Patents by Inventor Ian M. Orme

Ian M. Orme has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for the treatment or prevention of tuberculosis
    Patent number: 10722567
    Abstract: Disclosed are yeast-based immunotherapeutic compositions and fusion proteins for the treatment and/or prevention of TB infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions and fusion proteins for the prophylactic and/or therapeutic treatment of TB and/or symptoms thereof.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: July 28, 2020
    Assignees: GlobeImmune, Inc., Colorado State University Research Foundation
    Inventors: Thomas H. King, Zhimin Guo, Ian M. Orme
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF TUBERCULOSIS
    Publication number: 20190151429
    Abstract: Disclosed are yeast-based immunotherapeutic compositions and fusion proteins for the treatment and/or prevention of TB infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions and fusion proteins for the prophylactic and/or therapeutic treatment of TB and/or symptoms thereof.
    Type: Application
    Filed: February 4, 2019
    Publication date: May 23, 2019
    Inventors: Thomas H. KING, Zhimin GUO, Ian M. ORME
  • Compositions and methods for the treatment or prevention of tuberculosis
    Patent number: 10226522
    Abstract: Disclosed are yeast-based immunotherapeutic compositions and fusion proteins for the treatment and/or prevention of TB infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions and fusion proteins for the prophylactic and/or therapeutic treatment of TB and/or symptoms thereof.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: March 12, 2019
    Assignees: GLOBEIMMUNE, INC., COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Thomas H. King, Zhimin Guo, Ian M. Orme
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF TUBERCULOSIS
    Publication number: 20160213767
    Abstract: Disclosed are yeast-based immunotherapeutic compositions and fusion proteins for the treatment and/or prevention of TB infection and symptoms thereof, as well as methods of using the yeast-based immunotherapeutic compositions and fusion proteins for the prophylactic and/or therapeutic treatment of TB and/or symptoms thereof.
    Type: Application
    Filed: August 29, 2014
    Publication date: July 28, 2016
    Inventors: Thomas H. KING, Zhimin GUO, Ian M. ORME
  • Mid-life vaccine and methods for boosting anti-mycobacterial immunity
    Patent number: 7288261
    Abstract: Vaccine compositions for boosting immunity to mycobacteria when administered in mid-life in a subject who has been vaccinated neonatally or in early childhood with BCG and in whom protective immunity has waned comprise one or more purified immunogenic proteins from Mycobacterium tuberculosis from a group of 30 proteins that stimulate T cell immunity and interferon-? secretion. A preferred protein is Ag85A, the secreted product (SEQ ID NO:31) of the Rv3084c gene. Also disclosed are methods for boosting immunity in such BCG-vaccinated subjects comprising administering an effective amount of the above vaccine composition.
    Type: Grant
    Filed: July 10, 2001
    Date of Patent: October 30, 2007
    Assignee: Colorado State University Research Foundation
    Inventors: Ian M. Orme, John T. Belisle
  • Mid-life vaccine and methods for boosting anti-mycobacterial immunity
    Publication number: 20040180056
    Abstract: Vaccine compositions for boosting immunity to mycobacteria when administered in mid-life in a subject who has been vaccinated neonatally or in early childhood with BCG and in whom protective immunity has waned comprise one or more purified immunogenic proteins from Mycobacterium tuberculosis from a group of 30 proteins that stimulate T cell immunity and interferon-&ggr; secretion. A preferred protein is Ag85A, the secreted product (SEQ ID NO:31) of the Rv3084c gene. Also disclosed are methods for boosting immunity in such BCG-vaccinated subjects comprising administering an effective amount of the above vaccine composition.
    Type: Application
    Filed: November 24, 2003
    Publication date: September 16, 2004
    Inventors: Ian M Orme, John T Belisle