Abstract: A system (1) for calibrating an image capture device (2) mounted on a motor vehicle for offset from an ideal position and an ideal angular orientation while the vehicle is moving comprises selecting an image (12) in a captured image frame (10) of a stationary object relative to the motor vehicle, which is capable of being tracked through a plurality of successively captured image frames (14a,14d), predicting the locations at which the target image (12b) should appear in the respective successively captured image frames (14a,14d), comparing the actual location of the target image (12a) in the respective successively captured image frames (14a,14d) with the respective predicted locations (12b) and determining calibration values for the camera (2) from the results of the comparison, in the event that the actual (12a) and predicted locations (12b) of the target image in the respective image frames (14a,14d) do not coincide.

Abstract: A system (1) for calibrating an image capture device (2) mounted on a motor vehicle for offset from an ideal position and an ideal angular orientation while the vehicle is moving comprises selecting an image (12) in a captured image frame (10) of a stationary object relative to the motor vehicle, which is capable of being tracked through a plurality of successively captured image frames (14a,14d), predicting the locations at which the target image (12b) should appear in the respective successively captured image frames (14a,14d), comparing the actual location of the target image (12a) in the respective successively captured image frames (14a,14d) with the respective predicted locations (12b) and determining calibration values for the camera (2) from the results of the comparison, in the event that the actual (12a) and predicted locations (12b) of the target image in the respective image frames (14a,14d) do not coincide.

Abstract: Nanoparticles are prepared from a colloidal system comprising a continuous phase and micelles, the micelles comprising surfactant material. A microemulsion is formed by admixing the colloidal system with a solution of an active material, such as a medicament, dissolved in a solvent wherein the solution forms a disperse phase with the micelles of surfactant material. At least the dispersed phase is quenched to a solid state and the continuous phase and solvent are removed to produce the nanoparticles. The nanoparticles can be incorporated in an aerosol composition suitable for deep lung delivery by means of a metered dose inhaler.