Abstract: A 3-cyano-2-ethoxy-9-(2-nitrobenzylidene)-4-(2-nitrophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridine compound, its synthesis, and its use as an antimicrobial agent.

Abstract: A therapeutic composition including phenolic compounds derived from Opuntia littoralis (OL) includes an extract of Opuntia littoralis and lutein. The Opuntia littoralis extract can be formed by extracting an Opuntia littoralis plant powder with an alcohol to provide an Opuntia littoralis alcohol extract (OLAE) including the phenolic compounds. In an embodiment, the therapeutic composition can be effectively used as an analgesic for the treatment of pain, as an anti-inflammatory, as a treatment for immunological disorders, and/or as a treatment for oxidant conditions.

Abstract: Herein disclosed are systems and methods related to delivery systems using solid source chemical fill vessels. The delivery system can include a vapor deposition reactor, two or more fill vessels, of which one of more can be remote from the vapor deposition reactor. Each fill vessel is configured to hold solid source chemical reactant therein. An interconnect line or conduit can fluidly connect the vapor deposition reactor with one or more of the fill vessels. A line heater can heat at least a portion of the interconnect line to at least a minimum line temperature.

Abstract: A spirooxindole nanoformulation includes a proniosome loaded with a spirooxindole derivative.

Abstract: A polymer electrolyte is disclosed that includes a polymer backbone containing a high dipole moiety and a low Tg moiety and a salt combined with the polymer. In addition to other possible benefits, the high dipole moiety in the polymer backbone may improve the conductivity of the polymer electrolyte. Additionally, the combination of a moiety with a high dipole moment with a moiety to impart low Tg may result in a high dielectric constant (for example, greater than 10).

Abstract: Bee venom nanoparticles and methods of synthesizing bee venom nanoparticles are provided. The bee venom nanoparticles may be synthesized by drying bee venom, suspending the dried bee venom in a solvent to form a first bee venom solution, spraying the first bee venom solution into boiling water under ultrasonic conditions to form a bee venom solution including the bee venom nanoparticles, stirring the bee venom solution including the bee venom nanoparticles, and freeze-drying the bee venom solution. The resulting nanoparticles may be used in pharmaceutical compositions, and may be useful for their antimicrobial activities.

Abstract: The technology searches for and activates an eSIM profile on a wireless communication device. One or more processors of the wireless communication device identify a geographic location associated with the device and at least one carrier that provides a wireless network communication service to the geographic location of the device. The device sends an inquiry to at least one subscription server associated with the at least carrier to determine if the at least one subscription server stores an electronic identity module (eSIM) profile associated with a unique identifier of the device. The inquiry includes the unique identifier of the device. The device receives a response from the at least one subscription server indicating that the at least one subscription server stores the eSIM profile associated with the unique identifier of the device. The device displays a prompt to a user indicating that the eSIM profile stored on the at least one subscription server is available for download.

Abstract: Methods and apparatus are provided for disposal of Fat, Oil and Grease (FOG) wastes in subterranean formations, and for disposal of low-density organic wastes in subterranean, brine-filled caverns.

Abstract: Systems and methods include a method for downhole leak detection and prediction in water injection wells. Bulk well operation information for one or more wells is accessed from a database. Real-time pressure and water rate information is received from surface and downhole gauges during operation of a water injection well. Engineered prediction-ready data is generated using the real-time pressure and water rate information by translating the bulk well operation information. Early signs of leakage at sub-surfaces of the water injection well are determined using the engineered prediction-ready data and wellbore dynamics of the water injection well. Information associated the early signs of leakage is provided based on the determining and for presentation to one or more users.

Abstract: Multiple sets of documents for different domains may be used to train multiple domain-specific models. A graph model may be generated to include nodes representing concepts included within the domain-specific models. A white space not including any nodes within the graph model may be identified. Analysis of the white space may be performed based on two or more nodes at periphery of the white space. Words/documents that cover the white space may be generated. Novelty of concepts may be readily assessed using the graph model/white space.

Abstract: Keywords obtained from a user and/or extracted from uploaded document(s) may be used to generate potential keywords. Documents may be identified based on the keywords and the potential keywords accepted by the user. A knowledge graph model representing the identified documents may be generated. The knowledge graph model may include document nodes representing the identified document and a search node representing the keywords. The relative position of the document nodes with respect to the search node may represent similarity between the corresponding documents and the keywords.

Abstract: Compositions of a glycolysis inhibitor and a mitochondrial complex I inhibitor or glucose-6-phosphate dehydrogenase inhibitor are described. Methods of treating metabolic disorders by administration of a composition comprising glycolysis inhibitor and a mitochondrial complex I inhibitor or glucose-6-phosphate dehydrogenase inhibitor are also described. Also described are methods of inhibiting the proliferation of cancer cells by administration of a therapeutically effective amount of a composition comprising a glycolysis inhibitor and a mitochondrial complex I inhibitor or glucose-6-phosphate dehydrogenase inhibitor.

Abstract: Inter-array cable (IAC) assemblies, systems, and methods are disclosed in which a conductive cable between two floating platforms, e.g., floating wind turbine platforms, is suspended below the sea surface and above the seabed. One or more buoyancy sections are included in the cable, which reduces the static tension on the connection at the floating platform by reducing the suspended cable weight, and which provides geometric flexibility, allowing the IAC to comply with platform motions.

Abstract: A well bridge plug assembly includes a sub body to be positioned in a well, the sub body including an internal fluid pathway extending from a downhole end of the sub body to an uphole end of the sub body. The sub body flows well fluid through the internal fluid pathway in an uphole direction from the downhole end toward the uphole end. A plug nose positioned at the downhole end of the sub body includes an aperture fluidly connected to the internal fluid pathway of the sub body. A flapper element in the internal fluid pathway moves between an open position and a closed position to selectively seal the internal fluid pathway from fluid flow, and a sealing element circumscribing a portion of the sub body selectively seals against a wall of a wellbore.

Abstract: Systems and methods include a method for downhole leak detection and prediction in water injection wells. Bulk well operation information for one or more wells is accessed from a database. Real-time pressure and water rate information is received from surface and downhole gauges during operation of a water injection well. Engineered prediction-ready data is generated using the real-time pressure and water rate information by translating the bulk well operation information. Early signs of leakage at sub-surfaces of the water injection well are determined using the engineered prediction-ready data and wellbore dynamics of the water injection well. Information associated the early signs of leakage is provided based on the determining and for presentation to one or more users.

Abstract: A computer system receives data obtained from multiple hydrocarbon wells. The data includes a first set of downhole temperature logs recorded before detection of one or more wellbore leaks in the multiple hydrocarbon wells. A second set of downhole temperature logs is recorded after detection of the one or more wellbore leaks. The computer system extracts multiple features from the data to generate an N-dimensional feature space. The computer system performs dimensionality reduction on the N-dimensional feature space to generate an M-dimensional feature space, wherein M is less than N. The computer system generates one or more machine learning models trained to determine the one or more wellbore leaks in the multiple hydrocarbon wells based on the M-dimensional feature space.

Abstract: A well bridge plug assembly includes a sub body to be positioned in a well, the sub body including an internal fluid pathway extending from a downhole end of the sub body to an uphole end of the sub body. The sub body flows well fluid through the internal fluid pathway in an uphole direction from the downhole end toward the uphole end. A plug nose positioned at the downhole end of the sub body includes an aperture fluidly connected to the internal fluid pathway of the sub body. A flapper element in the internal fluid pathway moves between an open position and a closed position to selectively seal the internal fluid pathway from fluid flow, and a sealing element circumscribing a portion of the sub body selectively seals against a wall of a wellbore.

Abstract: There is a need to increase protein synthesis in subjects receiving parenteral nutrition. The present disclosure provides oxidized glutathione (GSSG) or a GSSG analog as a supplement for parenteral nutrition to maintain, promote or increase protein synthesis in a subject receiving parenteral nutrition. The present disclosure also provides a parenteral nutrition solution as well as therapeutic uses of the parenteral nutrition supplement or the parenteral nutrition solution.

Abstract: A signal processing circuit is provided that generates output signals to be output from spatially different output ports based on bit combinations of an input word consisting of a plurality of bit signals. A distributed memory, a ROM and a DAC in which the signal processing circuit is used are also provided. A recognition circuit includes a serial port to which a bit signal is input and 2N output ports recognizing an input N-bit word and corresponding uniquely to 2N bit combinations. Output ports of the recognition circuit are connected to 2N input ports of an electric circuit. With no signal input to the recognition circuit, all outputs are constantly in a Low level state. In a case where a bit signal is input to the serial port of the recognition circuit, only one of the output ports corresponding to the bit combinations turns to a High level state.

Abstract: A signal processing circuit is provided that generates output signals to be output from spatially different output ports based on bit combinations of an input word consisting of a plurality of bit signals. A distributed memory, a ROM and a DAC in which the signal processing circuit is used are also provided. A recognition circuit includes a serial port to which a bit signal is input and 2N output ports recognizing an input N-bit word and corresponding uniquely to 2N bit combinations. Output ports of the recognition circuit are connected to 2N input ports of an electric circuit. With no signal input to the recognition circuit, all outputs are constantly in a Low level state. In a case where a bit signal is input to the serial port of the recognition circuit, only one of the output ports corresponding to the bit combinations turns to a High level state.