Patents by Inventor Ignacio Segarra

Ignacio Segarra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COCHLEATE FORMULATIONS
    Publication number: 20140220109
    Abstract: A process for producing a small-sized, lipid-based cochleates. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.
    Type: Application
    Filed: December 31, 2013
    Publication date: August 7, 2014
    Applicant: Rutgers, The State University of New Jersey
    Inventors: Leila Zarif, Tuo Jin, Ignacio Segarra, Raphael J. Mannino
  • NOVEL COCHLEATE FORMULATIONS
    Publication number: 20120294901
    Abstract: A process for producing a small-sized, lipid-based cochleates. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.
    Type: Application
    Filed: April 6, 2012
    Publication date: November 22, 2012
    Applicants: University of Medicine and Dentistry of New Jersey, BioDelivery Sciences International, Inc.
    Inventors: Leila Zarif, Tuo Jin, Ignacio Segarra, Raphael J. Mannino
  • Novel cochleate formulations
    Publication number: 20090028904
    Abstract: A process for producing a small-sized, lipid-based cochleate. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.
    Type: Application
    Filed: April 23, 2008
    Publication date: January 29, 2009
    Applicant: BioDelivery Sciences International, Inc.
    Inventors: Leila Zarif, Tuo Jin, Ignacio Segarra, Raphael J. Mannino
  • Novel cochleate formulations
    Publication number: 20050186265
    Abstract: A process for producing a small-sized, lipid-based cochleates. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.
    Type: Application
    Filed: January 18, 2005
    Publication date: August 25, 2005
    Applicant: University of Medicine and Dentistry of New Jersey
    Inventors: Leila Zarif, Tuo Jin, Ignacio Segarra, Raphael Mannino
  • Novel hydrogel-isolated cochleate formulations, process of preparation and their use for the delivery of biologically relevant molecules
    Publication number: 20030228355
    Abstract: A process for producing a small-sized, lipid-based cochleate. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.
    Type: Application
    Filed: April 23, 2003
    Publication date: December 11, 2003
    Applicants: BioDelivery Sciences International, Inc., University of Medicine and Dentistry of New Jersey
    Inventors: Leila Zarif, Tuo Jin, Ignacio Segarra, Raphael J. Mannino
  • Hydrogel-isolated cochleate formulations, process of preparation and their use for the delivery of biologically relevant molecules
    Patent number: 6592894
    Abstract: A process for producing a small-sized, lipid-based cochleate. Cochleates are derived from liposomes which are suspended in an aqueous two-phase polymer solution, enabling the differential partitioning of polar molecule based-structures by phase separation. The liposome-containing two-phase polymer solution, treated with positively charged molecules such as Ca2+ or Zn2+, forms a cochleate precipitate of a particle size less than one micron. The process may be used to produce cochleates containing biologically relevant molecules.
    Type: Grant
    Filed: July 11, 2000
    Date of Patent: July 15, 2003
    Assignees: BioDelivery Sciences International, Inc., University of Medicine and Dentistry of New Jersey
    Inventors: Leila Zarif, Tuo Jin, Ignacio Segarra, Raphael J. Mannino