Abstract: Deimmunized botulinum toxin light chain (e.g., botulinum toxin serotype A light chains (BoNT/A-LC)) or fragments thereof are provided. Methods for treating or preventing diseases or disorders comprising administering to a subject a deimmunized botulinum toxin light chain (e.g., BoNT/A-LC) are provided.

Abstract: Provided herein, in aspects, are catalytically inactive BoNT-like toxins from Clostridium botulinum, serotype X (BoNT/NX) from Enterococcus faecium (BoNT/En) or from Paraclostridium bifermentans (BoNT/PMP1) and their use as delivery vehicles to deliver an agent (e.g., a therapeutic agent or a diagnostic agent) to a cell. Methods of treating a disease (e.g., botulism) are also provided.

Abstract: A light-emitting module of the present invention comprises: a light source in which an LED element is disposed on a substrate and electrodes electrically connected to the LED element are provided on the substrate; a metal plate on which the light source is disposed; lead wires connected to the electrodes directly or via other electrode pattern; and a housing made of resin fixed onto the metal plate and housing the light source therein. Moreover, the housing includes a hole opening above the light source, and includes at least one pair of protrusions that protrude facing one another inside the hole and apply a bias to the light source to press the light source onto a metal plate side.

Abstract: A light-emitting module of the present invention comprises: a light source in which an LED element is disposed on a substrate and electrodes electrically connected to the LED element are provided on the substrate; a metal plate on which the light source is disposed; lead wires connected to the electrodes directly or via other electrode pattern; and a housing made of resin fixed onto the metal plate and housing the light source therein. Moreover, the housing includes a hole opening above the light source, and includes at least one pair of protrusions that protrude facing one another inside the hole and apply a bias to the light source to press the light source onto a metal plate side.

Abstract: An inverter device operating under pulse width modulation (PWM) principle in which chopping pulse is formed by crossing points of a triangle waveform and a function waveform in order that pulse width of the inverter input current decreases towards later half of pulse train in each period of pulse repetition series so as to make the average input current for each one of the pulses substantially constant.

Abstract: An inverter device operating under pulse width modulation (PWM) principle in which chopping pulse is formed by crossing points of a triangle waveform and a function waveform in order that pulse width of the inverter input current decreases towards later half of pulse train in each period of pulse repetition series.