Patents by Inventor Igor Mierau

Igor Mierau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chloride-Inducible Prokaryotic Expression System
    Publication number: 20220127629
    Abstract: The invention is directed to recombinant bacteria, a recombinant plasmid, a pharmaceutical composition and a kit as well as the use of a reconstitution medium comprising chloride ions to reconstitute the recombinant bacteria.
    Type: Application
    Filed: March 4, 2019
    Publication date: April 28, 2022
    Inventors: Thomas Wirth, Juha Yrjänheikki, Haritha Samaranayake, Hanna-Riikka Kärkkäinen, Jere Kurkipuro, Igor Mierau, Wesley Smith
  • Recombinant probiotic bacteria
    Patent number: 10738315
    Abstract: The invention is directed to recombinant probiotic bacteria, especially for use in the treatment of an inflammatory skin dysfunction, as well as a method for treating an inflammatory skin dysfunction.
    Type: Grant
    Filed: November 2, 2015
    Date of Patent: August 11, 2020
    Assignee: Aurealis Oy
    Inventors: Thomas Wirth, Juha Yrjänheikki, Haritha Samaranayake, Dirk Weber, Igor Mierau, Peter Allard Bron, Herwig Bachmann
  • Recombinant Probiotic Bacteria
    Publication number: 20180135062
    Abstract: The invention is directed to recombinant probiotic bacteria, especially for use in the treatment of an inflammatory skin dysfunction, as well as a method for treating an inflammatory skin dysfunction.
    Type: Application
    Filed: November 2, 2015
    Publication date: May 17, 2018
    Inventors: Thomas Wirth, Juha Yrjänheikki, Haritha Samaranayake, Dirk Weber, Igor Mierau, Peter Allard Bron, Herwig Bachmann
  • Production of Bioavailable Folic Acid
    Publication number: 20080248553
    Abstract: The invention provides a process of producing bio-available folate, i.e., folic acid having an increased proportion of monoglutamyl folate and a decreased proportion of polyglutamyl folate, by culturing food-grade microorganisms containing an active heterologous or homologous polyglutamyl hydrolase activity or containing increased activities of folate biosynthesis enzymes. The genes encoding the polyglutamyl hydrolase and the folate biosynthesis enzymes may be of various origin, e.g. from rodents or other mammals including man. Also provided is a foodstuff, especially a dairy product containing such monoglutamyl folate-producing microorganisms.
    Type: Application
    Filed: February 19, 2008
    Publication date: October 9, 2008
    Applicant: CAMPINA B.V.
    Inventors: Wilbert Feike Henricus Sybesma, Jeroen Hugenholtz, Igor Mierau, Maria Johanna Catharina Starrenburg, Michiel Kleerebezem, Willem Meindert De Vos
  • Production of bioavailable folic acid
    Publication number: 20040214261
    Abstract: The invention provides a process of producing bio-available folate, i.e. folic acid having an increased portion of monoglutamyl folate and a decreased proportion of polyglutamyl folate, by culturing food-grade micro-organisms containing an active heterologous or homologous polyglutamyl hydrolase activity or containing increased activities of folate biosynthesis enzymes. The genes encoding the polyglutamyl hydrolase and the folate biosynthesis enzymes may be of various origin, e.g. from rodents or other mammals including man. Also provided is a foodstuff, especially a dairy product containing such monoglutamyl folate-producing micro-organisms.
    Type: Application
    Filed: June 7, 2004
    Publication date: October 28, 2004
    Inventors: Wilbert Feike Henricus Sybesma, Igor Mierau, Maria Johanna Catharina Starrenburg, Michiel Kleerebezem, Willem Meindert De Vos