Patents by Inventor Ian Nicholas Houson

Ian Nicholas Houson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process
    Publication number: 20100029985
    Abstract: A process for the preparation of a compound of Formula (1) wherein Ar represents an optionally substituted hydrocarbyl or an optionally substituted heterocyclyl group comprising an aromatic moiety; and R1 and R2 each independently represent an optionally substituted hydrocarbyl or an optionally substituted heterocyclyl group; said process comprising: a) reducing a compound of Formula (2) to form a compound of Formula (3): b) activating the compound of Formula (3) to form a compound of Formula (4): wherein OX represents a leaving group; and c) coupling the compound of Formula (4) to a compound of Formula (5): to form a compound of Formula (1). A stereoselective reduction of ketones to alcohols is also disclosed.
    Type: Application
    Filed: December 14, 2005
    Publication date: February 4, 2010
    Applicant: AVECIA PHARMACEUTICALS LIMITED
    Inventors: George Robert Hodges, Juliette Martin, Noel Anthony Hammil, Ian Nicholas Houson
  • Processes for the preparation of heterocyclic hydroxyamines and intermediates and catalysts for use therein
    Patent number: 7462731
    Abstract: A process for the preparation of a compound of Formula (1): wherein: X is S, O or NR3, wherein R3 is H or an organic group; R is H or an organic group; R1 and R2 each independently are H, optionally substituted alkyl or optionally substituted aryl; G is a substituent; and n is 0 to 3: which comprises the steps: (a) reacting a compound of Formula (2) with a compound of Formula NHR1R2 to give a compound of Formula (3): wherein X, R, G and n are as defined above and R4 is optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted aryl, optionally substituted heteroaryl or a combination thereof; and (b) reducing the compound of Formula (3) to give a compound of Formula (1) is provided.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: December 9, 2008
    Assignee: NPIL Pharmaceuticals (UK) Limited
    Inventor: Ian Nicholas Houson
  • Preparation of mandelic acid derivatives
    Patent number: 7022876
    Abstract: A process is provided for the preparation of mandelic acid derivatives. The process comprises the steps of: (a) stereoselectively cyanating a compound of Formula (2) to yield the corresponding cyanohydrin; (b) hydrolyzing the product of step (a) to the corresponding compound of Formula (1). wherein X is a substituent.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: April 4, 2006
    Assignee: Avecia Ltd.
    Inventors: Andrew John Blacker, Ian Nicholas Houson
  • Process for the preparation of nitrile compounds
    Publication number: 20040254391
    Abstract: A process is provided for the preparation of a compound of Formula (1) 1
    Type: Application
    Filed: July 19, 2004
    Publication date: December 16, 2004
    Inventors: Andrew John Blacker, Ian Nicholas Houson, Jonathan William Wiffen
  • Preparation of mandelic acid derivatives
    Publication number: 20040068140
    Abstract: A process is provided for the preparation of mandelic acid derivatives.
    Type: Application
    Filed: August 5, 2003
    Publication date: April 8, 2004
    Inventors: Andrew John Blacker, Ian Nicholas Houson