Patents by Inventor Ian Kirby

Ian Kirby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8940303
    Abstract: Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: January 27, 2015
    Assignee: Glaxo Group Limited
    Inventors: Ian Kirby, Alex H. Taylor, Thomas Matthew Webb, Yu Xue
  • Patent number: 8916695
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanizing antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: December 23, 2014
    Assignee: Glaxo Group Limited
    Inventors: Gary Peter Bembridge, Chun-Wa Chung, Maria Feeney, Susannah Karen Ford, Ian Kirby, Ruth McAdam
  • Publication number: 20140201856
    Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: September 27, 2013
    Publication date: July 17, 2014
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20140201854
    Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: September 27, 2013
    Publication date: July 17, 2014
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20140182003
    Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: October 17, 2013
    Publication date: June 26, 2014
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20140150125
    Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: October 17, 2013
    Publication date: May 29, 2014
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20140150126
    Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: October 17, 2013
    Publication date: May 29, 2014
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20140134156
    Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: December 20, 2013
    Publication date: May 15, 2014
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20140120582
    Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: November 14, 2013
    Publication date: May 1, 2014
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20130318643
    Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: January 14, 2013
    Publication date: November 28, 2013
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20130251724
    Abstract: The present invention concerns antigen binding proteins and fragments thereof which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and which inhibit the binding of OSM to the gp130 receptor but does not directly interact with site II residues. The invention also concerns a method of humanising antibodies. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Application
    Filed: November 21, 2011
    Publication date: September 26, 2013
    Applicant: Glaxo Group Limited
    Inventors: Gary Peter Bembridge, Chun-Wa Chung, Maria Feeney, Susannah Karen Ford, Ian Kirby, Ruth McAdam
  • Patent number: 8541718
    Abstract: Disclosed is an apparatus for processing a hypodermic needle (2), comprising: means for softening the needle; and means (120) for providing a compressive force to the needle.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: September 24, 2013
    Assignee: Needlesmart Holdings Limited
    Inventors: Clifford Ian Kirby, Norman Trevor Douce
  • Publication number: 20130042331
    Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: March 9, 2012
    Publication date: February 14, 2013
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20120282254
    Abstract: Antigen binding proteins which bind to human IL-7 receptor (CD127) are provided. The antigen binding proteins are typically antibodies, and are useful in the treatment of diseases or disorders in humans, particularly autoimmune diseases such as multiple sclerosis.
    Type: Application
    Filed: January 26, 2011
    Publication date: November 8, 2012
    Inventors: Ian Kirby, Alexander H. Taylor, Thomas Matthew Webb, Yu Xue
  • Patent number: 8285997
    Abstract: A system for more secure, more efficient, more widely applicable backup, retention, and retrieval of data. An apparatus comprising improved means for de-duplication of data and securely storing data remotely with efficient retention and recovery. A method comprising disassembling data objects, efficiently de-duplicating, securely storing and retrieving backups in shared servers on a public network, and controlling retention.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: October 9, 2012
    Assignee: Barracuda Networks, Inc.
    Inventors: Lindsay Eugene Snider, Ian Kirby Berry
  • Publication number: 20120204278
    Abstract: The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: December 2, 2011
    Publication date: August 9, 2012
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20120167237
    Abstract: The invention discloses methods for the generation of chimaeric human-non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.
    Type: Application
    Filed: March 9, 2012
    Publication date: June 28, 2012
    Applicant: Kymab Limited
    Inventors: Allan Bradley, E-Chiang Lee, Qi Liang, Wei Wang, Anais Legent, Ian Kirby
  • Publication number: 20120100137
    Abstract: The present invention discloses humanised anti-IL-18 antibodies, methods of manufacture, and methods of treatment with said antibodies. Further disclosed are screening methods using for example surface plasmon resonance to identify antibodies with therapeutic potential.
    Type: Application
    Filed: December 9, 2011
    Publication date: April 26, 2012
    Inventors: Jonathan Henry Ellis, Volker Germaschewski, Paul Andrew Hamblin, Ian Kirby
  • Publication number: 20110278281
    Abstract: Disclosed is an apparatus for processing a hypodermic needle (2), comprising: means for softening the needle; and means (120) for providing a compressive force to the needle.
    Type: Application
    Filed: January 29, 2010
    Publication date: November 17, 2011
    Applicant: NEEDLESMART HOLDINGS LIMITED
    Inventors: Clifford Ian Kirby, Norman Trevor Douce
  • Publication number: 20110256132
    Abstract: Description of antigen binding proteins, such as antibodies, which bind to myostatin, polynucleotides encoding such antigen binding proteins, pharmaceutical compositions comprising said antigen binding proteins and methods of manufacture. Furthermore, description of the use of such antigen binding proteins in the treatment or prophylaxis of diseases associated with anyone or a combination of decreased muscle mass, muscle strength and muscle function.
    Type: Application
    Filed: December 18, 2009
    Publication date: October 20, 2011
    Inventors: Claire Ashman, Andrew Beaton, Jonathan Henry Ellis, Baijin Han, Ian Kirby, Frederick Kull, Alan Lewis, Kathryn Mason Lindley, Martin Anibal Orecchia, Ying Shen, Paul Wilson, Tian Shun Xun, Hong Zhang