Patents by Inventor Ichiro Tokimitsu

Ichiro Tokimitsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7939563
    Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid). When the preventive or remedy for hypertension according to the present invention is administered, ferulic acid exists in the blood for a long period of time, thereby continuously suppressing a blood pressure rise. Moreover, the hypertension preventive or remedy according to the present invention has reduced in bitterness peculiar to ferulic acid, which enables patients to take it continuously.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: May 10, 2011
    Assignee: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Patent number: 7750053
    Abstract: Products and compositions for preventing or reducing the severity of hypertension. These products contain (a) ferulic acid or a ferulate ester, and (b) caffeic acid and/or a chlorogenic acid. The preventive or remedy can suppress a rise in blood pressure and alleviate hypertension, and is usable as a food.
    Type: Grant
    Filed: August 7, 2001
    Date of Patent: July 6, 2010
    Assignee: KAO Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Patent number: 7534815
    Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid).
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: May 19, 2009
    Assignee: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Patent number: 7351436
    Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.
    Type: Grant
    Filed: July 25, 2003
    Date of Patent: April 1, 2008
    Assignee: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20060233897
    Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.
    Type: Application
    Filed: June 14, 2006
    Publication date: October 19, 2006
    Applicant: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Patent number: 7033623
    Abstract: Provided is a mineral absorption enhancing method comprising administering an effective amount of a green coffee bean extract. The present invention can relieve mineral deficiency by using a mineral absorption enhancer which is excellent in safety and has an excellent mineral absorption enhancing effect.
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: April 25, 2006
    Assignee: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Patent number: 6991812
    Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.
    Type: Grant
    Filed: September 4, 2001
    Date of Patent: January 31, 2006
    Assignee: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20050281897
    Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.
    Type: Application
    Filed: August 24, 2005
    Publication date: December 22, 2005
    Applicant: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20050215632
    Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid). When the preventive or remedy for hypertension according to the present invention is administered, ferulic acid exists in the blood for a long period of time, thereby continuously suppressing a blood pressure rise. Moreover, the hypertension preventive or remedy according to the present invention has reduced in bitterness peculiar to ferulic acid, which enables patients to take it continuously.
    Type: Application
    Filed: April 15, 2005
    Publication date: September 29, 2005
    Applicant: KAO CORPORATION
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20050197394
    Abstract: There are provided an endurance improver and an anti-fatigue agent for broadly-defined exercises including sports requiring endurance and labors requiring repeated muscle exertions. The present endurance improver and anti-fatigue agent contain diacylglycerol as an active ingredient.
    Type: Application
    Filed: February 24, 2005
    Publication date: September 8, 2005
    Applicant: KAO CORPORATION
    Inventors: Takatoshi Murase, Ushio Harada, Noriko Osaki, Ichiro Tokimitsu
  • Patent number: 6894077
    Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): wherein, R1 and R2 are the same or different and each independently represents hydrogen, alkyl, alkenyl, cycloalkyl, cycloalkenyl, alkoxyalkyl, aryl, alkylaryl, aralkyl, or acyl, R3 represents hydroxyl, ester bond residue, or amide bond residue, R4 represents ester bond residue or amide bond residue, or a pharmaceutically acceptable salt thereof (except ferulic acid). When the preventive or remedy for hypertension according to the present invention is administered, ferulic acid exists in the blood for a long period of time, thereby continuously suppressing a blood pressure rise. Moreover, the hypertension preventive or remedy according to the present invention has reduced in bitterness peculiar to ferulic acid, which enables patients to take it continuously.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: May 17, 2005
    Assignee: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20040198807
    Abstract: Products and compositions for preventing or reducing the severity of hypertension. These products contain (a) ferulic acid or a ferulate ester, and (b) caffeic acid and/or a chlorogenic acid. The preventive or remedy can suppress a rise in blood pressure and alleviate hypertension, and is usable as a food.
    Type: Application
    Filed: April 19, 2004
    Publication date: October 7, 2004
    Applicant: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20040192773
    Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): 1
    Type: Application
    Filed: March 29, 2004
    Publication date: September 30, 2004
    Applicant: KAO CORPORATION
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20040151790
    Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.
    Type: Application
    Filed: July 25, 2003
    Publication date: August 5, 2004
    Applicant: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20040105908
    Abstract: Provided is a mineral absorption enhancing method comprising administering an effective amount of a green coffee bean extract.
    Type: Application
    Filed: November 24, 2003
    Publication date: June 3, 2004
    Applicant: KAO CORPORATION
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20040043057
    Abstract: Products and compositions for preventing or reducing the severity of hypertension. These products contain (a). ferulic acid or a ferulate ester, and (b) caffeic acid and/or a chlorogenic acid. The preventive or remedy can suppress a rise in blood pressure and alleviate hypertension, and is usable as a food.
    Type: Application
    Filed: August 4, 2003
    Publication date: March 4, 2004
    Applicant: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20030220398
    Abstract: Provided is a method of treating hypertension, which comprises administering an effective amount of a compound represented by the following formula (1) or (2): 1
    Type: Application
    Filed: June 5, 2002
    Publication date: November 27, 2003
    Applicant: KAO CORPORATION
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20020054923
    Abstract: The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension.
    Type: Application
    Filed: September 4, 2001
    Publication date: May 9, 2002
    Applicant: Kao Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Publication number: 20020051810
    Abstract: Products and compositions for preventing or reducing the severity of hypertension. These products contain (a) ferulic acid or a ferulate ester, and (b) caffeic acid and/or a chlorogenic acid. The preventive or remedy can suppress a rise in blood pressure and alleviate hypertension, and is usable as a food.
    Type: Application
    Filed: August 7, 2001
    Publication date: May 2, 2002
    Applicant: KAO CORPORATION
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu
  • Patent number: 6310100
    Abstract: A method for treating hypertension, a cardiac disease, or a cerebrovascular disease comprising administration of ferulic acid or a derivative thereof, to a subject in need of treatment. Therapeutic compositions comprising ferulic acid and its derivatives may comprise pharmaceutical products, nutritional supplements or products, and foods. Such compositions may further comprising diglycerides in combination with ferulic acid and its derivatives.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: October 30, 2001
    Assignee: KAO Corporation
    Inventors: Atsushi Suzuki, Ryuji Ochiai, Ichiro Tokimitsu