the feed gas mixture.

Abstract: A process for increasing the hydrogen content of a synthesis gas including hydrogen and carbon oxides and having a carbon monoxide content 45 mole % on a dry-gas basis, including the steps of: (i) combining the synthesis gas with steam to form a steam-enriched feed gas mixture (ii) passing the feed gas mixture at an inlet temperature in the range 220-370° C. over an iron-based water-gas shift catalyst to form a hydrogen-enriched shifted gas mixture having a carbon monoxide content 10 mole % on a dry gas basis, and (iii) recovering the hydrogen-enriched shifted gas mixture, where a portion of the hydrogen-enriched shifted gas mixture is recycled to the feed gas mixture.

Abstract: A process for increasing the hydrogen content of a synthesis gas including hydrogen and carbon oxides and having a carbon monoxide content ?45 mole % on a dry-gas basis, including the steps of: (i) combining the synthesis gas with steam to form a steam-enriched feed gas mixture (ii) passing the feed gas mixture at an inlet temperature in the range 220-370° C. over an iron-based water-gas shift catalyst to form a hydrogen-enriched shifted gas mixture having a carbon monoxide content ?10 mole % on a dry gas basis, and (iii) recovering the hydrogen-enriched shifted gas mixture, where a portion of the hydrogen-enriched shifted gas mixture is recycled to the feed gas mixture.

Abstract: A material for bonding a first wafer to a second wafer, which includes an insulating adhesive with conductive particles embedded in the adhesive substance. When the adhesive is applied and melted or fused, and pressure is applied between the first wafer and the second wafer, the first wafer approaches the second wafer until a minimum separation is reached, defined by a dimension of the conductive particles. Each of the first wafer and the second wafer may have circuitry formed thereon, and the conductive particles may form a conductive path between the circuitry on one wafer and the circuitry on the other wafer. Advantageously, the high fusing temperature required by the insulating adhesive may also serve to activate a getter material, formed in the device cavity between the first wafer and the second wafer.

Abstract: An improved method is provided for fabricating a polarisation rotator in a rib waveguide having a propagation axis and opposite side walls. The method includes etching a pit in the substrate surface to form a recess in one of the side walls of the waveguide, during formation of the waveguide on the substrate surface, so as to provide an asymmetric waveguide section for imparting polarisation rotation to radiation propagated along the propagation axis. Preferably the pit is formed by a wet etching step forming an upper side surface within the recess that is inclined relative the waveguide side walls, and the waveguide side walls are formed by a dry etching step to extend perpendicularly to the substrate surface. In addition the dry etching step forms a lower side surface adjoining the upper side surface within the recess and tilted relative to the upper side surface.

Abstract: A photonic integrated device having a substrate layer, epitaxial layers formed on said substrate layer and a guiding layer formed by one of the epitaxial layers. An optical waveguide is formed within the guiding layer. In the waveguide are a splitter (4) having at least two outputs, each output being transmitted to a Mach-Zehnder modulator (6, 8), the phase of the output of at least one modulator being shiftable, the signals being recombined to provide an optical phase shift key (PSK) output (14) wherein a trench is etched into the substrate layer between each pair of modulators to isolate the modulators from one another.