Patents by Inventor Igor Entin

Igor Entin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140079813
    Abstract: Provided are methods, systems and kits for predicting post-relapse survival of a cancer patient and for identifying cancer genes predictive of the post-relapse survival of the patient. Values representing gene expression levels of a group of genes associated with survival of the cancer cells are determined using gene expression profiling platforms and a plurality of probe sets that hybridize to one or more of the genes in the group. A predictive model establishes a predictive value based on the weighted contribution of each gene associated with survival of the cancer cells to risk of death for the cancer patient and imports expression values of the genes in the group that is indicative of a risk of death for the relapsed patient.
    Type: Application
    Filed: April 27, 2012
    Publication date: March 20, 2014
    Inventors: Joshua Epstein, Shmuel Yaccoby, John D. Shaughnessy, JR., Barthel Barlogie, Igor Entin
  • Publication number: 20110269638
    Abstract: Provided are methods, systems and kits for predicting post-relapse survival of a cancer patient and for identifying cancer genes predictive of the post-relapse survival of the patient. Values representing gene expression levels of a group of genes associated with survival of the cancer cells are determined using gene expression profiling platforms and a plurality of probe sets that hybridize to one or more of the genes in the group. A predictive model establishes a predictive value based on the weighted contribution of each gene associated with survival of the cancer cells to risk of death for the cancer patient and imports expression values of the genes in the group that is indicative of a risk of death for the relapsed patient.
    Type: Application
    Filed: April 29, 2011
    Publication date: November 3, 2011
    Inventors: Joshua Epstein, Shmuel Yaccoby, John D. Shaughnessy, JR., Barthel Barlogie, Igor Entin
  • Patent number: 7395112
    Abstract: A method of treating tumor tissue of an individual is provided. The method is effected by applying to cells of the tumor tissue electrical field pulses having a strength, a repetition frequency and a pulse width selected capable of inducing endocytosis mediated cell death thereby treating the tumor tissue.
    Type: Grant
    Filed: June 9, 2002
    Date of Patent: July 1, 2008
    Assignee: Ramot At Tel Aviv University Ltd.
    Inventors: Yona Keisari, Rafl Korenstein, Igor Entin, Yosef Rosemberg
  • Publication number: 20080132963
    Abstract: A method of treating tumor tissue of an individual is provided. The method is effected by applying to cells of the tumor tissue electrical field pulses having a strength, a repetition frequency and a pulse width selected capable of inducing endocytosis mediated cell death thereby treating the tumor tissue.
    Type: Application
    Filed: February 1, 2008
    Publication date: June 5, 2008
    Applicant: Ramot At Tel Aviv University Ltd.
    Inventors: Yona Keisari, Rafi Korenstein, Igor Entin, Yosef Rosemberg
  • Publication number: 20040158288
    Abstract: A method of treating tumor tissue of an individual is provided. The method is effected by applying to cells of the tumor tissue electrical field pulses having a strength, a repetition frequency and a pulse width selected capable of inducing endocytosis mediated cell death thereby treating the tumor tissue.
    Type: Application
    Filed: November 28, 2003
    Publication date: August 12, 2004
    Inventors: Yona Keisari, Rafl Korenstein, Igor Entin, Yosef Rosemberg
  • Publication number: 20020198567
    Abstract: There is provided a method for introducing a therapeutic agent into a membrane vesicle, cell, or tissue by exposing the membrane vesicle, cell, or tissue to a low electric field in the presence of the therapeutic agent in an extracellular compartment of the membrane vesicle, cell, or tissue. Also provided is therapy including a low electric field alone or in combination with a therapeutic agent.
    Type: Application
    Filed: June 7, 2001
    Publication date: December 26, 2002
    Inventors: Yona Keisari, Rafi Korenstein, Igor Entin, Yosef Rosemberg