Patents by Inventor Ignacio M. Larrinua

Ignacio M. Larrinua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9688983
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: June 27, 2017
    Assignee: Dow AgroSciences LLC
    Inventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango, Matthew J. Henry, Aaron T. Woosley, Murugesan Rangasamy
  • Patent number: 9487798
    Abstract: DIG-10 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
    Type: Grant
    Filed: May 17, 2013
    Date of Patent: November 8, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
  • Publication number: 20160304900
    Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.
    Type: Application
    Filed: June 28, 2016
    Publication date: October 20, 2016
    Inventors: Ignacio M. Larrinua, Donald Merlo, Avutu Sambi Reddy, Arvind Kumar ThirumalaiswamySekhar, Aaron T. Woosley
  • Patent number: 9447153
    Abstract: The present invention includes domain I modifications that improve various attributes of various Coleopteran-active Cry proteins. These attributes can include improved target pest spectrum, potency, and insect resistance management. The subject modifications can affect protoxin activation and the efficiency of pore formation, which can lead to enhanced insect intoxication.
    Type: Grant
    Filed: September 17, 2012
    Date of Patent: September 20, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: Timothy D. Hey, Ignacio M. Larrinua, Kenneth E. Narva
  • Patent number: 9427003
    Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.
    Type: Grant
    Filed: April 16, 2012
    Date of Patent: August 30, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: Ignacio M. Larrinua, Donald J. Merlo, Avutu S. Reddy, Arvind Kumar ThirumalaiswamySekhar, Aaron T. Woosley
  • Patent number: 9284573
    Abstract: The present invention includes modified, insecticidal B.t. Cry1Ca proteins, including the proteins designated herein as DIG-109 and DIG-152, as well as variants of DIG-109 and DIG-152, nucleic acids encoding these proteins, methods of controlling pests using the proteins, methods of producing the proteins in transgenic host cells, and transgenic plants that produce the proteins. The DIG-109 and DIG-152 proteins comprise chimeric peptides composed of a core toxin segment of B.t. Cry1Ca and a Cry1Ab protoxin segment. Insecticidally active variants of the DIG-109 and DIG-152 proteins are also described.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: March 15, 2016
    Assignee: Dow AgroSciences LLC
    Inventors: Thomas Meade, Stephanie L. Burton, Kenneth Narva, Aaron T. Woosley, Timothy D. Hey, Ignacio M. Larrinua
  • Patent number: 9102946
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: August 11, 2015
    Assignee: Dow AgroSciences LLC
    Inventors: Kenneth Narva, Chaoxian Geng, Monica B. Olson, Huarong Li, Ignacio M. Larrinua, Navin Elango
  • Patent number: 9050363
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: June 9, 2015
    Assignee: Dow AgroSciences LLC
    Inventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango, Matthew J. Henry
  • Patent number: 9012722
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: April 21, 2015
    Assignee: Dow AgroSciences LLC
    Inventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango
  • Patent number: 8987552
    Abstract: Nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests are disclosed. Methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby are also disclosed.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: March 24, 2015
    Assignee: Dow AgroSciences, LLC.
    Inventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango
  • Publication number: 20140298536
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Application
    Filed: December 13, 2013
    Publication date: October 2, 2014
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango, Matthew J. Henry, Aaron T. Woosley, Murugesan Rangasamy
  • Patent number: 8697642
    Abstract: DIG-10 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: April 15, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
  • Publication number: 20130247254
    Abstract: DIG-10 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
    Type: Application
    Filed: May 17, 2013
    Publication date: September 19, 2013
    Applicant: Dow AgroSciences LLC
    Inventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
  • Patent number: 8476226
    Abstract: DIG-10 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: July 2, 2013
    Assignee: Dow AgroSciences
    Inventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
  • Patent number: 8461422
    Abstract: DIG-5 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: June 11, 2013
    Assignee: Dow Agrosciences LLC
    Inventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
  • Publication number: 20130025006
    Abstract: The present invention includes modified, insecticidal B.t. Cry1Ca proteins, including the proteins designated herein as DIG-109 and DIG-152, as well as variants of DIG-109 and DIG-152, nucleic acids encoding these proteins, methods of controlling pests using the proteins, methods of producing the proteins in transgenic host cells, and transgenic plants that produce the proteins. The DIG-109 and DIG-152 proteins comprise chimeric peptides composed of a core toxin segment of B.t. Cry1Ca and a Cry1Ab protoxin segment. Insecticidally active variants of the DIG-109 and DIG-152 proteins are also described.
    Type: Application
    Filed: December 16, 2010
    Publication date: January 24, 2013
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Thomas Meade, Stephanie L. Burton, Kenneth Narva, Aaron T. Woosley, Timothy D. Hey, Ignacio M. Larrinua
  • Patent number: 8304605
    Abstract: DIG-11 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
    Type: Grant
    Filed: June 14, 2010
    Date of Patent: November 6, 2012
    Assignee: Dow AgroSciences, LLC.
    Inventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
  • Publication number: 20120266335
    Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.
    Type: Application
    Filed: April 16, 2012
    Publication date: October 18, 2012
    Applicant: DOW AGROSCIENCES LLC
    Inventors: IGNACIO M. LARRINUA, DONALD J. MERLO, AVUTU S. REDDY, ARVIND KUMAR THIRUMALAISWAMYSEKHAR, AARON T. WOOSLEY
  • Patent number: 8269069
    Abstract: The present invention includes domain I modifications that improve various attributes of various Coleopteran-active Cry proteins. These attributes can include improved target pest spectrum, potency, and insect resistance management. The subject modifications can affect protoxin activation and the efficiency of pore formation, which can lead to enhanced insect intoxication.
    Type: Grant
    Filed: July 30, 2009
    Date of Patent: September 18, 2012
    Assignee: Dow AgroSciences, LLC
    Inventors: Kenneth Narva, Ignacio M. Larrinua, Timothy D. Hey
  • Publication number: 20120174260
    Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.
    Type: Application
    Filed: December 30, 2011
    Publication date: July 5, 2012
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango