Patents by Inventor Igor Bacik

Igor Bacik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • liver stage antigens
    Patent number: 8318183
    Abstract: The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.
    Type: Grant
    Filed: March 11, 2010
    Date of Patent: November 27, 2012
    Assignees: Seattle Biomedical Research Institute, The United States of America, as Represented by the Secretary of the Army, on Behalf of the Walter Reed Army Institute of Research, Philadelphia Health & Education Corporation
    Inventors: Patrick Duffy, Stefan H. I. Kappe, Urszula Krzych, Donald G. Heppner, Lawrence W. Bergman, Vladislav A. Malkov, Alice Tarun, Jason P. Wendler, Igor Bacik
  • PLASMODIUM LIVER STAGE ANTIGENS
    Publication number: 20100166794
    Abstract: The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs:1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.
    Type: Application
    Filed: March 11, 2010
    Publication date: July 1, 2010
    Applicants: SEATTLE BIOMEDICAL RESEARCH INSTITUTE, The USA, as Represented by the Secretary of the Army,on Behalf of the Walter Reed, Philadelphia Health & Education Corporation, d/b/a Drexel University College of Medicine "DUCOM"
    Inventors: Patrick Duffy, Stefan H.I. Kappe, Urszula Krzych, Donald G. Heppner, JR., Lawrence W. Bergman, Vladislav A. Malkov, Alice Tarun, Jason W. Wendler, Igor Bacik
  • Plasmodium liver stage antigens
    Patent number: 7722889
    Abstract: The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: May 25, 2010
    Assignees: Seattle Biomedical Research Institute, The United States of America as represented by the Secretary of the Army
    Inventors: Patrick Duffy, Urszula Krzych, Donald G. Heppner, Jr., Vladislav A. Malkov, Jason W. Wendler, Igor Bacik
  • PLASMODIUM LIVER STAGE ANTIGENS
    Publication number: 20090017055
    Abstract: The invention provides isolated liver stage Plasmodium polypeptides comprising an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-48 and immunogenic derivatives thereof. The invention also provides isolated nucleic acid molecules encoding the liver stage Plasmodium polypeptides of the invention, compositions comprising one or more liver stage Plasmodium polypeptides of the invention, methods for inducing an immune response against the liver stage Plasmodium polypeptides, and methods for treating and diagnosing liver stage malaria.
    Type: Application
    Filed: September 29, 2006
    Publication date: January 15, 2009
    Applicants: SEATTLE BIOMEDICAL RESEARCH INSTITUTE, REED ARMY INSTITUTE OF RESEARCH, PHILADELPHIA HEALTH & EDUCATION CORPORATION, D/B/A/ DREXEL UNIVERSITY COLLEGE OF MEDICINE DUCOM
    Inventors: Patrick Duffy, Stefan H. I. Kappe, Urszula Krzych, Donald G. Heppner, JR., Lawrence W. Bergman, Vladislav A. Malkov, Alice Tarun, Jason W. Wendler, Igor Bacik
  • Immunogenic chimeras comprising nucleic acid sequences encoding endoplasmic reticulum signal sequence peptides and at least one other peptide, and their uses in vaccines and disease treatments
    Patent number: 5856187
    Abstract: Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: January 5, 1999
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Nicholas P. Restifo, Steven A. Rosenberg, Jack R. Bennick, Igor Bacik, Jonathan W. Yewdell
  • Immunogenic chimeras comprising nucleic acid sequences encoding endoplasmic reticulum signal sequence peptides and at least one other peptide, and their uses in vaccines and disease treatments
    Patent number: 5846540
    Abstract: Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 8, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Nicholas P. Restifo, Steven A. Rosenberg, Jack R. Bennink, Igor Bacik, Jonathan W. Yewdell
  • Immunogenic chimeras comprising nucleic acid sequences encoding endoplasmic reticulum signal sequence peptides and at least one other peptide, and their uses in vaccines and disease treatments
    Patent number: 5733548
    Abstract: Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs capable of directing host organism synthesis of immunogenic chimeric proteins which can be used as immunogens, as vaccines, or in methods of treatment for cancer, infectious diseases, or autoimmune diseases.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: March 31, 1998
    Assignee: The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services
    Inventors: Nicholas P. Restifo, Steven A. Rosenberg, Jack R. Bennink, Igor Bacik, Jonathan W. Yewdell