Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object comprises: generating an initial X-ray projection image with an imaging beam and an X-ray detector; based on a first position in a detector array of the X-ray detector, selecting a first kernel for convolution of a first portion of the initial projection image, wherein the first position corresponds to the first portion of the initial projection image; based on a second position in the detector array of the X-ray detector, selecting a second kernel for convolution of a second portion of the initial projection image, wherein the second position corresponds to the second portion of the initial projection image; convolving the first portion with the first kernel and the second portion with the second kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method of segmenting a reconstructed volume of a region of patient anatomy includes: determining an anatomical region associated with the reconstructed volume; detecting one or more metal objects disposed in an initial 3D metal object mask associated with the reconstructed volume; for each of the one or more metal objects disposed in the initial 3D metal object mask, determining a volume associated with the metal object; determining a value for at least one segmentation parameter based on the anatomical region and on the volume associated with the one or more metal objects; and generating a final 3D metal object mask associated with the reconstructed digital volume using the value for the segmentation parameter.

Abstract: A computer-implemented method for modifying X-ray projection images of a subject region includes: generating a set of combined two-dimensional (2D) projections of a subject region, wherein each combined 2D projection includes one or more mask-bordering pixels and one or more mask-edge pixels; forming a three-dimensional (3D) matrix of the set of combined 2D projections; based on the 3D matrix, generating a linear algebraic system for determining pixel values for pixels indicated in a set of 2D projection metal masks, wherein a first change in slope of pixel value associated with a mask-edge pixel of a combined 2D projection is constrained to equal a second change in slope of pixel value associated with a mask-bordering pixel of a combined 2D projection; determining values for a variable vector of the linear algebraic system; and generating a set of inpainted 2D projections by modifying initial 2D projections with values for the variable vector.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object comprises: generating an initial X-ray projection image with an imaging beam and an X-ray detector; based on a first position in a detector array of the X-ray detector, selecting a first kernel for convolution of a first portion of the initial projection image, wherein the first position corresponds to the first portion of the initial projection image; based on a second position in the detector array of the X-ray detector, selecting a second kernel for convolution of a second portion of the initial projection image, wherein the second position corresponds to the second portion of the initial projection image; convolving the first portion with the first kernel and the second portion with the second kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object, the method comprising: generating an initial X-ray projection image of an object with an imaging beam produced by an imaging system; based on a first transmission indicator for the object and on a second transmission indicator for at least one element of the imaging system, selecting a kernel for convolution of the initial projection image; convolving the initial X-ray projection image with the kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object comprises: generating an initial X-ray projection image with an imaging beam and an X-ray detector; based on a first position in a detector array of the X-ray detector, selecting a first kernel for convolution of a first portion of the initial projection image, wherein the first position corresponds to the first portion of the initial projection image; based on a second position in the detector array of the X-ray detector, selecting a second kernel for convolution of a second portion of the initial projection image, wherein the second position corresponds to the second portion of the initial projection image; convolving the first portion with the first kernel and the second portion with the second kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A computer-implemented method of reducing scatter in an X-ray projection image of an object, the method comprising: generating an initial X-ray projection image of an object with an imaging beam produced by an imaging system; based on a first transmission indicator for the object and on a second transmission indicator for at least one element of the imaging system, selecting a kernel for convolution of the initial projection image; convolving the initial X-ray projection image with the kernel to generate a scatter component of the initial X-ray projection image; and generating a corrected X-ray projection image by removing the scatter component from the initial X-ray projection image.

Abstract: A reconstructed volume of a region of patient anatomy is processed to reduce motion artifacts in the reconstructed volume. Autosegmentation of high-contrast structures present in an initial reconstructed volume is performed to generate a 3D representation of the high-contrast structures. 2D mask projections are generated by performing forward projection on the 3D representation, where each 2D mask projection includes location information indicating pixels that correspond to the high-contrast structures during the forward projection process. The acquired 2D projections are modified via in-painting to generate corrected 2D projections, where the acquired 2D projections are modified using information from the 2D mask projections. For example, pixels in the acquired 2D projections that are associated with high-contrast moving structures are replaced with low-contrast pixels.

Abstract: A reconstructed volume of a region of patient anatomy is processed to reduce motion artifacts in the reconstructed volume. Autosegmentation of high-contrast structures present in an initial reconstructed volume is performed to generate a 3D representation of the high-contrast structures. 2D mask projections are generated by performing forward projection on the 3D representation, where each 2D mask projection includes location information indicating pixels that correspond to the high-contrast structures during the forward projection process. The acquired 2D projections are modified via in-painting to generate corrected 2D projections, where the acquired 2D projections are modified using information from the 2D mask projections. For example, pixels in the acquired 2D projections that are associated with high-contrast moving structures are replaced with low-contrast pixels.

Abstract: A computer-implemented method of segmenting a reconstructed volume of a region of patient anatomy includes: determining an anatomical region associated with the reconstructed volume; detecting one or more metal objects disposed in an initial 3D metal object mask associated with the reconstructed volume; for each of the one or more metal objects disposed in the initial 3D metal object mask, determining a volume associated with the metal object; determining a value for at least one segmentation parameter based on the anatomical region and on the volume associated with the one or more metal objects; and generating a final 3D metal object mask associated with the reconstructed digital volume using the value for the segmentation parameter.

Abstract: A computer-implemented method for modifying X-ray projection images of a subject region includes: generating a set of combined two-dimensional (2D) projections of a subject region, wherein each combined 2D projection includes one or more mask-bordering pixels and one or more mask-edge pixels; forming a three-dimensional (3D) matrix of the set of combined 2D projections; based on the 3D matrix, generating a linear algebraic system for determining pixel values for pixels indicated in a set of 2D projection metal masks, wherein a first change in slope of pixel value associated with a mask-edge pixel of a combined 2D projection is constrained to equal a second change in slope of pixel value associated with a mask-bordering pixel of a combined 2D projection; determining values for a variable vector of the linear algebraic system; and generating a set of inpainted 2D projections by modifying initial 2D projections with values for the variable vector.

Abstract: A method of imaging a region of patient anatomy having a target volume includes performing an autosegmentation of a high-contrast portion of a first reconstructed volume of the region to generate a three-dimensional (3D) representation of the high-contrast portion disposed within the region and generating a set of two-dimensional (2D) mask projections of the region by performing a forward projection process on the 3D representation, wherein each 2D mask projection in the set of 2D mask projections includes location information indicating pixels that are blocked by the high-contrast portion during the forward projection process performed on the 3D representation.