Patents by Inventor Igor Gonda

Igor Gonda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190328731
    Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: July 9, 2019
    Publication date: October 31, 2019
    Applicants: ARADIGM CORPORATION, OREGON STATE UNIVERSITY
    Inventors: Igor GONDA, James BLANCHARD, David C. CIPOLLA, Luiz Eduardo Moreira BERMUDEZ
  • Patent number: 10376508
    Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: August 13, 2019
    Assignees: ARADIGM CORPORATION, OREGON STATE UNIVERSITY
    Inventors: Igor Gonda, James Blanchard, David C. Cipolla, Luiz Eduardo Moreira Bermudez
  • Patent number: 9987227
    Abstract: Methods for formulating and compositions of immediate and sustained release liposomal products which comprise a surfactant that interacts with liposomes to effect drug release therefrom, and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: June 5, 2018
    Assignee: ARADIGM CORPORATION
    Inventors: David C. Cipolla, Igor Gonda
  • Patent number: 9968555
    Abstract: Methods for formulating a liposome comprised of a surfactant and a cryopreservative that can be frozen for long term stability, and upon thawing provides an immediate and sustained release delivery profile. Specific liposome formulations include anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: February 11, 2015
    Date of Patent: May 15, 2018
    Assignee: ARADIGM CORPORATION
    Inventors: David C. Cipolla, Igor Gonda
  • Publication number: 20180092912
    Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: November 22, 2017
    Publication date: April 5, 2018
    Applicants: ARADIGM CORPORATION, OREGON STATE UNIVERSITY
    Inventors: Igor GONDA, James BLANCHARD, David C. CIPOLLA, Luiz Eduardo Moreira BERMUDEZ
  • Patent number: 9857387
    Abstract: The invention provides a method of detecting abnormal entry of gastrointestinal contents into the respiratory tract of a patient. The method comprises orally administering to a subject formulation comprising a detectable label that is not absorbed from the gastrointestinal tract but can be absorbed from the respiratory tract. The extent of the gastrointestinal contents entering the respiratory tract can be estimated by measuring the level of the detectable label in a body fluid, e.g., blood or urine.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: January 2, 2018
    Assignees: Aradigm Corporation, The Regents of The University of California
    Inventors: Igor Gonda, Homer A. Boushey
  • Patent number: 9844548
    Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: December 19, 2017
    Assignee: ARADIGM CORPORATION
    Inventors: Igor Gonda, James Blanchard, David C. Cipolla
  • Publication number: 20170184620
    Abstract: A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The qualitative analysis can be also expanded into quantitative analysis, enabling the estimation of either the concentration, or the amount, or both, of the gastrointestinal contents that entered the respiratory tract. The invention also provides methods of treatment based on the identification of aspiration using the methods of the invention.
    Type: Application
    Filed: March 13, 2017
    Publication date: June 29, 2017
    Inventors: Igor Gonda, Homer A. Boushey
  • Publication number: 20170071934
    Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: November 28, 2016
    Publication date: March 16, 2017
    Applicants: ARADIGM CORPORATION, OREGON STATE UNIVERSITY
    Inventors: Igor GONDA, James BLANCHARD, David C. CIPOLLA, Luiz Eduardoo Moreira BERMUDEZ
  • Patent number: 9592220
    Abstract: A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The qualitative analysis can be also expanded into quantitative analysis, enabling the estimation of either the concentration, or the amount, or both, of the gastrointestinal contents that entered the respiratory tract. The invention also provides methods of treatment based on the identification of aspiration using the methods of the invention.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: March 14, 2017
    Assignee: Aradigm Corporation
    Inventor: Igor Gonda
  • Patent number: 9532986
    Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: January 3, 2017
    Assignees: ARADIGM CORPORATION, OREGON STATE UNIVERSITY
    Inventors: Igor Gonda, James Blanchard, David C. Cipolla, Luiz Eduardo Moreira Bermudez
  • Publication number: 20160331744
    Abstract: An aerosolizable formulation comprised of a drug, a carrier and pH affecting component is disclosed. The drug is dissolved in the formulation at a concentration above which it remains in solution at neutral pH. This increases the concentration of the drug in solution making it possible to administer larger amounts of drug with the same or a smaller volume of formulation. When the formulation is aerosolized to small particles and inhaled into human lungs in small volumes (e.g. 0.05 to 0.5 mL) the fluids in the lungs neutralize the formulation causing the drug to participate out of solution. This results in the drug being delivered at a controlled rate below the rate at which drug is administered from a formulation initially at a neutral pH.
    Type: Application
    Filed: July 25, 2016
    Publication date: November 17, 2016
    Applicant: ARADIGM CORPORATION
    Inventors: David C. CIPOLLA, Igor GONDA
  • Patent number: 9457006
    Abstract: A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The qualitative analysis can be also expanded into quantitative analysis, enabling the estimation of either the concentration, or the amount, or both, of the gastrointestinal contents that entered the respiratory tract. The invention also provides methods of treatment based on the identification of aspiration using the methods of the invention.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: October 4, 2016
    Assignees: Aradigm Corporation, The Regents of the University of California
    Inventors: Igor Gonda, Homer A. Boushey
  • Publication number: 20160250227
    Abstract: The invention is directed to a transdermal drug delivery composition which includes at least one physiologically active agent; and at least one volatile solvent; and at least one viscosity modulating agent. The invention extends to methods of administering such a composition to a subject and treatment of subjects using the composition.
    Type: Application
    Filed: October 6, 2015
    Publication date: September 1, 2016
    Applicant: Acrux DDS Pty Ltd
    Inventors: Tony DIPIETRO, Andrew HUMBERSTONE, Igor GONDA, Adam WATKINSON, Kerrie SETIAWAN, Nina WILKINS
  • Patent number: 9421185
    Abstract: A method of diagnosing in a subject for the purpose of determining if the subject's gastrointestinal contents has entered the subject's respiratory tract. The qualitative analysis can be also expanded into quantitative analysis, enabling the estimation of either the concentration, or the amount, or both, of the gastrointestinal contents that entered the respiratory tract. The invention also provides methods of treatment based on the identification of aspiration using the methods of the invention.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: August 23, 2016
    Assignees: ARADIGM CORPORATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Igor Gonda, Homer A. Boushey
  • Patent number: 9372198
    Abstract: The invention provides a method of diagnosing entry of gastrointestinal contents into the respiratory tract of a patient suffering from reflux disease. The method comprises orally administering to a subject formulation comprising a detectable label that is not absorbed from the gastrointestinal tract but can be absorbed from the respiratory tract. The extent of the gastrointestinal contents entering the respiratory tract can be estimated by measuring the level of the detectable label in a body fluid, e.g., blood or urine.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: June 21, 2016
    Assignees: ARADIGM CORPORATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventor: Igor Gonda
  • Publication number: 20160120806
    Abstract: A formulation is disclosed which is comprised of a first solvent having a first active ingredient dissolved therein a plurality of microenvironments dispersed in the first solvent, the microenvironment being comprised of a shell having a dimension in a range of 50 nanometers to 100, the shell comprising an internal volume comprising a second solvent having a second active ingredient dissolved therein and nanocrystals of the second active ingredient.
    Type: Application
    Filed: January 12, 2016
    Publication date: May 5, 2016
    Applicant: ARADIGM CORPORATION
    Inventors: David C. CIPOLLA, Igor GONDA
  • Patent number: 9180194
    Abstract: The invention is directed to a transdermal drug delivery composition which includes at least one physiologically active agent; and at least one volatile solvent; and at least one viscosity modulating agent. The invention extends to methods of administering such a composition to a subject and treatment of subjects using the composition.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: November 10, 2015
    Assignee: ACRUX DDS PTY LTD
    Inventors: Tony Dipietro, Andrew Humberstone, Igor Gonda, Adam Watkinson, Kerrie Setiawan, Nina Wilkins
  • Publication number: 20150283133
    Abstract: Methods of treatment of NTM lung infections using formulations of liposomal ciprofloxacin. Specific liposome formulations and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: March 31, 2015
    Publication date: October 8, 2015
    Applicants: ARADIGM CORPORATION, OREGON STATE UNIVERSITY
    Inventors: Igor GONDA, James BLANCHARD, David C. CIPOLLA, LUIZ EDUARDO MOREIRA BERMUDEZ
  • Publication number: 20150283076
    Abstract: Methods for formulating a liposome comprised of a surfactant and a cryopreservative that can be frozen for long term stability, and upon thawing provides an immediate and sustained release delivery profile. Specific liposome formulations include anti-infectives and delivery of such for treatment of respiratory tract infections and other medical conditions, and devices and formulations used in connection with such are described.
    Type: Application
    Filed: February 11, 2015
    Publication date: October 8, 2015
    Applicant: ARADIGM CORPORATION
    Inventors: David C. CIPOLLA, Igor GONDA