Patents by Inventor Ian Windsor

Ian Windsor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200405829
    Abstract: Disclosed herein are circular zymogens of RNase 1 that have a proteolytic cleavage site and are activated by a specific protease. These circular zymogens are useful for treatment of disorders that are characterized by a specific protease (e.g., HIV-1 protease).
    Type: Application
    Filed: June 26, 2020
    Publication date: December 31, 2020
    Applicants: Massachusetts Institute of Technology, Wisconsin Alumni Research Foundation
    Inventors: Ronald Raines, Ian Windsor
  • Publication number: 20170327517
    Abstract: Protease inhibitors, particularly aspartyl protease inhibitors, and more particularly HIV protease inhibitors which are boronated to enhance activity or to enhance entry into cells. Compounds, prodrugs and salts thereof of this invention contain phenylboronate groups, in particular p-B(OH)2-phenyl groups, benzoxaborole groups or borono-pyridyl groups or analogous groups in which the boronate group is protected.
    Type: Application
    Filed: July 28, 2017
    Publication date: November 16, 2017
    Inventors: Ronald T. RAINES, Ian WINDSOR, Michael PALTE, John LUKESH
  • Patent number: 9738664
    Abstract: Protease inhibitors, particularly aspartyl protease inhibitors, and more particularly HIV protease inhibitors which are boronated to enhance activity or to enhance entry into cells. Compounds, prodrugs and salts thereof of this invention contain phenylboronate groups, in particular p -B(OH)2-phenyl groups, benzoxaborole groups or borono-pyridyl groups or analogous groups in which the boronate group is protected. Methods for treating AIDS and ARC as well as providing a method for treating or preventing HIV infection.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: August 22, 2017
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Ronald T. Raines, Ian Windsor, Michael Palte, John Lukesh
  • Publication number: 20160122366
    Abstract: Protease inhibitors, particularly aspartyl protease inhibitors, and more particularly HIV protease inhibitors which are boronated to enhance activity or to enhance entry into cells. Compounds, prodrugs and salts thereof of this invention contain phenylboronate groups, in particular p-B(OH)2-phenyl groups, benzoxaborole groups or borono-pyridyl groups or analogous groups in which the boronate group is protected.
    Type: Application
    Filed: October 29, 2015
    Publication date: May 5, 2016
    Inventors: Ronald T. Raines, Ian Windsor, Michael Palte, John Lukesh