Patents by Inventor Ian S. Dunn

Ian S. Dunn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140335050
    Abstract: The invention features methods, compositions, and kits for the administration of an HSP90 inhibitor, OBAA, flunarizine, aphidicolin, damnacanthal, dantrolene, or an analog thereof, alone, or in combination with, e.g., a TAA, an antigen-binding scaffold (e.g., an antibody, a soluble T cell receptor, or a chimeric receptor) specific for a TAA, a cell (e.g., a white blood cell that targets a cancer cell), and/or an IFN-? receptor agonist or an IFN-? receptor agonist, for the treatment of cancer.
    Type: Application
    Filed: May 25, 2012
    Publication date: November 13, 2014
    Applicants: The General Hospital Corporation, CytoCure LLC
    Inventors: Timothy J. Haggerty, James T. Kurnick, Ian S. Dunn
  • Publication number: 20120195855
    Abstract: The invention provides methods of modulating tumor antigen associated (TAA) expression, and methods of modulating TAA expression in order to treat a tumor. More particularly, the invention provides methods of increasing an immune response against a tumor cell. Methods include administering to a subject with a tumor an amount of IFN-? receptor agonist and tumor associated antigen (TAA) sufficient to increase an immune response against the tumor cell.
    Type: Application
    Filed: October 19, 2011
    Publication date: August 2, 2012
    Applicant: CytoCure LLC
    Inventors: Paul J. Durda, James T. Kurnick, Ian S. Dunn
  • Patent number: 8071321
    Abstract: The invention provides methods of modulating tumor antigen associated (TAA) expression, and methods of modulating TAA expression in order to treat a tumor. More particularly, the invention provides methods of increasing an immune response against a tumor cell. Methods include administering to a subject with a tumor an amount of IFN-? receptor agonist and tumor associated antigen (TAA) sufficient to increase an immune response against the tumor cell.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: December 6, 2011
    Assignee: CytoCure LLC
    Inventors: Paul Durda, James T. Kurnick, Ian S. Dunn
  • Publication number: 20090215029
    Abstract: The invention provides methods for isolating or purifying a biomolecule directly or indirectly bound to a region of interest of a nucleic acid in a cell, and methods for isolating or purifying a biomolecule that directly or indirectly binds to a region of interest of a nucleic acid in a cell. The invention further provides substantially cell free, isolated and purified biomolecule(s) that are fixed or cross-linked to a region of interest of a nucleic acid, which optionally reflects the interaction of the biomolecule(s) with the nucleic acid in the cell (e.g., in native chromatin) when fixed or cross-linked to the region of interest. Substantially cell free, isolated and purified biomolecules that are fixed or cross-linked to a region of interest of a nucleic acid can remain fixed or cross-linked to the region of interest of the nucleic acid when heated or treated with denaturing compounds or agents.
    Type: Application
    Filed: January 16, 2008
    Publication date: August 27, 2009
    Applicant: CytoCure, Inc.
    Inventors: Matthew M. Lawler, Timothy J. Haggerty, Ian S. Dunn
  • Publication number: 20040253235
    Abstract: The invention provides methods of modulating tumor antigen associated (TAA) expression, and methods of modulating TAA expression in order to treat a tumor. More particularly, the invention provides methods of increasing an immune response against a tumor cell. Methods include administering to a subject with a tumor an amount of IFN-&bgr; receptor agonist and tumor associated antigen (TAA) sufficient to increase an immune response against the tumor cell.
    Type: Application
    Filed: August 29, 2003
    Publication date: December 16, 2004
    Inventors: Paul Durda, James T. Kurnick, Ian S. Dunn