Patents by Inventor Ignacio Munoz

Ignacio Munoz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Zinc finger protein compositions for modulation of huntingtin (Htt)
    Patent number: 11421007
    Abstract: The present disclosure is in the field of modulation of Htt gene expression and HTT protein levels.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: August 23, 2022
    Assignees: Sangamo Therapeutics, Inc., CHDI Foundation, Inc.
    Inventors: Steven Froelich, Ignacio Munoz-Sanjuan, Edward J. Rebar, Bryan Zeitler, H. Steve Zhang
  • Zinc finger protein compositions for modulation of huntingtin (Htt)
    Patent number: 11279739
    Abstract: The present disclosure is in the field of modulation of Htt gene expression and HTT protein levels.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: March 22, 2022
    Assignees: Sangamo Therapeutics, Inc., CHDI Foundation, Inc.
    Inventors: Steven Froelich, Ignacio Munoz-Sanjuan, Edward J. Rebar, Bryan Zeitler, H. Steve Zhang
  • Methods and compositions for treating Huntington's Disease
    Patent number: 11110154
    Abstract: Disclosed herein are methods and compositions for treating or preventing Huntington's Disease.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: September 7, 2021
    Assignees: Sangamo Therapeutics, Inc., CHDI Foundation, Inc.
    Inventors: Steven Froelich, Seung Kwak, Ignacio Munoz-Sanjuan, H. Steve Zhang
  • Tool coupling
    Patent number: 11034031
    Abstract: A tool coupling includes a first tool part and a second tool part, the second tool part being movable in relation to the first tool part. The tool coupling further includes a first base part for detachably retaining the first tool part and a second base part movable in relation to the first base part for detachably retaining the second tool part. The first base part has a pusher movable in relation to the first base part for detaching the first tool part and the second base part has a cap movable in relation to the second base part for detaching the second tool part.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: June 15, 2021
    Assignees: FUNDACIÓN TECNALIA RESEARCH & INNOVATION, UNIVERISAD DE CÓRDOBA, SERVICIO ANDALUZ DE SALUD, UNIVERISAD DE MÁLAGA
    Inventors: Julius Klein Hubert, Asier Fernández Iribar, Rafael Medina Carnicer, Rafael Muñoz Salinas, Enrique Bauzano Núñez, Mᵃ Carmen López Casado, Víctor Fernando Muñoz Martínez, María José Requena Tapia, José Eduardo Arjona Berral, Rosa María Paredes Esteban, Ángel Salvatierra Velázquez, Ignacio Muñoz Carvajal, Javier Briceño Delgado
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10457675
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use.
    Type: Grant
    Filed: July 30, 2018
    Date of Patent: October 29, 2019
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • ZINC FINGER PROTEIN COMPOSITIONS FOR MODULATION OF HUNTINGTIN (HTT)
    Publication number: 20190322711
    Abstract: The present disclosure is in the field of modulation of Htt gene expression and HTT protein levels.
    Type: Application
    Filed: April 17, 2019
    Publication date: October 24, 2019
    Inventors: Steven Froelich, Ignacio Munoz-Sanjuan, Edward J. Rebar, Bryan Zeitler, H. Steve Zhang
  • Preparation of artificial tissues by means of tissue engineering using fibrin and agarose biomaterials
    Publication number: 20190247541
    Abstract: The present invention is encompassed in the field of biomedicine and more specifically tissue engineering. It relates specifically to an in vitro method for preparing an artificial tissue, to the artificial tissue obtainable by said method and to the use of this artificial tissue to partially or completely increase, restore or replace the functional activity of a damaged tissue or organ.
    Type: Application
    Filed: March 8, 2019
    Publication date: August 15, 2019
    Applicant: UNIVERSIDAD DE GRANADA
    Inventors: Miguel Alaminos Mingorance, José Ignacio Muñoz Ávila, Miguel González Andrades, Antonio Campos Muñoz, Ingrid Johanna Garzón Bello
  • TOOL COUPLING
    Publication number: 20190217483
    Abstract: A tool coupling includes a first tool part and a second tool part, the second tool part being movable in relation to the first tool part. The tool coupling further includes a first base part for detachably retaining the first tool part and a second base part movable in relation to the first base part for detachably retaining the second tool part. The first base part has a pusher movable in relation to the first base part for detaching the first tool part and the second base part has a cap movable in relation to the second base part for detaching the second tool part.
    Type: Application
    Filed: June 23, 2017
    Publication date: July 18, 2019
    Applicants: Fundación Tecnalia Research & Innovation, Universsidad de Córdoba, Servicio Andaluz de Salud, Universidad de Málaga
    Inventors: Julius KLEIN HUBERT, Asier FERNÁNDEZ IRIBAR, Rafael MEDINA CARNICER, Rafael MUÑOZ SALINAS, Enrique BAUZANO NÚÑEZ, Mª Carmen LÓPEZ CASADO, Víctor Fernando MUÑOZ MARTÍNEZ, María José REQUENA TAPIA, José Eduardo ARJONA BERRAL, Rosa María PAREDES ESTEBAN, Ángel SALVATIERRA VELÁZQUEZ, Ignacio MUÑOZ CARVAJAL, Javier BRICEÑO DELGADO
  • Methods and compositions for treating HIV-related disorders
    Patent number: 10258621
    Abstract: Certain adjunctive therapies comprising a kynurenine-3-monooxygenase inhibitor and an antiviral agent for treating HIV-related disorders are provided herein. These disorders include AIDS dementia complex, AIDS-induced encephalopathy, HIV-associated neurocognitive disorder, asymptomatic neurocognitive impairment, minor neurocognitive disorder, minor cognitive motor disorder, vacuolar myelopathy, peripheral neuropathies, and polymyositis. Also provided are pharmaceutical compositions comprising a kynurenine-3-monooxygenase inhibitor and an antiviral agent.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: April 16, 2019
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Leticia Toledo-Sherman
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20190062321
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use.
    Type: Application
    Filed: July 30, 2018
    Publication date: February 28, 2019
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • SPIKE PORT FOR MEDICAL SOLUTION BAG ASSEMBLY AND RELATED METHODS
    Publication number: 20190046407
    Abstract: A molded spike port including a first portion defining a first chamber, a plug disposed in the first chamber and configured to form a seal with the first portion, a second portion defining a second chamber, the second portion including a sealing ring configured to seal the spike port to a spike, a tip configured to be inserted into a fluid bag, the tip comprising a membrane, and a wall between the first portion and the second portion, wherein the wall is configured to break when the first portion is twisted relative to the second portion.
    Type: Application
    Filed: August 9, 2017
    Publication date: February 14, 2019
    Inventors: Kahina Rabia, Makenzie Jones, Christopher Yim Chau, Eduardo Ignacio Muñoz Laverde
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10106535
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: October 23, 2018
    Assignee: CHDI FOUNDATION, INC.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10105363
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: January 20, 2017
    Date of Patent: October 23, 2018
    Assignee: CHDI foundation, Inc.
    Inventors: Celia Dominguez, Vahri Beaumont, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Alan F. Haughan, Christopher A. Luckhurst, Michael Wall, Gilles Raphy, Beth Thomas
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 10065948
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, or pharmaceutically acceptable salts thereof, compositions thereof, and methods of their use. The condition or disorder mediated by HDAC comprises a neurodegenerative pathology. Accordingly, also provided is a method of treating a neurodegenerative pathology mediated by HDAC in a subject in need of such a treatment, comprising administering to the subject a therapeutically effective amount of at least one compound, or pharmaceutically acceptable salt thereof, described herein.
    Type: Grant
    Filed: June 1, 2015
    Date of Patent: September 4, 2018
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Christopher A. Luckhurst, Daniel R. Allen, Gilles Raphy, Perla Breccia, Alan F. Haughan, Grant Wishart, Samantha J. Hughes, Rebecca E. Jarvis, Huw D. Vater, Stephen D. Penrose, Michael Wall, Andrew J. Stott, Elizabeth A. Saville-Stones
  • Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
    Patent number: 9981918
    Abstract: Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.
    Type: Grant
    Filed: August 28, 2012
    Date of Patent: May 29, 2018
    Assignee: CHDI Foundation, Inc.
    Inventors: Leticia M. Toledo-Sherman, Celia Dominguez, Michael Prime, Peter Johnson, Ignacio Muñoz-Sanjuán, Stephen Martin Courtney, William Mitchell, Christopher John Brown, Paula C. De Aguiar Pena
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20170305900
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: April 7, 2017
    Publication date: October 26, 2017
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Daniel R. Allen, Alan F. Haughan, Perla Breccia, Huw D. Vater, Andrew J. Stott, Stephen D. Penrose, Michael Wall, Elizabeth A. Saville-Stones, Grant Wishart, Samantha J. Hughes
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 9783488
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: March 10, 2014
    Date of Patent: October 10, 2017
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Ignacio Muñoz-Sanjuán, Michel Maillard, Gilles Raphy, Alan F. Haughan, Christopher A. Luckhurst, Rebecca E. Jarvis, Roland W. Bürli, Perla Breccia, Grant Wishart, Samantha J. Hughes, Daniel R. Allen, Stephen D. Penrose
  • Histone deacetylase inhibitors and compositions and methods of use thereof
    Patent number: 9765054
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: September 19, 2017
    Assignee: CHDI Foundation, Inc.
    Inventors: Roland W. Bürli, Andrew J. Stott, Perla Breccia, Celia Dominguez, Ignacio Muñoz-Sanjuàn, Christopher A. Luckhurst, Samantha J. Hughes, Alan F. Haughan
  • System for continuous measuring, recording and monitoring of the splanchnic tissue perfusion and the pulmonary physiological dead space, and use thereof
    Patent number: 9730614
    Abstract: The present invention relates to a new system for measuring, recording and monitoring the splanchnic tissue perfusion and the pulmonary physiological dead space in an automated way, both continuously and intermittently, and in real time, which is easy to manage and generates information easy to interpret. Said system comprises at least four measuring devices of medical parameters, connected to a device receiving, converting, storing, integrating, processing, and allowing the management and display of the data recorded in the measurements and the parameters estimated by the same. For this purpose, said device comprises a specific computer program of estimation of parameters related to the measurement of the splanchnic tissue perfusion and the pulmonary physiological dead space, from the data derived from the measuring devices. Likewise, the present invention is related to the use of a device for measuring, recording and monitoring of the splanchnic tissue perfusion and the pulmonary physiological dead space.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: August 15, 2017
    Inventor: Juan Ignacio Muñoz Bonet
  • HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20170224684
    Abstract: Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
    Type: Application
    Filed: January 20, 2017
    Publication date: August 10, 2017
    Inventors: Celia Dominguez, Vahri Beaumont, Ignacio Muñoz-Sanjuán, Roland W. Bürli, Alan F. Haughan, Christopher A. Luckhurst, Michael Wall, Gilles Raphy, Beth Thomas