Patents by Inventor Ignacio M. Larrinua
Ignacio M. Larrinua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9688983Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: December 13, 2013Date of Patent: June 27, 2017Assignee: Dow AgroSciences LLCInventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango, Matthew J. Henry, Aaron T. Woosley, Murugesan Rangasamy
-
Patent number: 9487798Abstract: DIG-10 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.Type: GrantFiled: May 17, 2013Date of Patent: November 8, 2016Assignee: Dow AgroSciences LLCInventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
-
Publication number: 20160304900Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.Type: ApplicationFiled: June 28, 2016Publication date: October 20, 2016Inventors: Ignacio M. Larrinua, Donald Merlo, Avutu Sambi Reddy, Arvind Kumar ThirumalaiswamySekhar, Aaron T. Woosley
-
Patent number: 9447153Abstract: The present invention includes domain I modifications that improve various attributes of various Coleopteran-active Cry proteins. These attributes can include improved target pest spectrum, potency, and insect resistance management. The subject modifications can affect protoxin activation and the efficiency of pore formation, which can lead to enhanced insect intoxication.Type: GrantFiled: September 17, 2012Date of Patent: September 20, 2016Assignee: Dow AgroSciences LLCInventors: Timothy D. Hey, Ignacio M. Larrinua, Kenneth E. Narva
-
Patent number: 9427003Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.Type: GrantFiled: April 16, 2012Date of Patent: August 30, 2016Assignee: Dow AgroSciences LLCInventors: Ignacio M. Larrinua, Donald J. Merlo, Avutu S. Reddy, Arvind Kumar ThirumalaiswamySekhar, Aaron T. Woosley
-
Patent number: 9284573Abstract: The present invention includes modified, insecticidal B.t. Cry1Ca proteins, including the proteins designated herein as DIG-109 and DIG-152, as well as variants of DIG-109 and DIG-152, nucleic acids encoding these proteins, methods of controlling pests using the proteins, methods of producing the proteins in transgenic host cells, and transgenic plants that produce the proteins. The DIG-109 and DIG-152 proteins comprise chimeric peptides composed of a core toxin segment of B.t. Cry1Ca and a Cry1Ab protoxin segment. Insecticidally active variants of the DIG-109 and DIG-152 proteins are also described.Type: GrantFiled: December 16, 2010Date of Patent: March 15, 2016Assignee: Dow AgroSciences LLCInventors: Thomas Meade, Stephanie L. Burton, Kenneth Narva, Aaron T. Woosley, Timothy D. Hey, Ignacio M. Larrinua
-
Patent number: 9102946Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: December 30, 2011Date of Patent: August 11, 2015Assignee: Dow AgroSciences LLCInventors: Kenneth Narva, Chaoxian Geng, Monica B. Olson, Huarong Li, Ignacio M. Larrinua, Navin Elango
-
Patent number: 9050363Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: December 30, 2011Date of Patent: June 9, 2015Assignee: Dow AgroSciences LLCInventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango, Matthew J. Henry
-
Patent number: 9012722Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: GrantFiled: December 30, 2011Date of Patent: April 21, 2015Assignee: Dow AgroSciences LLCInventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango
-
Patent number: 8987552Abstract: Nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests are disclosed. Methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby are also disclosed.Type: GrantFiled: December 30, 2011Date of Patent: March 24, 2015Assignee: Dow AgroSciences, LLC.Inventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango
-
Publication number: 20140298536Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: ApplicationFiled: December 13, 2013Publication date: October 2, 2014Applicant: DOW AGROSCIENCES LLCInventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango, Matthew J. Henry, Aaron T. Woosley, Murugesan Rangasamy
-
Patent number: 8697642Abstract: DIG-10 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.Type: GrantFiled: June 14, 2010Date of Patent: April 15, 2014Assignee: Dow AgroSciences, LLC.Inventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
-
Publication number: 20130247254Abstract: DIG-10 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.Type: ApplicationFiled: May 17, 2013Publication date: September 19, 2013Applicant: Dow AgroSciences LLCInventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
-
Patent number: 8476226Abstract: DIG-10 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.Type: GrantFiled: June 14, 2010Date of Patent: July 2, 2013Assignee: Dow AgroSciencesInventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
-
Patent number: 8461422Abstract: DIG-5 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.Type: GrantFiled: June 14, 2010Date of Patent: June 11, 2013Assignee: Dow Agrosciences LLCInventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
-
Publication number: 20130025006Abstract: The present invention includes modified, insecticidal B.t. Cry1Ca proteins, including the proteins designated herein as DIG-109 and DIG-152, as well as variants of DIG-109 and DIG-152, nucleic acids encoding these proteins, methods of controlling pests using the proteins, methods of producing the proteins in transgenic host cells, and transgenic plants that produce the proteins. The DIG-109 and DIG-152 proteins comprise chimeric peptides composed of a core toxin segment of B.t. Cry1Ca and a Cry1Ab protoxin segment. Insecticidally active variants of the DIG-109 and DIG-152 proteins are also described.Type: ApplicationFiled: December 16, 2010Publication date: January 24, 2013Applicant: DOW AGROSCIENCES LLCInventors: Thomas Meade, Stephanie L. Burton, Kenneth Narva, Aaron T. Woosley, Timothy D. Hey, Ignacio M. Larrinua
-
Patent number: 8304605Abstract: DIG-11 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.Type: GrantFiled: June 14, 2010Date of Patent: November 6, 2012Assignee: Dow AgroSciences, LLC.Inventors: Justin M. Lira, Kenneth Narva, Aaron T. Woosley, Ignacio M. Larrinua, Timothy D. Hey
-
Publication number: 20120266335Abstract: The invention provides synthetic nucleic acid sequences encoding proteins of interest that are particularly adapted to express well in plants. The claimed synthetic sequences utilize plant-optimized codons roughly in the same frequency at which they are utilized, on average, in genes naturally occurring in the plant species. The invention further includes synthetic DNA sequence for herbicide tolerance, water and/or heat stress tolerance, healthy oil modifications and for transformation marker genes and selectable marker genes are used. DNA construct and transgenic plants containing the synthetic sequences are taught as are methods and compositions for using the plants in agriculture.Type: ApplicationFiled: April 16, 2012Publication date: October 18, 2012Applicant: DOW AGROSCIENCES LLCInventors: IGNACIO M. LARRINUA, DONALD J. MERLO, AVUTU S. REDDY, ARVIND KUMAR THIRUMALAISWAMYSEKHAR, AARON T. WOOSLEY
-
Patent number: 8269069Abstract: The present invention includes domain I modifications that improve various attributes of various Coleopteran-active Cry proteins. These attributes can include improved target pest spectrum, potency, and insect resistance management. The subject modifications can affect protoxin activation and the efficiency of pore formation, which can lead to enhanced insect intoxication.Type: GrantFiled: July 30, 2009Date of Patent: September 18, 2012Assignee: Dow AgroSciences, LLCInventors: Kenneth Narva, Ignacio M. Larrinua, Timothy D. Hey
-
Publication number: 20120174260Abstract: This disclosure concerns nucleic acid molecules and methods of use thereof for control of coleopteran pests through RNA interference-mediated inhibition of target coding and transcribed non-coding sequences in coleopteran pests. The disclosure also concerns methods for making transgenic plants that express nucleic acid molecules useful for the control of coleopteran pests, and the plant cells and plants obtained thereby.Type: ApplicationFiled: December 30, 2011Publication date: July 5, 2012Applicant: DOW AGROSCIENCES LLCInventors: Kenneth Narva, Huarong Li, Chaoxian Geng, Ignacio M. Larrinua, Monica B. Olson, Navin Elango