Patents by Inventor Igor Rochman

Igor Rochman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glycosidation of 4,5-epoxymorphinan-6-ols
    Patent number: 6555665
    Abstract: Glycosidation of 4,5-Epoxymorphinan-6-ols with a Thioglycoside as a glycoside donor is disclosed. The process comprises reacting a 4,5-Epoxymorphinan-6-ol and a Thioglycoside in the presence of a thiophilic promoter under conditions capable of forming 4,5-Epoxymorphinan-6-glycosides. This novel approach was used for preparation of pharmaceutically important 4,5-Epoxymorphinan-6-&bgr;-D-glucuronides. The process provides both high stereo-selectivity and high yields.
    Type: Grant
    Filed: September 15, 2000
    Date of Patent: April 29, 2003
    Assignee: Cenes Limited
    Inventors: Arie Gutman, Genadi Nisnevitch, Lev Yudovitch, Igor Rochman