Patents by Inventor Igor V. Kurochkin

Igor V. Kurochkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human ALEX1 proteins
    Patent number: 8067540
    Abstract: The present invention provides a novel protein containing an armadillo repeat, a gene encoding this protein, and production and use thereof. The present inventors identified a gene named ALEX1 encoding a human-derived novel armadillo repeat-containing protein. It was clarified that ALEX1 interacts with several proteins including insulin-degrading enzyme, presenilin-1, and JNK interacting protein 1. This gene shows significantly decreased expression in cancer cells. The protein ALEX1 and the gene encoding this protein are usable as tools in testing for diseases such as cancer and Alzheimer's disease and developing pharmaceutical agents.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: November 29, 2011
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Igor V. Kurochkin, Natsumi Yonemitsu
  • NUCLEIC ACIDS ENCODING THE HUMAN ALEX1 PROTEIN
    Publication number: 20100210818
    Abstract: The present invention provides a novel protein containing an armadillo repeat, a gene encoding this protein, and production and use thereof. The present inventors identified a gene named ALEX1 encoding a human-derived novel armadillo repeat-containing protein. It was clarified that ALEX1 interacts with several proteins including insulin-degrading enzyme, presenilin-1, and JNK interacting protein 1. This gene shows significantly decreased expression in cancer cells. The protein ALEX1 and the gene encoding this protein are usable as tools in testing for diseases such as cancer and Alzheimer's disease and developing pharmaceutical agents.
    Type: Application
    Filed: February 16, 2010
    Publication date: August 19, 2010
    Applicant: CHUGAI SEIYAKU KABUSHIKI KAISHA
    Inventors: IGOR V. KUROCHKIN, NATSUMI YONEMITSU
  • Nucleic acids encoding the human ALEX1 protein
    Patent number: 7691992
    Abstract: The present invention provides a novel protein containing an armadillo repeat, a gene encoding this protein, and production and use thereof. The present inventors identified a gene named ALEX1 encoding a human-derived novel armadillo repeat-containing protein. It was clarified that ALEX1 interacts with several proteins including insulin-degrading enzyme, presenilin-1, and JNK interacting protein 1. This gene shows significantly decreased expression in cancer cells. The protein ALEX1 and the gene encoding this protein are usable as tools in testing for diseases such as cancer and Alzheimer's disease and developing pharmaceutical agents.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: April 6, 2010
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Igor V. Kurochkin, Natsumi Yonemitsu
  • Novel armadillo repeat-containing protein alex1
    Publication number: 20040038212
    Abstract: The present invention provides a novel protein containing an armadillo repeat, a gene encoding this protein, and production and use thereof. The present inventors identified a gene named ALEX1 encoding a human-derived novel armadillo repeat-containing protein. It was clarified that ALEX1 interacts with several proteins including insulin-degrading enzyme, presenilin-1, and JNK interacting protein 1. This gene shows significantly decreased expression in cancer cells. The protein ALEX1 and the gene encoding this protein are usable as tools in testing for diseases such as cancer and Alzheimer's disease and developing pharmaceutical agents.
    Type: Application
    Filed: January 15, 2003
    Publication date: February 26, 2004
    Inventors: Igor V Kurochkin, Natsumi Yonemitsu