Abstract: To provide a curing accelerator for an oxidatively polymerizable unsaturated resin which can decrease the amount of cobalt metal soap used and has curing performance equal to or higher than excellent curing performance of the cobalt metal soap, and a printing ink and a coating material using the same. A curing accelerator for an oxidatively polymerizable unsaturated resin including a manganese or cobalt complex (?) containing quinolinol compound ions represented by Structural Formula (1) as a ligand, and a printing ink and a coating material including the curing accelerator. In the formula, R1 is any of a hydrogen atom, a hydrocarbon group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, a hydroxyl group, an amino group, a nitro group, a nitroso group, a sulfo group, and a halogen atom, and n is an integer of 1 to 6.

Abstract: To provide a curing accelerator for an oxidatively polymerizable unsaturated resin which can decrease the amount of cobalt metal soap used and has curing performance equal to or higher than excellent curing performance of the cobalt metal soap, and a printing ink and a coating material using the same. A curing accelerator for an oxidatively polymerizable unsaturated resin including a manganese or cobalt complex (?) containing quinolinol compound ions represented by Structural Formula (1) as a ligand, and a printing ink and a coating material including the curing accelerator. In the formula, R1 is any of a hydrogen atom, a hydrocarbon group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, a hydroxyl group, an amino group, a nitro group, a nitroso group, a sulfo group, and a halogen atom, and n is an integer of 1 to 6.

Abstract: An oil-in-water emulsion that comprise a bacterial component as an active ingredient as well as essentially an oil, surfactant, and a stabilizer, and that can be used as an agent for immunotherapy, and the preparation therefor are provided.

Abstract: An oil-in-water emulsion that comprise a bacterial component as an active ingredient as well as essentially an oil, surfactant, and a stabilizer, and that can be used as an agent for immunotherapy, and the preparation therefor are provided.

Abstract: A sublimation printer device using a cut-sheet printing paper, including: a data processing section in charge of data processing for generating printing data; a printing processing section that performs image printing to the printing paper based on the printing data provided by the data processing section; a paper feed and eject section that feeds the printing paper to the printing processing section, and ejects the printing paper through with the image printing by the printing processing section; aperture detection means for detecting an aperture formed to a margin portion of the printing paper provided to the printing processing section by the paper feed and eject section; and a control section that exercises control over the other components in terms of operation.

Abstract: The present invention provides a novel method for inducing antigen-specific T cells. A method for inducing antigen-specific T cells in a patient comprising administering to said patient in need thereof composition (a) which comprises a therapeutically effective amount of an antigen protein or an antigen peptide as an active ingredient, and composition (b) which comprises a therapeutically effective amount of a cell wall skeleton integrant of the BCG strain of Mycobacterium bovis as an active ingredient, wherein composition (b) is administered in advance and then composition (a) is administered, and related pharmaceutical compositions are provided.

Abstract: An agent for cancer immunotherapy with independent use, containing bacterial components as an active ingredient, which induces cancer patients to exhibit immune responsiveness, as indicated by the increase of interferon-&ggr; and CD28 markers in peripheral blood, when administered to an immuno-competent patient intracutaneously.

Abstract: This invention relates to dendritic cells that are matured by utilizing a cell wall skeleton of a Gram positive bacteria-CWS and a process for maturing said cells, as well as a composition for accelerating the maturation of immature dendritic cells comprising a Gram positive bacteria-CWS as an essential component.

Abstract: The present invention provides a curable resin composition incorporating an oligomer containing blocked hydroxyl group, an epoxy-group containing compound, hydrolytic silyl-group containing compound, and a dissociation catalyst and/or curing catalyst, each possessing a specific molecular weight; a paint which uses this resin composition as a binder; and a coat-finishing method which coat-finishes any desired material using the aforementioned resin composition and paint. According to the present invention, it is possible to reduce viscosity, and consequently increase the coat non-volatile content and hence improve acid resistance, abrasion resistance, and the like. In addition, according to the present invention, it is possible to obtain a curable resin composition, paint using this curable resin composition, and coat-finishing method for this paint in which the aforementioned resin and paint have an extremely high utility and possess a high solid content wherein air bubbles and drip-runs are not generated.

Abstract: There are disclosed a high solids content resin composition excellent in solubility in an organic solvent, comprising an acrylic oligomer having a blocked hydroxyl group, a curing agent having a reactivity with a hydroxyl group and a dissociation or curing catalyst, and a high solids content type paint using the resin composition. There are also disclosed a coating process and a baking process comprising coating and baking the resin composition or the paint while rotating a material to be coated at an appropriate speed. The resin composition and the paint of the present invention have substantially no sagging and solvent popping. Further, the thus obtained paint film have improved smoothness, solvent resistance, weather resistance and resistance to scratching.

Abstract: There are disclosed amino acid derivatives represented by the following general formula (I): ##STR1## wherein L.sup.1 and L.sup.2 represent an amino acid residue etc., A.sup.1 and A.sup.3 represent C.dbd.O, A.sup.2 represents an alkylene group etc., m and n represent an integer of 1 to 5, V represents --NHC(.dbd.NH)NH.sub.2 etc., W represents --COOH etc., R.sup.1 and R.sup.2 represent hydrogen atom, alkyl group etc., R.sup.3 and R.sup.4 represent hydrogen etc. and X and Y represent --NH-- or --O-- and pharmaceutically acceptable salts thereof and agents for inhibiting tumor matastasis containing the compounds, and the amino acid derivatives exhibit high activity for inhibiting tumor metastasis and weak platelet aggregation inhibition activity and weak anticoagulation activity.

Abstract: There are disclosed a high solids content resin composition excellent in solubility in an organic solvent, comprising an acrylic oligomer having a blocked hydroxyl group, a curing agent having a reactivity with a hydroxyl group and a dissociation or curing catalyst, and a high solids content type paint using the resin composition. There are also disclosed a coating process and a baking process comprising coating and baking the resin composition or the paint while rotating a material to be coated at an appropriate speed. The resin composition and the paint of the present invention have substantially no sagging and solvent popping. Further, the thus obtained paint film have improved smoothness, solvent resistance, weather resistance and resistance to scratching.

Abstract: A peptide derivative containing 1 to 20 units of peptide unit represented by the following general formula [I] or a pharmaceutically acceptable salt thereof;[Z]--Arg--X--Asp--[Y] [I]wherein Arg represents L- or D-arginine residue, Asp represents L-aspartic acid residue, X represents L- or D-leucine, D-isoleucine, L- or D-norleucine, L- or D-phenylalanine, D-phenylglycine or D-alanine residue, and [Z] and [Y] each represents an amino acid or a peptide residue, which may be present or absent, selected from glycine, L-serine, L-threonine, L- and D-aspartic acid, L-alanine, L- and D-glutamic acid, L-proline residues and a peptide residue constituted by the foregoing amino acid residues, and a pharmaceutical composition comprising the peptide derivative. The composition of the present invention is useful as an agent for inhibiting tumor metastasis.

Abstract: A polypeptide comprising repeated amino acid sequences of a cell-adhesive protein represented by the formula:(Arg-Gly-Asp)n or (Tyr-Ile-Gly-Ser-Arg)nwherein n is a number ranging from 2 to 20; or a pharmaceutical acceptable salt thereof, which is valuable as an antimetastatic agent for cancer.

Abstract: This invention relates to a functional polypeptide containing the binding domain of human fibronectin and the heparin-binding domain of human fibronectin.

Abstract: A polypeptide comprising repeated amino acid sequences of a cell-adhesive protein represented by the formula:(Arg--Gly--Asp)nor(Tyr--Ile--Gly--Ser--Arg)nwherein n is a number ranging from 2 to 20; or a pharmaceutical acceptable salt thereof, which is valuable as an antimetastatic agent for cancer.

Abstract: A light source device comprises a lamp having a bar-shaped luminous body, a lamp housing having lamp supporting portions, a reflective curved interior surface for reflecting light from the lamp and an opening, and a light transmitting plate member which is composed of a lamination structure including a first diffusing plate, a linear Fresnel lens plate on which a plurality of striations are formed to extend in parallel with one another in a direction along the bar-shaped luminous body of the lamp and a second diffusing plate arranged in order, and attached to the lamp housing to be opposite to the reflective curved interior surface with the lamp between for covering the opening.

Abstract: A slow-releasing preparation comprises porous granules of deacetylated chitin as a carrier and a physiologically active substance contained in the granules. The slow-releasing prepartion can be embedded in a body for curing diseases.

Abstract: Muramyldipeptide derivatives represented by the formula: ##STR1## wherein Ala represents alanine; Acyl represents an acyl group; R.sub.1 and R.sub.2 each represents a hydrogen atom or, when taken together, may form an alkylidene group; R.sub.3 represents a hydrogen atom, an acyl group or an alkyl group; and R.sub.4 represents a hydrogen atom or an alkyl group. These compounds have excellent immunoadjuvant activity, prophylactic and therapeutic effects against microbial infections, and antitumor activity.

Abstract: A stable, storable pharmaceutical composition is provided which comprises a dehydrated solid mixture of microbial cell wall skeleton, vehicle oil, suspending agent and dispersing agent; wherein said microbial cell wall skeleton has adjuvant and antitumor activity. The composition is easily prepared, stable to long term storage, and easily reconstituted to form a homogeneous suspension which retains high potency.