Patents by Inventor Idlir Liko

Idlir Liko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dendritic detergents for the analysis of proteins by mass spectrometry
    Patent number: 12122805
    Abstract: A method of detecting a protein by mass spectrometry comprises: providing a solution comprising a dendritic detergent and a protein; providing a mass spectrometer comprising a nanoelectrospray ionisation source, a mass analyser and a detector; vaporising the solution using the nanoelectrospray ionisation source; ionising the protein; resolving the ionised protein using the mass analyser; and detecting the resolved protein using the detector. A method of extracting a membrane protein from its native membrane comprises: providing a membrane protein in its native membrane; contacting the membrane protein with a dendritic detergent. Dendritic detergents for use in the methods are also provided.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: October 22, 2024
    Assignees: OXFORD UNIVERSITY INNOVATION LIMITED, FREIE UNIVERSITÄT BERLIN
    Inventors: Carol V. Robinson, Idlir Liko, Hsin-Yung Yen, Kevin Pagel, Rainer Haag, Svenja Christina Ehrmann, Leonhard Hagen Urner
  • DENDRITIC DETERGENTS FOR THE ANALYSIS OF PROTEINS BY MASS SPECTROMETRY
    Publication number: 20210188902
    Abstract: A method of detecting a protein by mass spectrometry comprises: providing a solution comprising a dendritic detergent and a protein; providing a mass spectrometer comprising a nanoelectrospray ionisation source, a mass analyser and a detector; vaporising the solution using the nanoelectrospray ionisation source; ionising the protein; resolving the ionised protein using the mass analyser; and detecting the resolved protein using the detector. A method of extracting a membrane protein from its native membrane comprises: providing a membrane protein in its native membrane; contacting the membrane protein with a dendritic detergent. Dendritic detergents for use in the methods are also provided.
    Type: Application
    Filed: September 4, 2019
    Publication date: June 24, 2021
    Inventors: Carol V. Robinson, Idlir Liko, Hsin-Yung Yen, Kevin Pagel, Rainer Haag, Svenja Christina Ehrmann, Leonhard Hagen Urner