Abstract: It is presented a computer-implemented method for estimating narrowings in arteries of a heart based on a sample myocardial perfusion imaging (S-MPI) data set using an artificial neural network (ANN). The method comprises receiving, in a data processing apparatus, the S-MPI data and a request, determining, in the data processing apparatus, an estimate quantitative coronary angiography (E-QCA) data set based on the S-MPI data set using the ANN, wherein the ANN is trained using a reference MPI (R-MPI) data set, a reference quantitative coronary angiography (R-QCA) data set and a reference invasive measurement (R-IM) data set, wherein each record in the R-MPI data set has a corresponding record in the R-QCA data set and a corresponding record in the R-IM data set, respectively, and transmitting, from the data processing apparatus, the E-QCA data set in response to the request.

Abstract: A system and method for determining or estimating the presence and effect of light-attenuating inhomogeneities in tissue when performing medical treatment or diagnostics using optical members in tissue. The system and method comprising inserting a plurality of optical members into the tissue, and then measuring by emitting light through a sub-set of optical members at a time, while measuring the light collected by another sub-set of optical members. Combining said measurement data with a model for light propagation in tissue, and setting up a system of equations. Solving the unknown attenuation values from said system of equations.

Abstract: A system and method for determining or estimating the presence and effect of light-attenuating inhomogeneities in tissue when performing medical treatment or diagnostics using optical members in tissue. The system and method comprising inserting a plurality of optical members into the tissue, and then measuring by emitting light through a sub-set of optical members at a time, while measuring the light collected by another sub-set of optical members. Combining said measurement data with a model for light propagation in tissue, and setting up a system of equations. Solving the unknown attenuation values from said system of equations.