Abstract: A device configured for antimicrobial, in particular bacteriostatic or bactericidal, activity, and a method for manufacturing the device. The device includes a device body having a surface. The device body is configured to anchor thermal nanoparticles supporting optical resonance, in particular localized surface plasmon resonance, at its surface. The device body includes thermal nanoparticles supporting optical resonance, in particular localized surface plasmon resonance, bonded to the surface of the device body. The thermal nanoparticles are capable of increasing their temperature by light irradiation in a wavelength range that matches with the wavelength of the optical resonance, in particular localized surface plasmon resonance, of the thermal nanoparticles. The device body also includes an antimicrobial substance that is releasable from the device body.

Abstract: The present invention relates to a microcomplex containing a modified nanoparticle adsorbed on a host microparticle and to a process to obtain it. The microcomplex is particularly useful for photoepilation. The present invention also relates to a composition containing the microcomplex and to the method for enhanced photoepilation based on the microcomplexes.

Abstract: The present invention relates to a composition for topical application on skin for photoepilation comprising nanocomplexes which comprise a nanoparticle supporting an LSP resonance which is coated with at least a chemical compound, wherein said chemical compound is selected from the group consisting of polyionic polymers, heterobifunctional compound of the surface assembled monolayer type, antibodies and their mixtures. The present invention also relates to a photoepilation method which comprises the steps of (i) applying to the skin surface the composition for topical application of the present invention, and (ii) applying a radiation to said surface of the skin.

Abstract: The present invention relates to a microcomplex containing a modified nanoparticle adsorbed on a host microparticle and to a process to obtain it. The microcomplex is particularly useful for photoepilation. The present invention also relates to a composition containing the microcomplex and to the method for enhanced photoepilation based on the microcomplexes.

Abstract: The present invention relates to a composition for topical application on skin for photoepilation comprising nanocomplexes which comprise a nanoparticle supporting an LSP resonance which is coated with at least a chemical compound, wherein said chemical compound is selected from the group consisting of polyionic polymers, heterobifunctional compound of the surface assembled monolayer type, antibodies and their mixtures. The present invention also relates to a photoepilation method which comprises the steps of (i) applying to the skin surface the composition for topical application of the present invention, and (ii) applying a radiation to said surface of the skin.

Abstract: A particulate complex including a nucleic acid and a biodegradable cationized polyhydroxylated molecule, wherein said molecule has a charge up to approximately 1.0 meq/g.

Abstract: A particulate complex is provided comprising a particulate complex comprising a nucleic acid and a biodegradable cationized polyhydroxylated molecule, wherein the polyhydroxylated molecule has a charge up to approximately 1.0 meq/g.

Abstract: The invention relates to an ionic conjugate, which is stable in a biological medium, and which is comprised of a particle vector with at least one cationic, nonliquid, hydrophilic nucleus and of polyanionic oligonucleotides. The invention further concerns the pharmaceutical compositions containing these conjugates and the use of a particle vector to carry the oligonucleotides to the cells.

Abstract: A novel method for the mucosal administration of a substance to a mammal is provided. The method comprises contacting a mucosal surface of the mammal with the substance in combination with a Biovector. The Biovector has a core that comprises a natural polymer, or a derivative or a hydrolysate of a natural polymer, or a mixture thereof. A preferred natural polymer is a polysaccharide or an oligosaccharide. The core is optionally coated with an amphiphilic compound, such as a lipid.

Abstract: A novel method for the mucosal administration of a substance to a mammal is provided. The method comprises contacting a mucosal surface of the mammal with the substance in combination with a Biovector. The Biovector has a core that comprises a natural polymer, or a derivative or a hydrolysate of a natural polymer, or a mixture thereof. A preferred natural polymer is a polysaccharide or an oligosaccharide. The core is optionally coated with an amphiphilic compound, such as a lipid.

Abstract: A synthetic particulate vector comprising a non-liquid hydrophilic nucleus and an outer layer at least partially consisting of amphiphilic compounds, which is combined with the nucleus by hydrophobic interactions and/or ionic bonds. A process for preparing a particulate vector by encapsulating an ionizable active principle, vectors obtained according to such a process, and pharmaceutical, cosmeticological and food compositions comprising such vectors are also disclosed.

Abstract: A biodegradable particulate vector for transporting biologically active molecules is prepared containing a nucleus formed of a cross-linked polysaccharide or oligosaccharide matrix having grafted ionic ligands, a layer of fatty acid compounds covalently bonded to the nucleus and a layer of phospholipids hydrophobically bonded to the layer of fatty acid compounds. Dextran, cellulose or starch may be cross-linked with epichlorohydrin to form a cross-linked polysaccharide matrix. Ionic ligands may be grafted using an acidic compound such as succinic acid, phosphoric acid or phosphorous oxychloride, or a basic compound such as choline, hydroxycholine, 2-(dimethylamino)ethanol or 2-(dimethylamino) ethylamine fastened onto the grafted acidic compound. Phosphoric acid or phosphorous oxychloride in one step provide both cross-linking and ionic ligands. Co-cross-linking can be obtained using a protein such as keratin, collagen or elastase.

Abstract: A biodegradable particulate vector for transporting biologically active molecules is prepared containing a nucleus for containing a biologically active molecule, a first layer of fatty acid compounds covalently bonded to the nucleus and a second layer of phospholipids hydrophobically bonded to the first layer. The nucleus is between 10 nm and 10 .mu.m in size and is formed of a cross-linked polysaccharide or oligosaccharide matrix onto which ionic ligands are uniformly grafted. The cross-linked polysaccharide may be dextran, cellulose or starch cross-linked with epichlorohydrin. The ligand may be an acidic compound selected from succinic acid, phosphoric acid, citric acid, glycine, alanine, glutamic acid and aspartic acid, or a basic compound such as choline, hydroxycholine, 2-(dimethylamino)ethanol or 2-(dimethylamino)ethylamine fastened onto the matrix via the acidic compound. The polysaccharide or oligosaccharide may be co-cross-linked with a protein such as keratin/collagen or elastase.