Patents by Inventor Ib Groth Clausen
Ib Groth Clausen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100267584Abstract: The present invention relates to methods for monitoring differential expression of a plurality of genes in a first Bacillus cell relative to expression of the same genes in one or more second Bacillus cells using microarrays containing Bacillus genomic sequenced tags. The present invention also relates to computer readable media and computer-based systems. The present invention further relates to substrates containing an array of Bacillus licheniformis or Bacillus clausii GSTs.Type: ApplicationFiled: April 1, 2010Publication date: October 21, 2010Applicants: Novozymes A/S, Novozymes, Inc.Inventors: Alexandre Bolotine, Alexei Sorokine, Alla Lapidus, Randy M. Berka, Ib Groth Clausen
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Publication number: 20100256037Abstract: The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.Type: ApplicationFiled: June 18, 2010Publication date: October 7, 2010Applicant: Novozymes A/SInventors: Lene Lange, Wenping Wu, Dominique Aubert, Sara Landvik, Kirk Matthew Schnorr, Ib Groth Clausen
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Patent number: 7785853Abstract: The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.Type: GrantFiled: June 26, 2002Date of Patent: August 31, 2010Assignee: Novozymes A/SInventors: Lene Lange, Wenping Wu, Dominique Aubert, Sara Landvik, Kirk Matthew Schnorr, Ib Groth Clausen
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Patent number: 7691574Abstract: The present invention relates to methods for monitoring differential expression of a plurality of genes in a first Bacillus cell relative to expression of the same genes in one or more second Bacillus cells using microarrays containing Bacillus genomic sequenced tags. The present invention also relates to computer readable media and computer-based systems. The present invention further relates to substrates containing an array of Bacillus licheniformis or Bacillus clausii GSTs.Type: GrantFiled: August 12, 2005Date of Patent: April 6, 2010Assignees: Novozymes, Inc., Novozymes A/SInventors: Randy M. Berka, Ib Groth Clausen, Alexandre Bolotine, Alexei Sorokine, Alla Lapidus
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Publication number: 20090203074Abstract: A Bacillus licheniformis mutant host cell derived from a parent B. licheniformis host cell, which mutant host cell is mutated in one or more gene(s) encoding one or more secreted polypeptide(s) which is at least 80% identical to one or more of the polypeptides shown in SEQ ID NO's: 2 to 248, wherein the mutant host cell secretes at least 5% less of the one or more secreted polypeptide(s) than the parent host cell, when they are cultivated under comparable conditions.Type: ApplicationFiled: April 2, 2009Publication date: August 13, 2009Applicant: Novozymes A/SInventors: Jens Tonne Andersen, Steen Troels Jorgensen, Michael Dolbjerg Rasmussen, Peter Bjarke Olsen, Ib Groth Clausen
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Publication number: 20090176290Abstract: A Bacillus licheniformis mutant host cell derived from a parent B. licheniformis host cell, which mutant host cell is mutated in one or more gene(s) encoding one or more secreted polypeptide(s) which is at least 80% identical to one or more of the polypeptides shown in SEQ ID NO's: 2 to 248, wherein the mutant host cell secretes at least 5% less of the one or more secreted polypeptide(s) than the parent host cell, when they are cultivated under comparable conditions.Type: ApplicationFiled: March 5, 2009Publication date: July 9, 2009Applicant: Novozymes A/SInventors: Jens Tonne Andersen, Steen Troels Jorgensen, Michael Dolbjerg Rasmussen, Peter Bjarke Olsen, Ib Groth Clausen
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Patent number: 7521204Abstract: A Bacillus licheniformis mutant host cell derived from a parent B. licheniformis host cell, which mutant host cell is mutated in one or more gene(s) encoding one or more secreted polypeptide(s) which is at least 80% identical to one or more of the polypeptides shown in SEQ ID NO's: 2 to 248, wherein the mutant host cell secretes at least 5% less of the one or more secreted polypeptide(s) than the parent host cell, when they are cultivated under comparable conditions.Type: GrantFiled: March 25, 2003Date of Patent: April 21, 2009Assignee: Novozymes A/SInventors: Jens Tonne Andersen, Steen Troels Jorgensen, Michael Dolbjerg Rasmussen, Peter Bjarke Olsen, Ib Groth Clausen
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Patent number: 7186513Abstract: The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containing filamentous fungal expressed sequenced tags. The present invention also relates to filamentous fungal expressed sequenced tags and to computer readable media and substrates containing such expressed sequenced tags for monitoring expression of a plurality of genes in filamentous fungal cells.Type: GrantFiled: August 29, 2003Date of Patent: March 6, 2007Assignee: Novozymes, Inc.Inventors: Randy M. Berka, Michael W. Rey, Jeffrey R. Shuster, Sakari Kauppinen, Ib Groth Clausen, Peter Bjarke Olsen
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Patent number: 7018794Abstract: The present invention relates to methods for monitoring differential expression of a plurality of genes in a first Bacillus cell relative to expression of the same genes in one or more second Bacillus cells using microarrays containing Bacillus genomic sequenced tags. The present invention also relates to computer readable media and computer-based systems. The present invention further relates to substrates containing an array of Bacillus licheniformis or Bacillus clausii GSTs.Type: GrantFiled: October 5, 2001Date of Patent: March 28, 2006Assignee: Novozymes, Inc.Inventors: Randy M. Berka, Ib Groth Clausen, Alexandre Bolotine, Alexei Sorokine, Alla Lapidus
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Patent number: 6902887Abstract: The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containing filamentous fungal expressed sequenced tags. The present invention also relates to filamentous fungal expressed sequenced tags and to computer readable media and substrates containing such expressed sequenced tags for monitoring expression of a plurality of genes in filamentous fungal cells.Type: GrantFiled: March 22, 2000Date of Patent: June 7, 2005Assignees: Novozymes Biotech, Inc., Novozymes A/SInventors: Randy M. Berka, Michael W. Rey, Jeffrey R. Shuster, Sakari Kauppinen, Ib Groth Clausen, Peter Bjarke Olsen
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Publication number: 20040229367Abstract: The present invention relates to methods for monitoring differential expression of a plurality of genes in a first filamentous fungal cell relative to expression of the same genes in one or more second filamentous fungal cells using microarrays containing filamentous fungal expressed sequenced tags. The present invention also relates to filamentous fungal expressed sequenced tags and to computer readable media and substrates containing such expressed sequenced tags for monitoring expression of a plurality of genes in filamentous fungal cells.Type: ApplicationFiled: August 29, 2003Publication date: November 18, 2004Applicants: Novozymes Biotech, Inc., Novozymes A/S, Inc.Inventors: Randy M. Berka, Michael W. Rey, Jeffrey R. Shuster, Sakari Kauppinen, Ib Groth Clausen, Peter Bjarke Olsen
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Publication number: 20040197890Abstract: The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.Type: ApplicationFiled: December 17, 2003Publication date: October 7, 2004Inventors: Lene Lange, Wenping Wu, Dominique Aubert, Sara Landvik, Kirk Matthew Schnorr, Ib Groth Clausen
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Patent number: 6485954Abstract: The present invention relates to an enzyme with galactanase activity, a DNA construct encoding the enzyme with galactanase activity, a method of producing the enzyme, an enzyme composition comprising said enzyme with galactanase activity, and the use of said enzyme and enzyme composition for a number of industrial applications.Type: GrantFiled: November 28, 2000Date of Patent: November 26, 2002Assignee: Novozymes A/SInventors: Lene Venke Kofod, Markus Sakari Kauppinen, Lene Nonboe Andersen, Ib Groth Clausen, Anette Müllertz
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Publication number: 20020146721Abstract: The present invention relates to methods for monitoring differential expression of a plurality of genes in a first Bacillus cell relative to expression of the same genes in one or more second Bacillus cells using microarrays containing Bacillus genomic sequenced tags. The present invention also relates to computer readable media and computer-based systems. The present invention further relates to substrates containing an array of Bacillus licheniformis or Bacillus clausii GSTs.Type: ApplicationFiled: October 5, 2001Publication date: October 10, 2002Applicant: Novozymes Biotech, Inc.Inventors: Randy M. Berka, Ib Groth Clausen
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Patent number: 6331426Abstract: The invention relates to a method for modifying animal feed, in particular animal feed containing plant material such as soybean, by adding to the animal feed at least one galactanase enzym, to a method for obtaining a DNA sequence encoding a galactanase enzyme or a portion thereof, and to isolated polynucleotide molecules encoding polypeptides having galactanase activity.Type: GrantFiled: February 11, 2000Date of Patent: December 18, 2001Assignee: Novozymes A/SInventors: Mads Eskelund Bjørnvad, Ib Groth Clausen, Martin Schülein, Lisbeth Bech, Peter Rahbek Østergaard, Carsten Sjøholm
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Patent number: 6329185Abstract: The present invention relates to an enzyme with galactanase activity, a DNA construct encoding the enzyme, a method of producing the enzyme, an enzyme composition comprising the enzyme, and the use of the enzyme and enzyme composition for a number of industrial applications.Type: GrantFiled: August 4, 1998Date of Patent: December 11, 2001Assignee: Novozymes A/SInventors: Lene Venke Kofod, Markus Sakari Kauppinen, Lene Nonboe Andersen, Ib Groth Clausen
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Patent number: 6242237Abstract: The present invention relates to an enzyme with galactanase activity, a DNA construct encoding the enzyme with galactanase activity, a method of producing the enzyme, an enzyme composition comprising the enzyme with galactanase activity, and the use of the galactanase enzyme and enzyme composition for a number of industrial applications.Type: GrantFiled: August 21, 1998Date of Patent: June 5, 2001Assignee: Novo Nordisk A/SInventors: Lene Venke Kofod, Markus Sakari Kauppinen, Lene Nonboe Andersen, Ib Groth Clausen, Anette Müllertz
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Patent number: 6143545Abstract: The present invention relates to a method for reducing the content of phosphorous containing components in an edible oil comprising a high amount of non-hydratable phosphorus content, wherein said method comprises use of a phospholipase. Further the present invention relates to an enzyme with phospholipase activity, a cloned DNA sequence encoding the enzyme with phospholipase activity, a method of producing the enzyme, and the use of said enzyme for a number of industrial applications.Type: GrantFiled: September 1, 1999Date of Patent: November 7, 2000Assignee: Novo Nordisk A/SInventors: Ib Groth Clausen, Shamkant Anant Patkar, Kim Borch, Martin Barfoed, Kim Clausen, Claus Crone Fuglsang, Lone Dybdal, Torben Halkier
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Patent number: 6103505Abstract: The present invention relates to a method for reducing the content of phosphorous containing components in an edible oil comprising a high amount of non-hydratable phosphorous content, wherein the method comprises use of a phospholipase. Further the present invention relates to an enzyme with phospholipase activity, a cloned DNA sequence encoding the enzyme with phospholipase activity, a method of producing the enzyme, and the use of enzyme for a number of industrial applications.Type: GrantFiled: December 9, 1997Date of Patent: August 15, 2000Assignee: Novo Nordisk A/SInventors: Ib Groth Clausen, Shamkant Anant Patkar, Kim Borch, Martin Barfoed, Kim Clausen, Claus Crone Fuglsang, Lone Dybdal, Torben Halkier
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Patent number: 6074863Abstract: A lipase variant of a parent lipase comprising a trypsin-like catalytic triad including an active serine located in a predominantly hydrophobic, elongated binding pocket of the lipase molecule and, located in a critical position of a lipid contact zone of the lipase structure, an amino acid residue different from an aromatic amino acid residue, which amino acid residue interacts with a lipid substrate at or during hydrolysis, in which lipase variant said amino acid residue has been replaced by an aromatic amino acid residue so as to confer to the variant an increased specific activity as compared to that of the parent lipase. The parent lipase may be a C. antarctica lipase A essentially free from other substances from C. antarctica, which comprises the amino acid sequence shown in SEQ ID No. 2, or a variant of said lipase which (1) has lipase activity, (2) reacts with an antibody reactive with at least one epitope of C. antarctica lipase A having th eamino acid sequence SEQ ID No.Type: GrantFiled: December 22, 1994Date of Patent: June 13, 2000Assignee: Novo Nordisk A/SInventors: Allan Svendsen, Shamkant Anant Pathar, Michi Egel-Mitani, Kim Borch, Ib Groth Clausen, Mogens Trier Hansen