Patents by Inventor Igor Edmundo Paolo D'Angelo

Igor Edmundo Paolo D'Angelo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multivalent heteromultimer scaffold design and constructs
    Patent number: 9499605
    Abstract: Provided herein are multifunctional heteromer proteins. In specific embodiments is a heteromultimer that comprises: at least two monomeric proteins, wherein each monomeric protein comprises at least one cargo polypeptide, attached to a transporter polypeptide, such that said monomeric proteins associate to form the heteromultimer. These therapeutically novel molecules comprise monomers that function as scaffolds for the conjugation or fusion of therapeutic molecular entities resulting in the creation of bispecific or multivalent molecular species.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: November 22, 2016
    Assignee: Zymeworks Inc.
    Inventors: Surjit Bhimarao Dixit, Igor Edmundo Paolo D'Angelo, David Kai Yuen Poon
  • MULTIVALENT HETEROMULTIMER SCAFFOLD DESIGN AND CONSTRUCTS
    Publication number: 20120244577
    Abstract: Provided herein are multifunctional heteromer proteins. In specific embodiments is a heteromultimer that comprises: at least two monomeric proteins, wherein each monomeric protein comprises at least one cargo polypeptide, attached to a transporter polypeptide, such that said monomeric proteins associate to form the heteromultimer. These therapeutically novel molecules comprise monomers that function as scaffolds for the conjugation or fusion of therapeutic molecular entities resulting in the creation of bispecific or multivalent molecular species.
    Type: Application
    Filed: March 2, 2012
    Publication date: September 27, 2012
    Applicant: Zymeworks Inc.
    Inventors: Surjit Bhimarao Dixit, Igor Edmundo Paolo D'Angelo, David Kai Yuen Poon