Patents by Inventor Ian R. Harris

Ian R. Harris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 11000554
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: May 11, 2021
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian R. Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
    Patent number: 10500234
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: December 10, 2019
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • POSTPARTUM CELLS DERIVED FROM PLACENTAL TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20190192577
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Application
    Filed: March 4, 2019
    Publication date: June 27, 2019
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian R. Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • METHOD OF INHIBITING ANGIOGENESIS
    Publication number: 20190134100
    Abstract: Methods and compositions for treating ophthalmic disease and reducing retinal neovascularization using progenitor cells, such as postpartum-derived cells, and conditioned media produced from the cells, are disclosed.
    Type: Application
    Filed: November 1, 2018
    Publication date: May 9, 2019
    Applicant: Janssen Biotech, Inc.
    Inventors: Jing Cao, Ian R. Harris
  • METHOD OF MODULATING MÜLLER GLIA CELLS
    Publication number: 20180344777
    Abstract: Methods and compositions for treating ophthalmic disease, in particular retinal degeneration, including modulating Müller glia, restoring retinal synaptic connectivity and forming ?2?1-containing synapses, using postpartum-derived cells are disclosed.
    Type: Application
    Filed: May 24, 2018
    Publication date: December 6, 2018
    Applicant: Janssen Biotech, Inc.
    Inventors: Ian R. Harris, Nadine S. Dejneka
  • METHODS OF OBTAINING CELLS FROM HUMAN POSTPARTUM UMBILICAL CORD ARTERIAL TISSUE
    Publication number: 20180346874
    Abstract: The invention provides for methods of obtaining cells from mammalian, preferably human, postpartum umbilical cord arterial tissue and use of these cells to treat ocular degenerative conditions. In particular, methods of the invention result in the isolation of a homogenous population of human postpartum umbilical cord arterial tissue-derived cells. In certain embodiments, the cells: express CD13, CD90, NG2, and HLA-ABC; do not express one or more of CD31, CD34, CD45, CD117, FSP1, and E-cadherin. In other embodiments, the cells secrete one or more of thrombospondin-1, BDNF and sVEGFR1.
    Type: Application
    Filed: May 24, 2018
    Publication date: December 6, 2018
    Applicant: Janssen Biotech, Inc.
    Inventors: Ian R. Harris, Nadine S. Dejneka
  • TREATMENT OF RETINAL DEGENERATION USING PROGENITOR CELLS
    Publication number: 20180327713
    Abstract: Methods and compositions for treating and reducing retinal degeneration using progenitor cells and conditioned media from progenitor cells, such as postpartum-derived cells are disclosed. Trophic factors and other agents secreted by the progenitor cells that protect retinal cells and inhibit apoptosis of retinal cells such as photoreceptor cells are also disclosed.
    Type: Application
    Filed: July 19, 2018
    Publication date: November 15, 2018
    Applicant: JANSSEN BIOTECH, INC.
    Inventors: IAN R. HARRIS, JING CAO, NADINE DEJNEKA
  • TREATMENT OF RETINAL VASCULAR DISEASE USING PROGENITOR CELLS
    Publication number: 20180015129
    Abstract: Methods and compositions for treating ophthalmic disease, reducing retinal neovascularization and retinal vascular leakage using progenitor cells, such as postpartum-derived cells, and conditioned media from the cells, are disclosed.
    Type: Application
    Filed: June 28, 2017
    Publication date: January 18, 2018
    Applicant: Janssen Biotech, Inc.
    Inventors: Ian R. Harris, Nadine Dejneka
  • POSTPARTUM CELLS DERIVED FROM UMBILICAL CORD TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20170326183
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 16, 2017
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
    Patent number: 9717763
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: August 1, 2017
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • TREATMENT OF RETINAL DEGENERATION USING PROGENITOR CELLS
    Publication number: 20170157179
    Abstract: Methods and compositions for treating and reducing retinal degeneration using progenitor cells and conditioned media from progenitor cells, such as postpartum-derived cells are disclosed. Genetic factors and receptors expressed by the progenitor cells that aid in protection of retinal cells and inhibition of apoptosis of retinal cells such as photoreceptor cells are also disclosed.
    Type: Application
    Filed: December 1, 2016
    Publication date: June 8, 2017
    Applicant: Janssen Biotech, Inc.
    Inventors: Ian R. Harris, Jing Cao, Nadine Dejneka
  • TREATMENT OF RETINAL DEGENERATION USING PROGENITOR CELLS
    Publication number: 20170080033
    Abstract: Methods and compositions for treating and reducing retinal degeneration using progenitor cells and conditioned media from progenitor cells, such as postpartum-derived cells are disclosed. Trophic factors and other agents secreted by the progenitor cells that protect retinal cells and inhibit apoptosis of retinal cells such as photoreceptor cells are also disclosed.
    Type: Application
    Filed: December 1, 2016
    Publication date: March 23, 2017
    Applicant: Janssen Biotech, Inc.
    Inventors: Ian R. Harris, Jing Cao, Nadine Dejneka
  • Regeneration and repair of neural tissue using postpartum-derived cells
    Patent number: 9572840
    Abstract: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: February 21, 2017
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Darin J. Messina, Alexander M. Harmon, Ian R. Harris, Anthony J. Kihm, Sanjay Mistry, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • CARDIAC TISSUE-DERIVED CELLS
    Publication number: 20160346331
    Abstract: The present invention is directed to methods and compositions for repairing damaged myocardium using human cardiac tissue-derived cells. In particular, the present invention provides methods and compositions for repairing damaged myocardium using expanded human cardiac tissue-derived cells that do not express telomerase.
    Type: Application
    Filed: August 17, 2016
    Publication date: December 1, 2016
    Applicant: Janssen Biotech, Inc.
    Inventors: Xiaozhen Wang, Ian R. Harris, Jeffrey S. Kennedy, Jing Yang, Susan Munga
  • Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
    Patent number: 9498501
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: November 22, 2016
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Treatment of Retinal Degeneration Using Progenitor Cells
    Publication number: 20160166619
    Abstract: Methods and compositions for treating and reducing retinal degeneration using progenitor cells and conditioned media from progenitor cells, such as postpartum-derived cells are disclosed. Trophic factors and other agents secreted by the progenitor cells that protect retinal cells and inhibit apoptosis of retinal cells such as photoreceptor cells are also disclosed.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 16, 2016
    Applicant: Janssen Biotech, Inc.
    Inventors: Ian R. Harris, Jing Cao, Nadine Dejneka
  • Treatment of Ocular Conditions Using Progenitor Cells
    Publication number: 20160158293
    Abstract: Methods and compositions for treating ophthalmic disease, promoting development of functional neuronal synapses and improving neuronal outgrowth using progenitor cells, such as postpartum-derived cells, and conditioned media from the cells, are disclosed. Trophic factors and other agents secreted by the cells that promote synapse formation and neuronal growth are also disclosed.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 9, 2016
    Applicant: JANSSEN BIOTECH, INC.
    Inventors: IAN R. HARRIS, NADINE DEJNEKA
  • Postpartum cells derived from umbilical tissue and methods of making and using the same
    Patent number: 8815587
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Grant
    Filed: November 15, 2010
    Date of Patent: August 26, 2014
    Assignee: DePuy Synthes Products, LLC
    Inventors: Ian R. Harris, Darin J. Messina, Anthony J. Kihm, Agnieszka Seyda, David C. Colter
  • REGENERATION AND REPAIR OF NEURAL TISSUE USING POSTPARTUM-DERIVED CELLS
    Publication number: 20140154226
    Abstract: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
    Type: Application
    Filed: January 10, 2014
    Publication date: June 5, 2014
    Applicant: DePuy Synthes Products, LLC
    Inventors: Darin J. Messina, Alexander M. Harmon, Ian R. Harris, Anthony J. Kihm, Sanjay Mistry, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Regeneration and repair of neural tissue using postpartum-derived cells
    Patent number: 8658152
    Abstract: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
    Type: Grant
    Filed: September 6, 2012
    Date of Patent: February 25, 2014
    Assignee: DePuy Synthes Products, LLC
    Inventors: Darin J. Messina, Alexander M. Harmon, Ian R. Harris, Anthony J. Kihm, Sanjay Mistry, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska