Abstract: A motion sensor device comprises: a reverse electrowetting-on-dielectric (REWOD) generator configured to generate alternating current (AC) based on motion; a motion sensor configured to measure motion data; and a wireless motion sensor read-out circuit coupled to the REWOD generator and the motion sensor, the wireless motion sensor read-out circuit configured to transmit the motion data and operate on the AC from the REWOD generator.

Abstract: In alternative embodiments, provided are products of manufacture and kits, and methods, for delivering macromolecules, including nucleic acids such as DNA and RNA, including genes and protein-encoding nucleic acids, to the skin, or the dermis or epidermis, and mucosa. In alternative embodiments, provided are products of manufacture and kits, and methods, for detecting macromolecules, including nucleic acids such as DNA and RNA, including genes and protein-encoding nucleic acids, in skin, epidermal or mucosal cells. In alternative embodiments, exemplary products of manufacture are physically flexible nanodelivery devices that are wearable, e.g., they can be worn as patches on the skin or mucosa. In alternative embodiments, nanodelivery devices provided herein are fabricated in a microelectrode—microfluidic—nanochannel configuration which can precisely deliver cargo into the ‘touched’ cells upon localized and safe-voltage electroporation.