Patents by Inventor Ian McCaffery

Ian McCaffery has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pancreatic cancer secreted targets and uses thereof
    Publication number: 20080219992
    Abstract: The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAST) and antibodies binds to PCAST. The present invention provides that PCAST is used as targets for screening agents that modulates the PCAST activities. Further the present invention provides methods for treating diseases associated with pancreas.
    Type: Application
    Filed: February 13, 2008
    Publication date: September 11, 2008
    Applicant: APPLERA CORPORATION
    Inventors: Kim Alving, Steve Ruben, Ian McCaffery, Bruno Domon
  • Selective capture and enrichment of proteins expressed on the cell surface
    Publication number: 20080076907
    Abstract: The present invention provides a method for enriching cell surface proteins by oxidizing glycosylated protein with periodate. The present invention further provides that the cell surface proteins are obtained from intact cells either from cell lines or from tissues. The present invention provides a method not only capable of obtaining increased quantities of the cell surface proteins, but also capable of obtaining a wide ranges of proteins that are not detectable by other means.
    Type: Application
    Filed: September 28, 2007
    Publication date: March 27, 2008
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Terence Ryan
  • Selective capture and enrichment of proteins expressed on the cell surface
    Patent number: 7348416
    Abstract: The present invention provides a method for enriching cell surface proteins by oxidizing glycosylated protein with periodate. The present invention further provides that the cell surface proteins are obtained from intact cells either from cell lines or from tissues. The present invention provides a method not only capable of obtaining increased quantities of the cell surface proteins, but also capable of obtaining a wide ranges of proteins that are not detectable by other means.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: March 25, 2008
    Assignee: Applera Corporation
    Inventors: Bruno Domon, Ian McCaffery, Terence Ryan
  • Method and compositions for the treating diseases targeting E-cadherin
    Publication number: 20070059757
    Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of E-cadherin in comparison to healthy cells. Also provided are antagonists or agonists of E-cadherin, and methods for screening agents that modulate the E-cadherin level or activity in vivo or in vitro.
    Type: Application
    Filed: November 13, 2006
    Publication date: March 15, 2007
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Selective capture and enrichment of proteins expressed on the cell surface
    Publication number: 20060154332
    Abstract: The present invention provides a method for enriching cell surface proteins by oxidizing glycosylated protein with periodate. The present invention further provides that the cell surface proteins are obtained from intact cells either from cell lines or from tissues. The present invention provides a method not only capable of obtaining increased quantities of the cell surface proteins, but also capable of obtaining a wide ranges of proteins that are not detectable by other means.
    Type: Application
    Filed: November 19, 2004
    Publication date: July 13, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Terence Ryan
  • Method and compositions for treating diseases targeting CD71
    Publication number: 20060039907
    Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of CD71 in comparison to healthy cells. Also provided are antagonists or agonists of CD71, and methods for screening agents that modulate the CD71 level or activity in vivo or in vitro.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 23, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Method and compositions for treating diseases targeting CD51
    Publication number: 20060035239
    Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of CD51 in comparison to healthy cells. Also provided are antagonists or agonists of CD51, and methods for screening agents that modulate the CD51 level or activity in vivo or in vitro.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 16, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Diagnosis of pancreatic cancer by using pancreatic targets
    Publication number: 20060029987
    Abstract: Methods and compositions for diagnosing, detecting a pancreatic disease associated with differential expression of PCATs (e.g., CD49b, CD51, CD71 and E-Cadherin) in comparison to healthy cells.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 9, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson
  • Method and compositions for treating diseases targeting E-cadherin
    Publication number: 20060029988
    Abstract: Methods and compositions for diagnosing, detecting and treating a pancreatic disease associated with differential expression of E-cadherin in comparison to healthy cells. Also provided are antagonists or agonists of E-cadherin, and methods for screening agents that modulate the E-cadherin level or activity in vivo or in vitro.
    Type: Application
    Filed: August 6, 2004
    Publication date: February 9, 2006
    Applicant: APPLERA CORPORATION
    Inventors: Bruno Domon, Ian McCaffery, Vaibhav Narayan, Scott Patterson