Patents by Inventor Ignacio ALONSO SILVA

Ignacio ALONSO SILVA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCEDURE FOR OBTAINING GADOTERATE MEGLUMINE FROM HIGH-PURITY TETRAXETAN (DOTA) AND ITS USE IN THE PREPARATION OF INJECTABLE GALENICAL FORMULATIONS
    Publication number: 20230248851
    Abstract: The present invention refers to a process for obtaining gadoterate meglumine from high purity tetraxetan (DOTA) which does not require the use of organic solvents and optimizes the conditions of the synthetic process. The tetraxetan from which the gadoterate meglumine is obtained by a synthetic process that includes a purification step in which at least one electrodialysis is performed. This procedure makes it possible to obtain a tetraxetan and a gadoterate meglumine with minimal amounts of impurities.
    Type: Application
    Filed: June 10, 2021
    Publication date: August 10, 2023
    Inventors: Ignacio ALONSO SILVA, Juan Andrés CERECEDA PÉREZ, Felix Ramón MARTÍN MARTÍN, Maria Ángeles REGUEIRA GÓMEZ, Roberto CHICHARRO MARTÍN, ÁIvaro GARCÍA RAMOS, Irene GARCÍA SALADO, Vicente MONTIEL LEGUEY, Eduardo EXPÓSITO RODRÍGUEZ, Vicente GARCÍA GARCÍA, David VALERO VALERO, Alfonso SÁEZ FÉRNANDEZ, Francisco GALLUD MARTINÉZ