Patents by Inventor Ian T. Harrison
Ian T. Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 4207241Abstract: 2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, antipyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.Type: GrantFiled: March 27, 1978Date of Patent: June 10, 1980Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 4174399Abstract: 6-(N-vinylureido)penicillanic acids and salts thereof; and processes for preparing such compounds are disclosed. The compounds are useful as inhibitors of lactic acidosis in ruminants.Type: GrantFiled: July 10, 1978Date of Patent: November 13, 1979Assignee: Syntex (USA) Inc.Inventors: Arthur F. Kluge, Ian T. Harrison
-
Patent number: 4097674Abstract: 2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.Type: GrantFiled: September 27, 1976Date of Patent: June 27, 1978Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 4051233Abstract: 2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.Type: GrantFiled: May 10, 1976Date of Patent: September 27, 1977Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 4048330Abstract: Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid derivatives substituted at the 2-position of the acetic acid moiety with methyl, ethyl, difluoromethyl, or methylene, and the salts and esters thereof, having anti-inflammatory, analgesic and anti-pyretic activities, and methods for the use thereof in the treatment of inflammation, pain and pyrexia.Type: GrantFiled: August 18, 1975Date of Patent: September 13, 1977Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Naphthyl acetaldehyde derivatives; methods of use thereof; and processes for the preparation thereof
Patent number: 4045485Abstract: 2-(2'-Naphthyl) acetaldehyde derivatives optionally substituted at the 2 position and/or positions C-1',4',5',7' or 8'; and/or position C-6' or positions C-5' and 7' exhibit anti-inflammatory, analgesic, antipyretic and anti-pruritic activity.Type: GrantFiled: November 5, 1976Date of Patent: August 30, 1977Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison -
Patent number: 4009197Abstract: 2-(6'-Substituted-2'-naphthyl)acetic acid derivatives substituted at the 2-position of the acetic acid moiety with methyl, methylene or halomethylene and the salts and esters thereof have anti-inflammatory, analgesic and anti-pyretic activities.Type: GrantFiled: May 1, 1975Date of Patent: February 22, 1977Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 4001301Abstract: 2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, antipyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.Type: GrantFiled: March 17, 1975Date of Patent: January 4, 1977Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 3998966Abstract: 2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.Type: GrantFiled: March 17, 1975Date of Patent: December 21, 1976Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 3989720Abstract: Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 5-Methylsulfinyl-7-isopropoxyxanthone-2-carboxylic acid and 5,7-di(methylsulfinyl)xanthone-2-carboxylic acid are illustrated as representative compounds.Type: GrantFiled: December 4, 1975Date of Patent: November 2, 1976Assignee: Syntex (U.S.A.) Inc.Inventors: Jurg R. Pfister, Ian T. Harrison, John H. Fried
-
Patent number: 3989721Abstract: Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 5-Methylsulfinyl-7-isopropoxyxanthone-2-carboxylic acid and 5,7-di(methylsulfinyl)xanthone-2-carboxylic acid are illustrated as representative compounds.Type: GrantFiled: December 4, 1975Date of Patent: November 2, 1976Assignee: Syntex (U.S.A.) Inc.Inventors: Jurg R. Pfister, Ian T. Harrison, John H. Fried
-
Patent number: 3988352Abstract: Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 5-Methylsulfinyl-7-isopropoxyxanthone-2-carboxylic acid and 5,7-di(methylsulfinyl)xanthone-2-carboxylic acid are illustrated as representative compounds.Type: GrantFiled: December 4, 1975Date of Patent: October 26, 1976Assignee: Syntex (U.S.A.) Inc.Inventors: Jurg R. Pfister, Ian T. Harrison, John H. Fried
-
Patent number: 3980699Abstract: 2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.Type: GrantFiled: August 5, 1974Date of Patent: September 14, 1976Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 3979414Abstract: Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 5-Isopropyl-7-acetylxanthone-2-carboxylic acid is illustrated as a representative compound.Type: GrantFiled: December 4, 1975Date of Patent: September 7, 1976Assignee: Syntex (U.S.A.) Inc.Inventors: Jurg R. Pfister, Ian T. Harrison, John H. Fried
-
Patent number: 3978116Abstract: 2-Naphthyl acetic acid derivatives and the corresponding amides, esters, hydroxamic acids and addition salts thereof, optionally substituted at the .alpha.-position on the acetic acid moiety and/or at position 6 and/or at positions 1, 4, 7 or 8 on the naphthyl ring and optionally saturated at positions 3 and 4, are anti-inflammatory, analgesic, anti-pyretic and anti-pruritic agents. A pharmaceutical method of effecting treatment of inflammation, pain, pyrexia and pruritus by the administration of naphthyl acetic acid derivatives. A pharmaceutical composition for use in the treatment of the above maladies comprising a naphthyl acetic acid derivative.Type: GrantFiled: March 17, 1975Date of Patent: August 31, 1976Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 3965115Abstract: Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 5-Methyl-sulfinyl-7-isopropoxyxanthone-2-carboxylic acid and 5,7-di(methylsulfinyl)xanthone-2-carboxylic acid are illustrated as representative compounds.Type: GrantFiled: March 13, 1975Date of Patent: June 22, 1976Assignee: Syntex (U.S.A.) Inc.Inventors: Jurg R. Pfister, Ian T. Harrison, John H. Fried
-
Patent number: 3963752Abstract: Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 5-Methylsulfinyl-7-isopropoxyxanthone-2-carboxylic acid and 5,7-di(methylsulfinyl)xanthone-2-carboxylic acid are illustrated as representative compounds.Type: GrantFiled: March 13, 1975Date of Patent: June 15, 1976Assignee: Syntex (U.S.A.) Inc.Inventors: Jurg R. Pfister, Ian T. Harrison, John H. Fried
-
Patent number: 3963753Abstract: Compositions containing and methods employing, as the essential ingredient, novel disubstituted xanthone carboxylic acid compounds which are useful in the treatment of allergic conditions. Methods for preparing these compounds and compositions and intermediates therein are also disclosed. 5-Methyl-sulfinyl-7-isopropoxyxanthone-2-carboxylic acid and 5,7-di(methylsulfinyl)xanthone-2-carboxylic acid are illustrated as representative compounds.Type: GrantFiled: March 13, 1975Date of Patent: June 15, 1976Assignee: Syntex (U.S.A.) Inc.Inventors: Jurg R. Pfister, Ian T. Harrison, John H. Fried
-
Patent number: 3960936Abstract: 2-(2'-Naphthyl) acetaldehyde derivatives optionally substituted at the 2 position and/or positions C-1',4',5',7' or 8'; and/or position C-6' or positions C-5' and 7' exhibit anti-inflammatory, analgesic, antipyretic and anti-pruritic activity.Type: GrantFiled: April 25, 1974Date of Patent: June 1, 1976Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison
-
Patent number: 3958012Abstract: The d 2-(6-substituted-2-naphthyl)propanals of this invention are prepared by oxidizing the corresponding 2-(6-substituted-2-naphthyl)-1-propanols or by reducing d 2-(6-substituted-2-naphthyl)propionic acids, the 6-substituent being a methyl, ethyl, isopropyl, cyclopropyl, trifluoromethyl, vinyl, ethynyl, fluoro, chloro, methoxy, methoxymethyloxy, difluoromethoxy, methylthio, methoxymethylthio or difluoromethylthio group. The products have anti-inflammatory, analgesic and antipyretic activities.Type: GrantFiled: March 27, 1975Date of Patent: May 18, 1976Assignee: Syntex CorporationInventors: John H. Fried, Ian T. Harrison