Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to automated methods for the preparation and purification of 18F-labelled tau imaging radiotracers. Also provided are interchangeable cassettes useful in the methods, and the use of automated synthesizers and cassettes in the methods.

Abstract: The present invention relates to the field of radiopharmaceuticals for in vivo imaging, in particular to automated methods for the preparation and purification of 18F-labelled tau imaging radiotracers. Also provided are interchangeable cassettes useful in the methods, and the use of automated synthesizers and cassettes in the methods.

Abstract: A polymeric particulate material suitable for use in an ink-jet receiver is prepared by generating an emulsion comprising a first phase having a first carrier fluid and a second phase having a second carrier fluid, said first and second carrier fluids being immiscible; carrying out a first treatment to at least one component of the first phase to form and/or maintain a skeletal structure of the treated at least one component of the first phase; carrying out a second treatment to the second phase to substantially remove the carrier fluid thereby generating a large capacity porous structure defined by the skeletal structure; and mechanically dividing (e.g. milling) the skeletal structure. A coating of the particles is capable of rapid uptake of large quantities of ink, especially when formed using a high internal phase water-in-oil emulsion.

Abstract: The present invention provides a planographic printing element suitable to receive and bond with a subsequently applied hydrophilic layer comprises a substrate layer, such as polyester film or paper, having coated thereon an adhesion layer, said adhesion layer comprising a polymer having a glass transition temperature of less than 15 C and containing functional groups such as hydroxyl, epoxy or glycidyl groups capable of reacting with the hydrophilic layer. The polymer may be a terpolymer of a hydroxyalkyl methacrylate, an alkyl acrylate and an aminoalkyl methacrylate. The polymer may be mixed with gelatin and the mixture applied to the substrate as a coating. The hydrophilic layer, which may comprise metal oxide particles, such as aluminium oxide and/or titanium dioxide particles in a sodium silicate binder, is subsequently applied as a coating to the adhesion layer.

Abstract: A coating fluid for forming a coating on a support for use in inkjet printing comprises a liquid medium having dispersed therein (a) an inorganic oxide selected from aluminium oxide and silica, (b) a binder polymer, and (c) a polymeric crosslinking agent containing functional groups for reaction with the inorganic oxide. The components (a), (b) and (c) are preferably dispersed in an aqueous liquid and the relative amounts of inorganic oxide to polymeric crosslinking agent are from 500:1 to 15:1 preferably 250:1 to 20:1, the relative amounts of inorganic oxide to binder polymer are from 50:1 to 2:1 preferably 20:1 to 4:1 and the relative amounts of binder polymer to polymeric crosslinking agent are from 40:1 to 2:1 preferably from 20:1 to 3:1 the amounts being by weight on a dry basis.