Patents by Inventor Ibrahim Hanouneh

Ibrahim Hanouneh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for diagnosing acute alcoholic hepatitis
    Patent number: 9541543
    Abstract: Various methods for determining whether a subject has alcoholic hepatitis are described. In one aspect, a method for determining whether a subject has alcoholic hepatitis is described. The method includes determining the levels of a trimethylamine in a biological sample obtained from the subject. The level of trimethylamine in the biological sample is compared to the control value, and the subject whose level of trimethylamine exceeds the control value is diagnosed as having alcoholic hepatitis. In another aspect of the present invention a method for assessing a subject as having alcoholic hepatitis (AH) includes determining the level of trimethylamine and the level of pentane in a biological sample obtained from the subject. A TAP score is determined based on the concentration of trimethylamine and the concentration of pentane. The subject is diagnosed as having alcoholic hepatitis if the TAP score exceeds a control value.
    Type: Grant
    Filed: January 13, 2015
    Date of Patent: January 10, 2017
    Assignee: The Cleveland Clinic Foundation
    Inventors: Raed Dweik, Ibrahim Hanouneh, Nizar Zein, David Grove, Frank S. Cikach, Jr.
  • METHOD FOR DIAGNOSING ACUTE ALCOHOLIC HEPATITIS
    Publication number: 20150140676
    Abstract: Various methods for determining whether a subject has alcoholic hepatitis are described. In one aspect, a method for determining whether a subject has alcoholic hepatitis is described. The method includes determining the levels of a trimethylamine in a biological sample obtained from the subject. The level of trimethylamine in the biological sample is compared to the control value, and the subject whose level of trimethylamine exceeds the control value is diagnosed as having alcoholic hepatitis. In another aspect of the present invention a method for assessing a subject as having alcoholic hepatitis (AH) includes determining the level of trimethylamine and the level of pentane in a biological sample obtained from the subject. A TAP score is determined based on the concentration of trimethylamine and the concentration of pentane. The subject is diagnosed as having alcoholic hepatitis if the TAP score exceeds a control value.
    Type: Application
    Filed: January 13, 2015
    Publication date: May 21, 2015
    Inventors: Raed Dweik, Ibrahim Hanouneh, Nizar Zein, David Grove, Frank S. Cikach, JR.
  • Method for diagnosing acute alcoholic hepatitis
    Patent number: 8932870
    Abstract: A method for determining whether a subject has alcoholic hepatitis is described. The method includes determining the levels of a trimethylamine in a biological sample obtained from the subject. The level of trimethylamine in the biological sample is compared to the control value, and the subject whose level of trimethylamine exceeds the control value is diagnosed as having alcoholic hepatitis.
    Type: Grant
    Filed: September 30, 2013
    Date of Patent: January 13, 2015
    Assignee: The Cleveland Clinic Foundation
    Inventors: Raed Dweik, Ibrahim Hanouneh, Nizar Zein, David Grove, Frank S. Cikach, Jr.
  • METHOD FOR DIAGNOSING ACUTE ALCOHOLIC HEPATITIS
    Publication number: 20140093970
    Abstract: A method for determining whether a subject has alcoholic hepatitis is described. The method includes determining the levels of a trimethylamine in a biological sample obtained from the subject. The level of trimethylamine in the biological sample is compared to the control value, and the subject whose level of trimethylamine exceeds the control value is diagnosed as having alcoholic hepatitis.
    Type: Application
    Filed: September 30, 2013
    Publication date: April 3, 2014
    Applicant: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Raed Dweik, Ibrahim Hanouneh, Nizar Zein, David Grove, Frank S. Cikach, JR.