Patents by Inventor Ichiro Tokimitsu
Ichiro Tokimitsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7939563Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid). When the preventive or remedy for hypertension according to the present invention is administered, ferulic acid exists in the blood for a long period of time, thereby continuously suppressing a blood pressure rise. Moreover, the hypertension preventive or remedy according to the present invention has reduced in bitterness peculiar to ferulic acid, which enables patients to take it continuously.Type: GrantFiled: April 15, 2005Date of Patent: May 10, 2011Assignee: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Patent number: 7750053Abstract: Products and compositions for preventing or reducing the severity of hypertension. These products contain (a) ferulic acid or a ferulate ester, and (b) caffeic acid and/or a chlorogenic acid. The preventive or remedy can suppress a rise in blood pressure and alleviate hypertension, and is usable as a food.Type: GrantFiled: August 7, 2001Date of Patent: July 6, 2010Assignee: KAO CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Patent number: 7534815Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid).Type: GrantFiled: March 29, 2004Date of Patent: May 19, 2009Assignee: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Patent number: 7351436Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.Type: GrantFiled: July 25, 2003Date of Patent: April 1, 2008Assignee: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20060233897Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.Type: ApplicationFiled: June 14, 2006Publication date: October 19, 2006Applicant: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Patent number: 7033623Abstract: Provided is a mineral absorption enhancing method comprising administering an effective amount of a green coffee bean extract. The present invention can relieve mineral deficiency by using a mineral absorption enhancer which is excellent in safety and has an excellent mineral absorption enhancing effect.Type: GrantFiled: November 24, 2003Date of Patent: April 25, 2006Assignee: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Patent number: 6991812Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.Type: GrantFiled: September 4, 2001Date of Patent: January 31, 2006Assignee: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20050281897Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.Type: ApplicationFiled: August 24, 2005Publication date: December 22, 2005Applicant: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20050215632Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid). When the preventive or remedy for hypertension according to the present invention is administered, ferulic acid exists in the blood for a long period of time, thereby continuously suppressing a blood pressure rise. Moreover, the hypertension preventive or remedy according to the present invention has reduced in bitterness peculiar to ferulic acid, which enables patients to take it continuously.Type: ApplicationFiled: April 15, 2005Publication date: September 29, 2005Applicant: KAO CORPORATIONInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20050197394Abstract: There are provided an endurance improver and an anti-fatigue agent for broadly-defined exercises including sports requiring endurance and labors requiring repeated muscle exertions. The present endurance improver and anti-fatigue agent contain diacylglycerol as an active ingredient.Type: ApplicationFiled: February 24, 2005Publication date: September 8, 2005Applicant: KAO CORPORATIONInventors: Takatoshi Murase, Ushio Harada, Noriko Osaki, Ichiro Tokimitsu
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Patent number: 6894077Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid). When the preventive or remedy for hypertension according to the present invention is administered, ferulic acid exists in the blood for a long period of time, thereby continuously suppressing a blood pressure rise. Moreover, the hypertension preventive or remedy according to the present invention has reduced in bitterness peculiar to ferulic acid, which enables patients to take it continuously.Type: GrantFiled: June 5, 2002Date of Patent: May 17, 2005Assignee: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20040198807Abstract: Products and compositions for preventing or reducing the severity of hypertension. These products contain (a) ferulic acid or a ferulate ester, and (b) caffeic acid and/or a chlorogenic acid. The preventive or remedy can suppress a rise in blood pressure and alleviate hypertension, and is usable as a food.Type: ApplicationFiled: April 19, 2004Publication date: October 7, 2004Applicant: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20040192773Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): 1Type: ApplicationFiled: March 29, 2004Publication date: September 30, 2004Applicant: KAO CORPORATIONInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20040151790Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.Type: ApplicationFiled: July 25, 2003Publication date: August 5, 2004Applicant: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20040105908Abstract: Provided is a mineral absorption enhancing method comprising administering an effective amount of a green coffee bean extract.Type: ApplicationFiled: November 24, 2003Publication date: June 3, 2004Applicant: KAO CORPORATIONInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20040043057Abstract: Products and compositions for preventing or reducing the severity of hypertension. These products contain (a). ferulic acid or a ferulate ester, and (b) caffeic acid and/or a chlorogenic acid. The preventive or remedy can suppress a rise in blood pressure and alleviate hypertension, and is usable as a food.Type: ApplicationFiled: August 4, 2003Publication date: March 4, 2004Applicant: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20030220398Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): 1Type: ApplicationFiled: June 5, 2002Publication date: November 27, 2003Applicant: KAO CORPORATIONInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20020054923Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.Type: ApplicationFiled: September 4, 2001Publication date: May 9, 2002Applicant: Kao CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Publication number: 20020051810Abstract: Products and compositions for preventing or reducing the severity of hypertension. These products contain (a) ferulic acid or a ferulate ester, and (b) caffeic acid and/or a chlorogenic acid. The preventive or remedy can suppress a rise in blood pressure and alleviate hypertension, and is usable as a food.Type: ApplicationFiled: August 7, 2001Publication date: May 2, 2002Applicant: KAO CORPORATIONInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
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Patent number: 6310100Abstract: A method for treating hypertension, a cardiac disease, or a cerebrovascular disease comprising administration of ferulic acid or a derivative thereof, to a subject in need of treatment. Therapeutic compositions comprising ferulic acid and its derivatives may comprise pharmaceutical products, nutritional supplements or products, and foods. Such compositions may further comprising diglycerides in combination with ferulic acid and its derivatives.Type: GrantFiled: September 22, 2000Date of Patent: October 30, 2001Assignee: KAO CorporationInventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu