Patents by Inventor Ian Paul Andrews

Ian Paul Andrews has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing tapinarof
    Patent number: 12275696
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Grant
    Filed: February 3, 2023
    Date of Patent: April 15, 2025
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Ian Paul Andrews, Nicholas Calandra, Tyler Andrew Davis, Ravinder Reddy Sudini
  • Ball valve with integral gear
    Patent number: 11708915
    Abstract: A ball valve includes a valve body. The valve body is driven to rotate through a drive train that includes a planetary gear set. A gear of the planetary gear set is integrally formed with the valve body. In an embodiment, a ring gear of the planetary gear set is integrally formed with the valve body.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: July 25, 2023
    Assignee: Eaton Intelligent Power Limited
    Inventors: Ian Paul Andrews, Daniel Bray
  • PROCESS FOR PREPARING TAPINAROF
    Publication number: 20230174445
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Application
    Filed: February 3, 2023
    Publication date: June 8, 2023
    Applicant: Dermavant Sciences GmbH
    Inventors: Ian Paul ANDREWS, Nicholas CALANDRA, Tyler Andrew DAVIS, Ravinder Reddy SUDINI
  • Process for preparing tapinarof
    Patent number: 11597692
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Grant
    Filed: February 12, 2021
    Date of Patent: March 7, 2023
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Ian Paul Andrews, Nicholas Calandra, Tyler Andrew Davis, Ravinder Reddy Sudini
  • BALL VALVE WITH INTEGRAL GEAR
    Publication number: 20210190232
    Abstract: A ball valve includes a valve body. The valve body is driven to rotate through a drive train that includes a planetary gear set. A gear of the planetary gear set is integrally formed with the valve body. In an embodiment, a ring gear of the planetary gear set is integrally formed with the valve body.
    Type: Application
    Filed: December 22, 2020
    Publication date: June 24, 2021
    Inventors: Ian Paul Andrews, Daniel Bray
  • PROCESS FOR PREPARING TAPINAROF
    Publication number: 20210163388
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Application
    Filed: February 12, 2021
    Publication date: June 3, 2021
    Inventors: Ian Paul ANDREWS, Nicholas CALANDRA, Tyler Andrew DAVIS, Ravinder Reddy SUDINI
  • Process for preparing tapinarof
    Patent number: 10961175
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: March 30, 2021
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Ian Paul Andrews, Nicholas Calandra, Tyler Andrew Davis, Ravinder Reddy Sudini
  • PROCESS FOR PREPARING TAPINAROF
    Publication number: 20210024442
    Abstract: The present invention provides processes for the preparation of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3,5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3,5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Application
    Filed: April 15, 2020
    Publication date: January 28, 2021
    Inventors: Ian Paul ANDREWS, Nicholas CALANDRA, Tyler Andrew DAVIS, Ravinder Reddy SUDINI
  • Process for preparing tapinarof
    Patent number: 10647649
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: May 12, 2020
    Assignee: DERMAVANT SCIENCES GMBH
    Inventors: Ian Paul Andrews, Nicholas Calandra, Tyler Andrew Davis, Ravinder Reddy Sudini
  • PROCESS FOR PREPARING TAPINAROF
    Publication number: 20190144367
    Abstract: The present invention provides processes for the preparation of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and novel intermediates used therein. In some embodiments the 3, 5-Dihydroxy-4-isopropyl-trans-stilbene is prepared from (E)-2-chloro-2-isopropyl-5-styrylcyclohexane-1,3-dione. Also disclosed are crystal forms of 3, 5-Dihydroxy-4-isopropyl-trans-stilbene or a salt or solvate thereof and pharmaceutical compositions comprising same.
    Type: Application
    Filed: November 13, 2018
    Publication date: May 16, 2019
    Inventors: Ian Paul ANDREWS, Nicholas CALANDRA, Tyler Andrew DAVIS, Ravinder Reddy SUDINI
  • Gas sensing device
    Patent number: 8318525
    Abstract: A device for sensing a gas comprises a plastics housing (106, 107) moulded in situ around at least one portion of a conducting lead frame (100), the housing defining an enclosure (113) and being provided with means for enabling gas flow into the enclosure. A gas sensitive element (114) within the enclosure (113) is mounted to the conducting lead frame (100). The conducting lead frame (100) comprises connection leads which are accessible through, and at least partially encapsulated by, the wall of the housing.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: November 27, 2012
    Assignee: City Technology Limited
    Inventors: David Frank Davies, Ian Paul Andrews, Anthony Richard Cowburn, Stuart Christopher Cutler
  • Environmental contaminant sampling and analysis
    Patent number: 7819028
    Abstract: A sampling and analysis device comprises a housing, a sampling region and an analysis region being defined within the housing. The housing has at least one aperture to allow fluid ingress to and egress from the sampling region. A filter is disposed within the housing, and is movable inside the housing between a sampling position, located in the sampling region, and an analysis position, located in the analysis region.
    Type: Grant
    Filed: September 22, 2005
    Date of Patent: October 26, 2010
    Assignee: Life Safety Distribution AG
    Inventors: Ian McIntyre Christie, Anthony Charles Downer, Ian Paul Andrews, Anthony Cooke
  • Environmental Contaminant Sampling and Analysis
    Publication number: 20080078256
    Abstract: A sampling and analysis device comprises a housing, a sampling region and an analysis region being defined within the housing. The housing has at least one aperture to allow fluid ingress to and egress from the sampling region. A filter is disposed within the housing, and is movable inside the housing between a sampling position, located in the sampling region, and an analysis position, located in the analysis region.
    Type: Application
    Filed: September 22, 2005
    Publication date: April 3, 2008
    Inventors: Ian McIntyre Christie, Anthony Charles Downer, Ian Paul Andrews, Anthony Cooke
  • Gas detector
    Patent number: D494879
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: August 24, 2004
    Assignee: City Technology Limited
    Inventor: Ian Paul Andrews