Patents by Inventor Ichiro Matsumura

Ichiro Matsumura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assays for identifying functional alterations in the p53 tumor suppressor
    Patent number: 6429298
    Abstract: The present invention provides for various screening assays which are amenable to high throughput formats and identify a variety of useful mutations in tumor suppressor genes such as p53. Such mutations include those that activate the molecule, increase thermostability, increase transcriptional activity and facilitate resistance to inhibitory molecules. Also provided are methods of screening for accessory proteins that interact with tumor suppressors in both inhibitory and activating fashions, as well as cleavable mutants of p53 that are activated by viral proteases.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: August 6, 2002
    Assignee: Board of Regents, The University of Texas System
    Inventors: Andrew D. Ellington, Ichiro Matsumura