Patents by Inventor Igor A. Kaltashov

Igor A. Kaltashov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for delivering agents to the central nervous system
    Patent number: 9950075
    Abstract: The invention in some aspects provides compounds useful for targeting bacterial infections. In some embodiments, the compounds comprise a transferrin receptor ligand covalently linked to a bactericidal agent. In some embodiments, the bactericidal agent is a bactericidal peptide, such as a glycoside hydrolase (e.g., lysozyme).
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 24, 2018
    Assignee: The University of Massachusetts
    Inventors: Son N. Nguyen, Cedric E. Bobst, Igor A. Kaltashov
  • COMPOSITIONS AND METHODS FOR DELIVERING AGENTS TO THE CENTRAL NERVOUS SYSTEM
    Publication number: 20170065720
    Abstract: The invention in some aspects provides compounds useful for targeting bacterial infections. In some embodiments, the compounds comprise a transferrin receptor ligand covalently linked to a bactericidal agent. In some embodiments, the bactericidal agent is a bactericidal peptide, such as a glycoside hydrolase (e.g., lysozyme).
    Type: Application
    Filed: March 14, 2014
    Publication date: March 9, 2017
    Applicant: University of Massachusetts
    Inventors: Son N. Nguyen, Cedric E. Bobst, Igor A. Kaltashov
  • Temperature-controlled electrospray ionization source and methods of use thereof
    Patent number: 8766179
    Abstract: Disclosed herein is an electrospray ionization source that provides improved temperature control compared to prior sources. A combination of a continuous flow sample design and the use of a long heat shield combine to improve thermal control and reduce memory effects observed with prior designs. The temperature-controlled source is particularly useful for the study of biomolecules, particularly the study of protein aggregation.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: July 1, 2014
    Assignee: The University of Massachusetts
    Inventors: Igor A. Kaltashov, Guanbo Wang, Rinat R. Abzalimov
  • TEMPERATURE-CONTROLLED ELECTROSPRAY IONIZATION SOURCE AND METHODS OF USE THEREOF
    Publication number: 20130234017
    Abstract: Disclosed herein is an electrospray ionization source that provides improved temperature control compared to prior sources. A combination of a continuous flow sample design and the use of a long heat shield combine to improve thermal control and reduce memory effects observed with prior designs. The temperature-controlled source is particularly useful for the study of biomolecules, particularly the study of protein aggregation.
    Type: Application
    Filed: January 7, 2013
    Publication date: September 12, 2013
    Applicant: THE UNIVERSITY OF MASSACHUSETTS
    Inventors: Igor A. Kaltashov, Guanbo Wang, Rinat R. Abzalimov