Patents by Inventor Igor Vyacheslavovich Dudich

Igor Vyacheslavovich Dudich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Improved delivery of poorly water soluble drugs with aphafetoprotein stabilized with metal ions
    Publication number: 20160367515
    Abstract: The invention discloses a novel significantly improved carrier protein for pharmaceutical applications: metal ion-stabilized alfa-fetoprotein, AFP. The stabilized AFP serves as a novel universal drug delivery vehicle in formulating drugs to be targeted to cancer cells. Various transition metal ions form non-covalent adducts with AFP and stabilize it against physical and chemical factors in physiological fluids while not affecting its ability to target to AFP receptor-expressing cells.
    Type: Application
    Filed: November 18, 2014
    Publication date: December 22, 2016
    Applicant: Oy Safemed Ltd.
    Inventors: Elena Dudich, Igor Vyacheslavovich Dudich, Lidia Nikolaevna Semenkova, Eduard Tatulov, Timo Korpela
  • Recombinant alpha-fetoprotein and method of preparing
    Patent number: 7910327
    Abstract: The invention relates to the microbiological and medical industry, genetic engineering, biotechnology. A Saccharomyces cerevisiae yeast strain was obtained on the basis of constructing a recombinant plasmid DNA comprising a structural gene of a human alpha-fetoprotein (AFP) under the control of a regulatory promoter, providing the synthesis and production of AFP in a secreted soluble form, this AFP having activity identical or similar to the activity of a human AFP. The obtained recombinant AFP may be used as an active substance for the preparation of therapeutic agents for use in oncology, immunotherapy, cosmetology and also for the diagnosis of cancer and embryonic pathologies.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: March 22, 2011
    Inventors: Sergei Vladimirovich Benevolensky, Alexei Nikolaevich Marchenko, Dmitry Georgievich Kozlov, Sergei Sergeevich Zatsepin, Lyudmila Nikolaevna Shingarova, Igor Vyacheslavovich Dudich, Lidiya Nikolaevna Semenkova, Dmitry Igorevich Dudich, Eduard Borisovich Tatulov, Elena Ivanovna Dudich
  • Recombinant Alpha-Fetoprotein, Method and Means for Preparation Thereof, Compositions on the Base Thereof and Use Thereof
    Publication number: 20090233849
    Abstract: The invention relates to the microbiological and medical industry, genetic engineering, biotechnology. A Saccharomyces cerevisiae yeast strain was obtained on the basis of constructing a recombinant plasmid DNA comprising a structural gene of a human alpha-fetoprotein (AFP) under the control of a regulatory promoter, providing the synthesis and production of AFP in a secreted soluble form, this AFP having activity identical or similar to the activity of a human AFP. The obtained recombinant AFP may be used as an active substance for the preparation of therapeutic agents for use in oncology, immunotherapy, cosmetology and also for the diagnosis of cancer and embryonic pathologies.
    Type: Application
    Filed: July 7, 2005
    Publication date: September 17, 2009
    Inventors: Sergei Vladimirovich Benevolensky, Alexei Nikolaevich Marchenko, Dmitry Georgievich Kozlov, Sergei Sergeevich Zatsepin, Lyudmila Nikolaevna Shingarova, Igor Vyacheslavovich Dudich, Lidiya Nikolaevna Semenkova, Dmitry Igorevich Dudich, Eduard Borisovich Tatulov, Elena Ivanovna Dudich