Patents by Inventor Ian Lewis
Ian Lewis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12209144Abstract: The disclosure relates to inhibitors of PCSK9 useful in the treatment of lipid metabolism, and other diseases in which PCSK9 plays a role, having the Formula (I): or a pharmaceutically acceptable salt, hydrate, solvate, stereoisomer, or tautomer thereof, wherein R1, X1, X2, X3, X4, X5, X6, X7, X8, X9, X10, X11, X12, and X13 are described herein.Type: GrantFiled: November 26, 2019Date of Patent: January 28, 2025Assignee: Novartis AGInventors: Alec Nathanson Flyer, Andrei Alexandrovich Golosov, Philipp Grosche, Ian Lewis, Eugene Yuejin Liu, Andreas Marzinzik, Lauren Gilchrist Monovich, Johannes Ottl, Tajesh Jayprakash Patel, Patrick Crawford Reid, Mohindra Seepersaud
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Publication number: 20200281964Abstract: Provided herein are compositions, for example: oral rehydration compositions, beverages, food items, methods and uses, which utilise resistant starch to prevent or treat dehydration, including dehydration which is caused by diarrhoea. Beverages, food items and oral rehydration solutions including a resistant starch, which are suitable for aiding in the maintenance and restoration of hydration levels in individuals undertaking physical activities, including sports, are also disclosed.Type: ApplicationFiled: February 12, 2020Publication date: September 10, 2020Inventors: Balakrishnan Siddartha Ramakrishna, Graeme Paul Young, Ian Lewis Brown, Henry Joseph Binder
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Patent number: 10596187Abstract: Provided herein are compositions, for example: oral rehydration compositions, beverages, food items, methods and uses, which utilise resistant starch to prevent or treat dehydration, including dehydration which is caused by diarrhoea. Beverages, food items and oral rehydration solutions including a resistant starch, which are suitable for aiding in the maintenance and restoration of hydration levels in individuals undertaking physical activities, including sports, are also disclosed.Type: GrantFiled: November 7, 2014Date of Patent: March 24, 2020Assignees: Yale University, Flinders University of South Australia, Balakrishnan Siddartha RamakrishnaInventors: Balakrishnan Siddartha Ramakrishna, Graeme Paul Young, Ian Lewis Brown, Henry Joseph Binder
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Patent number: 9949979Abstract: The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.Type: GrantFiled: December 14, 2012Date of Patent: April 24, 2018Assignee: Novartis AGInventors: Nigel Graham Cooke, Paulo Antonio Fernandes Gomes Dos Santos, Pascal Furet, Christina Hebach, Klemens Hoegenauer, Gregory Hollingworth, Christoph Kalis, Ian Lewis, Alexander Baxter Smith, Nicolas Soldermann, Frederic Stauffer, Ross Strang, Frank Stowasser, Nicola Tuffilli, Anette Von Matt, Romain Wolf, Frederic Zecri
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Patent number: 9763952Abstract: The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein Y, V, W, U, Q, R1, R5, R7 and R30 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.Type: GrantFiled: December 21, 2015Date of Patent: September 19, 2017Assignee: NOVARTIS AGInventors: Giorgio Caravatti, Sylvie Chamoin, Pascal Furet, Klemens Hogenauer, Konstanze Hurth, Karen Kammertoens, Ian Lewis, Henrik Moebitz, Alexander Baxter Smith, Nicolas Soldermann, Romain Wolf, Frederic Zecri
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Patent number: 9539260Abstract: The invention relates to dihydro-benzo-oxazine and dihydro-pyrido-oxazine compounds of the formula (I) and/or pharmaceutically acceptable salts and/or solvates thereof, wherein Y, V, W, U, Q, R1, R5, R7 and R30 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.Type: GrantFiled: December 20, 2012Date of Patent: January 10, 2017Assignee: NOVARTIS AGInventors: Giorgio Caravatti, Sylvie Chamoin, Pascal Furet, Klemens Hogenauer, Konstanze Hurth, Karen Kammertoens, Ian Lewis, Henrik Moebitz, Alexander Baxter Smith, Nicolas Soldermann, Romain Wolf, Frederic Zecri
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Publication number: 20160286838Abstract: Provided herein are compositions, for example: oral rehydration compositions, beverages, food items, methods and uses, which utilise resistant starch to prevent or treat dehydration, including dehydration which is caused by diarrhoea. Beverages, food items and oral rehydration solutions including a resistant starch, which are suitable for aiding in the maintenance and restoration of hydration levels in individuals undertaking physical activities, including sports, are also disclosed.Type: ApplicationFiled: November 7, 2014Publication date: October 6, 2016Inventors: Balakrishnan Siddartha RAMAKRISHNA, Graeme Paul YOUNG, Ian Lewis BROWN, Henry Joseph BINDER
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Patent number: 9344543Abstract: A system is providing for augmenting multimedia playback on a mobile device. The system includes the mobile device and an auxiliary loudspeaker device. The mobile device includes a telecoil transmitter and is configured to, in a multimedia mode, provide a multimedia audio signal to the telecoil transmitter for transmission to the auxiliary loudspeaker device. The auxiliary loudspeaker device includes a telecoil to receive the transmitted multimedia audio signal and plays a low frequency portion of multimedia audio content at a loudspeaker of the auxiliary loudspeaker device.Type: GrantFiled: July 15, 2014Date of Patent: May 17, 2016Assignee: Wistron CorporationInventors: Ian Lewis, Michael Burke
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Publication number: 20160021229Abstract: A system is providing for augmenting multimedia playback on a mobile device. The system includes the mobile device and an auxiliary loudspeaker device. The mobile device includes a telecoil transmitter and is configured to, in a multimedia mode, provide a multimedia audio signal to the telecoil transmitter for transmission to the auxiliary loudspeaker device. The auxiliary loudspeaker device includes a telecoil to receive the transmitted multimedia audio signal and plays a low frequency portion of multimedia audio content at a loudspeaker of the auxiliary loudspeaker device.Type: ApplicationFiled: July 15, 2014Publication date: January 21, 2016Inventors: Ian Lewis, Michael Burke
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Publication number: 20150369688Abstract: A device, system and method for determining a seal quality of a sealed environment is provided herein. A seal detection device is utilized to determine a seal quality for an acoustic cavity of a microphone for a mobile device. The seal detection device determines an acoustic impedance at the end of a hollow longitudinal section by propagating a broadband audio signal from a source speaker through the hollow longitudinal section into the acoustic cavity. Located within the hollow longitudinal section is a microphone measurement portion configured to provide an output signal to measurement equipment in order to determine a transfer function between of the microphone measurement portion. Utilizing the transfer function, the seal quality can be determined for the acoustic cavity.Type: ApplicationFiled: June 19, 2014Publication date: December 24, 2015Inventor: Ian Lewis
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Publication number: 20150218223Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O—)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.Type: ApplicationFiled: April 8, 2015Publication date: August 6, 2015Applicant: Novartis AGInventors: Rainer Albert, Wilfried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meisenbach, Gisbert Weckbecker, Bernhard Wietfeld
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Patent number: 9035021Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O—)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.Type: GrantFiled: March 16, 2011Date of Patent: May 19, 2015Assignee: Novartis AGInventors: Rainer Albert, Wilfried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meisenbach, Gisbert Weckbecker, Bernhard Wietfeld
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Publication number: 20140249139Abstract: The invention relates to substituted quinazoline derivative of the formula (I), wherein A, X1, X2, X3, X4 and R5 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.Type: ApplicationFiled: October 19, 2012Publication date: September 4, 2014Applicant: NOVARTIS AGInventors: Pascal Furet, Christina Hebach, Klemens Hogenauer, Gregory Hollingworth, Ian Lewis, Alexander Baxter Smith, Nicolas Solvermann, Frederic Stauffer, Romain Wolf, Frederic Zecri
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Patent number: 8822637Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O-)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.Type: GrantFiled: March 16, 2011Date of Patent: September 2, 2014Assignee: Novartis AGInventors: Rainer Albert, Wilfried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meisenbach, Gisbert Weckbecker, Bernhard Wietfeld
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Patent number: 8619086Abstract: Three dimensional scenes may be managed between a central processing unit and a graphics processing unit using shared and unified graphics processing unit memory. A shared bus memory may be synchronized between the central processing unit and the graphics processing unit. The shared bus memory may be used for more often updated components and other memory may be used for less often updated components. In some embodiments, if the graphics processor and the central processor use a common processor instruction set architecture, data can be sent from the central processor to the graphics processor without serializing the data.Type: GrantFiled: April 30, 2009Date of Patent: December 31, 2013Assignee: Intel CorporationInventors: Antony Arciuolo, Ian Lewis, Kevin Myers
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Publication number: 20110172157Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O—)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.Type: ApplicationFiled: March 16, 2011Publication date: July 14, 2011Applicant: NOVARTIS AGInventors: Rainer Albert, Wilfried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meisenbach, Gisbert Weckbecker, Bernhard Wietfeld
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Publication number: 20110166320Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O—)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.Type: ApplicationFiled: March 16, 2011Publication date: July 7, 2011Applicant: NOVARTIS AGInventors: Rainer Albert, Wilfried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meisenbach, Gisbert Weckbecker, Bernhard Wietfeld
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Patent number: 7939625Abstract: The invention provides cyclo[{4-(NH2—C2H4—NH—CO—O—)Pro}-Phg-DTrp-Lys-Tyr(4-Benzyl)-Phe], optionally in protected form, or a pharmaceutically acceptable salt or complex thereof, which has interesting pharmaceutical properties.Type: GrantFiled: November 5, 2008Date of Patent: May 10, 2011Assignee: Novartis AGInventors: Rainer Albert, Wilfried Bauer, David Bodmer, Christian Bruns, Ivo Felner, Heribert Hellstern, Ian Lewis, Mark Meisenbach, Gisbert Weckbecker, Bernhard Wietfeld
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Publication number: 20110052538Abstract: This invention pertains to a method of promoting gastrointestinal health by ingesting a composition comprising one or more probiotic microorganisms, one or more carbohydrate sources, and one or more resistant protein products. Large intestinal health is benefited by one or more of the following: increased fecal weight, lower fecal pH, increased carbohydrate fermentation, and amelioration of protein fermentation.Type: ApplicationFiled: October 18, 2010Publication date: March 3, 2011Applicant: BRUNOB II B.V.Inventors: Ian Lewis Brown, Anne M. Birkett, Richard Le Leu, Graeme P. Young
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Publication number: 20100277488Abstract: A rasterizer may use only triangle position information. In this way, it is not necessary to rasterize objects that end up being culled in screen space.Type: ApplicationFiled: April 30, 2009Publication date: November 4, 2010Inventors: Kevin Myers, Antony Arciuolo, Ian Lewis